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Helicobacter pylori Activates and Expands Lgr5+ Stem Cells Through Direct Colonization of the Gastric Glands

Gastroenterology (New York, N.Y. 1943), 2015-06, Vol.148 (7), p.1392-1404.e21

2015

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Single-cell dissection of transcriptional heterogeneity in human colon tumors

Nature biotechnology, 2011-12, Vol.29 (12), p.1120-1127

2011

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Geometry of the Gene Expression Space of Individual Cells

PLoS computational biology, 2015-07, Vol.11 (7), p.e1004224-e1004224

2015

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R-spondin-3 induces secretory, antimicrobial Lgr5 + cells in the stomach

Nature cell biology, 2019-07, Vol.21 (7), p.812

2019

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Control of inflammation by stromal Hedgehog pathway activation restrains colitis

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (47), p.E7545-E7553

2016

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IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans

Microbiome, 2023-03, Vol.11 (1), p.47-47, Article 47

2023

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A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis

Nature cell biology, 2014-12, Vol.16 (12), p.1238

2014

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Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (50), p.20667-20672

2012

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KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers

Gastroenterology (New York, N.Y. 1943), 2015-09, Vol.149 (3), p.705-717.e2

2015

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A phase I, randomized, ascending‐dose study to assess safety, pharmacokinetics, and activity of GDC‐8264, a RIP1 inhibitor, in healthy volunteers

Clinical and translational science, 2023-10, Vol.16 (10), p.1997-2009

2023

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Quantitative assessment of single-cell RNA-sequencing methods

Nature methods, 2014, Vol.11 (1), p.41

2014

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A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS

Annals of clinical and translational neurology, 2022-01, Vol.9 (1), p.50-66

2022

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Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL‐22Fc): A Potential Therapy for Epithelial Injury

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.177-189

2019

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A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti- Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers

Antimicrobial agents and chemotherapy, 2019-06, Vol.63 (6)

2019

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Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.1195-1205.e6

2012

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Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis

Gut, 2023-08, Vol.72 (8), p.1451

2023

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Lanthanum-Induced Gastrointestinal Histiocytosis

ACG case reports journal, 2015-04, Vol.2 (3), p.187-189

2015

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Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects

Science translational medicine, 2023-12, Vol.15 (727), p.eadf8366

2023

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Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)

Journal of pharmacokinetics and pharmacodynamics, 2024-04, Vol.51 (2), p.141-153

2024

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Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers

Clinical drug investigation, 2019-09, Vol.39 (9), p.873-887

2019

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5-ASA Induced Recurrent Myopericarditis and Cardiac Tamponade in a Patient with Ulcerative Colitis

Digestive diseases and sciences, 2013-08, Vol.58 (8), p.2148-2150

2013

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Rates of Major Cardiovascular Events in Severe Asthma: US Real-World and Clinical Trial-Eligible Populations

Annals of the American Thoracic Society, 2021-09, Vol.18 (9), p.1580-1584

2021

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The Myc Connection: ES Cells and Cancer

Cell, 2010-10, Vol.143 (2), p.184-186

2010

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Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers

Clinical drug investigation, 2019-09, Vol.39 (9), p.889-890

2019

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398 Loss of Gpsm2 Disrupts Stem Cell Dynamics and Mitotic Spindle Orientation in Normal Colon and Colon Cancer

Gastroenterology (New York, N.Y. 1943), 2014-05, Vol.146 (5), p.S-85-S-86

2014

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Helicobacter pylori Activates and Expands Lgr5+ Stem Cells Through Direct Colonization of the Gastric Glands

Single-cell dissection of transcriptional heterogeneity in human colon tumors

Geometry of the Gene Expression Space of Individual Cells

R-spondin-3 induces secretory, antimicrobial Lgr5 + cells in the stomach

Control of inflammation by stromal Hedgehog pathway activation restrains colitis

IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans

A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis

Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution

KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers

A phase I, randomized, ascending‐dose study to assess safety, pharmacokinetics, and activity of GDC‐8264, a RIP1 inhibitor, in healthy volunteers

Quantitative assessment of single-cell RNA-sequencing methods

A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS

Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL‐22Fc): A Potential Therapy for Epithelial Injury

A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti- Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers

Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis

Lanthanum-Induced Gastrointestinal Histiocytosis

Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects

Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)

Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers

5-ASA Induced Recurrent Myopericarditis and Cardiac Tamponade in a Patient with Ulcerative Colitis

Rates of Major Cardiovascular Events in Severe Asthma: US Real-World and Clinical Trial-Eligible Populations

The Myc Connection: ES Cells and Cancer

Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers

398 Loss of Gpsm2 Disrupts Stem Cell Dynamics and Mitotic Spindle Orientation in Normal Colon and Colon Cancer

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