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Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (32), p.E7486-E7494

2018

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Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1796-E1804

2017

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Visualization of the type III secretion sorting platform of Shigella flexneri

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (4), p.1047-1052

2015

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Comparative study of GBP recruitment on two cytosol-dwelling pathogens, Francisella novicida and Shigella flexneri highlights differences in GBP repertoire and in GBP1 motif requirements

Pathogens and disease, 2023-01, Vol.81

2023

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Disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate lyase enhances pathogen eradication by antibiotics

Journal of cystic fibrosis, 2021-03, Vol.20 (2), p.264-270

2021

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Direct real-time detection of the structural and biochemical events in the myosin power stroke

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.14272-14277

2015

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Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway

Cell reports (Cambridge), 2017-05, Vol.19 (7), p.1418-1430

2017

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Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (27), p.13582-13591

2019

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Shigella infection interferes with SUMOylation and increases PML-NB number

PloS one, 2015-04, Vol.10 (4), p.e0122585-e0122585

2015

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Hell's BELs: bacterial E3 ligases that exploit the eukaryotic ubiquitin machinery

PLoS pathogens, 2014-08, Vol.10 (8), p.e1004255-e1004255

2014

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Marine Bacteria, A Source for Alginolytic Enzyme to Disrupt Pseudomonas aeruginosa Biofilms

Marine drugs, 2019-05, Vol.17 (5), p.307

2019

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Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria

Cell host & microbe, 2018-05, Vol.23 (5), p.644-652.e5

2018

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Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals

PloS one, 2017-12, Vol.12 (12), p.e0189404-e0189404

2017

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Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

Molecular and Cellular Biology, 2014-02, Vol.34 (3), p.362-373

2014

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Type III secretion effectors of the IpaH family are E3 ubiquitin ligases

Cell host & microbe, 2007-03, Vol.1 (1), p.77-83

2007

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Microtubules provide force to promote membrane uncoating in vacuolar escape for a cyto-invasive bacterial pathogen

Nature communications, 2024-02, Vol.15 (1), p.1065-1065, Article 1065

2024

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A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure

Biophysical journal, 2017-07, Vol.113 (1), p.91-100

2017

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The bacterial pathogen–ubiquitin interface: lessons learned from Shigella

Cellular microbiology, 2015-01, Vol.17 (1), p.35-44

2015

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RACK1 promotes Shigella flexneri actin-mediated invasion, motility, and cell-to-cell spreading

iScience, 2023-11, Vol.26 (11), p.108216-108216, Article 108216

2023

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FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V

The Journal of biological chemistry, 2020-12, Vol.295 (51), p.17383-17397

2020

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Nutritional control via Tor signaling in Saccharomyces cerevisiae

Current opinion in microbiology, 2008-04, Vol.11 (2), p.153-160

2008

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A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system

PLoS pathogens, 2011-03, Vol.7 (3), p.e1001325-e1001325

2011

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Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease

Biomacromolecules, 2022-09, Vol.23 (9), p.3822-3830

2022

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Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

Nature structural & molecular biology, 2008-12, Vol.15 (12), p.1293-1301

2008

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E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

The EMBO journal, 2014-03, Vol.33 (5), p.437-449

2014

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Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin

Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke

Visualization of the type III secretion sorting platform of Shigella flexneri

Comparative study of GBP recruitment on two cytosol-dwelling pathogens, Francisella novicida and Shigella flexneri highlights differences in GBP repertoire and in GBP1 motif requirements

Disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate lyase enhances pathogen eradication by antibiotics

Direct real-time detection of the structural and biochemical events in the myosin power stroke

Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway

Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport

Shigella infection interferes with SUMOylation and increases PML-NB number

Hell's BELs: bacterial E3 ligases that exploit the eukaryotic ubiquitin machinery

Marine Bacteria, A Source for Alginolytic Enzyme to Disrupt Pseudomonas aeruginosa Biofilms

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria

Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

Type III secretion effectors of the IpaH family are E3 ubiquitin ligases

Microtubules provide force to promote membrane uncoating in vacuolar escape for a cyto-invasive bacterial pathogen

A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure

The bacterial pathogen–ubiquitin interface: lessons learned from Shigella

RACK1 promotes Shigella flexneri actin-mediated invasion, motility, and cell-to-cell spreading

FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V

Nutritional control via Tor signaling in Saccharomyces cerevisiae

A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system

Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

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