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Strategic, feasibility, economic, and cultural aspects of phase 0 approaches

Clinical and translational science, 2022-06, Vol.15 (6), p.1355-1379

2022

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Human ADME for YH12852 using wavelength scanning cavity ring-down spectroscopy (WS-CRDS) after a low radioactivity dose

Bioanalysis, 2020-01, Vol.12 (2), p.87-98

2020

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An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

Pharmacology research & perspectives, 2020-06, Vol.8 (3), p.e00599-n/a

2020

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Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?

Clinical and translational science, 2022-06, Vol.15 (6), p.1355-1379

2022

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Opportunities in low-level radiocarbon microtracing: applications and new technology

Future science OA, 2016-03, Vol.2 (1), p.FSO74-FSO74

2016

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A Dual‐Administration Microtracer Technique to Characterize the Absorption, Distribution, Metabolism, and Excretion of [14C]Seletalisib (UCB5857) in Healthy Subjects

Journal of clinical pharmacology, 2017-12, Vol.57 (12), p.1582-1590

2017

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Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

Clinical pharmacology: advances and applications, 2019-12, Vol.11, p.161-169

2019

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Absorption, Metabolism, and Excretion of 14 C-Emvododstat Following Repeat Daily Oral Dose Administration in Human Volunteers Using a Combination of Microtracer Radioactivity and High-Radioactivity Doses

Drug metabolism and disposition, 2024-01, Vol.52 (1), p.26-34

2024

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Dysfunctional muscarinic M2 autoreceptors in vagally induced bronchoconstriction of conscious guinea pigs after the early allergic reaction

European journal of pharmacology, 1996-12, Vol.318 (1), p.131-139

1996

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Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?: Is it time to change the drug development process in order to increase productivity?

Clinical and translational science, 2022-06, Vol.15 (6), p.1355

2022

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Early Radiation Effects on Muscarinic Receptor-Induced Secretory Responsiveness of the Parotid Gland in the Freely Moving Rat

Radiation research, 2000-03, Vol.153 (3), p.339-346

2000

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Effect of fenoterol-induced constitutive β2-adrenoceptor activity on contractile receptor function in airway smooth muscle

European journal of pharmacology, 2001-11, Vol.431 (3), p.353-359

2001

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Muscarinic M2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function

European journal of pharmacology, 1988-08, Vol.153 (1), p.73-82

1988

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Effects of fenoterol on β-adrenoceptor and muscarinic M2 receptor function in bovine tracheal smooth muscle

European journal of pharmacology, 2001-05, Vol.419 (2-3), p.253-259

2001

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Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea‐pig lung strip and inhibition of acetylcholine release in the guinea‐pig trachea with the selective muscarinic receptor antagonist tripitramine

British journal of pharmacology, 1997-09, Vol.122 (1), p.133-141

1997

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Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea‐pigs

British journal of pharmacology, 1995-02, Vol.114 (4), p.881-887

1995

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Muscarinic acetylcholine receptors and control of smooth muscle tone

Trends in pharmacological sciences (Regular ed.), 1994-11, Vol.15 (11), p.407-407

1994

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Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors

European journal of pharmacology, 1993-12, Vol.250 (2), p.267-279

1993

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Facilitatory beta 2-adrenoceptors on cholinergic and adrenergic nerve endings of the guinea pig trachea

American journal of physiology. Lung cellular and molecular physiology, 1999-03, Vol.276 (3), p.420-L425

1999

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β‐Agonist‐induced constitutive β 2 ‐adrenergic receptor activity in bovine tracheal smooth muscle

British journal of pharmacology, 2009-01, Vol.131 (5), p.915-920

2009

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Muscarinic inhibitory autoreceptors in different generations of human airways

American journal of respiratory and critical care medicine, 1996-07, Vol.154 (1), p.43-49

1996

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Effect of fenoterol-induced constitutive β 2-adrenoceptor activity on contractile receptor function in airway smooth muscle

European journal of pharmacology, 2001, Vol.431 (3), p.353-359

2001

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No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea

British journal of pharmacology, 1995-06, Vol.115 (4), p.665-671

1995

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Effects of fenoterol on β-adrenoceptor and muscarinic M 2 receptor function in bovine tracheal smooth muscle

European journal of pharmacology, 2001-05, Vol.419 (2), p.253-259

2001

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Contribution of a cholinergic reflex mechanism to allergen‐induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea‐pigs

British journal of pharmacology, 1995-01, Vol.114 (2), p.414-418

1995

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Strategic, feasibility, economic, and cultural aspects of phase 0 approaches

Human ADME for YH12852 using wavelength scanning cavity ring-down spectroscopy (WS-CRDS) after a low radioactivity dose

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?

Opportunities in low-level radiocarbon microtracing: applications and new technology

A Dual‐Administration Microtracer Technique to Characterize the Absorption, Distribution, Metabolism, and Excretion of [14C]Seletalisib (UCB5857) in Healthy Subjects

Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

Absorption, Metabolism, and Excretion of 14 C-Emvododstat Following Repeat Daily Oral Dose Administration in Human Volunteers Using a Combination of Microtracer Radioactivity and High-Radioactivity Doses

Dysfunctional muscarinic M2 autoreceptors in vagally induced bronchoconstriction of conscious guinea pigs after the early allergic reaction

Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?: Is it time to change the drug development process in order to increase productivity?

Early Radiation Effects on Muscarinic Receptor-Induced Secretory Responsiveness of the Parotid Gland in the Freely Moving Rat

Effect of fenoterol-induced constitutive β2-adrenoceptor activity on contractile receptor function in airway smooth muscle

Muscarinic M2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function

Effects of fenoterol on β-adrenoceptor and muscarinic M2 receptor function in bovine tracheal smooth muscle

Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea‐pig lung strip and inhibition of acetylcholine release in the guinea‐pig trachea with the selective muscarinic receptor antagonist tripitramine

Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea‐pigs

Muscarinic acetylcholine receptors and control of smooth muscle tone

Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors

Facilitatory beta 2-adrenoceptors on cholinergic and adrenergic nerve endings of the guinea pig trachea

β‐Agonist‐induced constitutive β 2 ‐adrenergic receptor activity in bovine tracheal smooth muscle

Muscarinic inhibitory autoreceptors in different generations of human airways

Effect of fenoterol-induced constitutive β 2-adrenoceptor activity on contractile receptor function in airway smooth muscle

No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea

Effects of fenoterol on β-adrenoceptor and muscarinic M 2 receptor function in bovine tracheal smooth muscle

Contribution of a cholinergic reflex mechanism to allergen‐induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea‐pigs

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