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The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Immunity (Cambridge, Mass.), 2013-01, Vol.38 (1), p.106-118

2013

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Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

PLoS biology, 2011-03, Vol.9 (3), p.e1000598-e1000598

2011

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The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

Nature communications, 2019-01, Vol.10 (1), p.498-498, Article 498

2019

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Embedding Assessment Literacy Can Enhance Graduate Attribute Development in a Biomedical Sciences Curriculum

British journal of biomedical science, 2024-05, Vol.81, p.12229-12229

2024

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Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade

Frontiers in microbiology, 2019-03, Vol.10, p.355-355

2019

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An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

PLoS biology, 2016-03, Vol.14 (3), p.e1002364

2016

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Discrete Clusters of Virus-Encoded MicroRNAs Are Associated with Complementary Strands of the Genome and the 7.2-Kilobase Stable Intron in Murine Cytomegalovirus

Journal of Virology, 2007-12, Vol.81 (24), p.13761-13770

2007

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Differential Proteomics Analysis of Synaptic Proteins Identifies Potential Cellular Targets and Protein Mediators of Synaptic Neuroprotection Conferred by the Slow Wallerian Degeneration (Wlds) Gene

Molecular & cellular proteomics, 2007-08, Vol.6 (8), p.1318-1330

2007

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Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State

Journal of Virology, 2011-10, Vol.85 (19), p.10286-10299

2011

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Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection

Frontiers in immunology, 2016-12, Vol.7, p.634-634

2016

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Chronic Mild Hypoxia Protects Heart-derived H9c2 Cells against Acute Hypoxia/Reoxygenation by Regulating Expression of the SUR2A Subunit of the ATP-sensitive K+ Channel

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.31444-31455

2003

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Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis

Steroids, 2015-07, Vol.99 (Pt B), p.219-229

2015

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Expression Profiling Reveals Novel Innate and Inflammatory Responses in the Jejunal Epithelial Compartment during Infection with Trichinella spiralis

Infection and Immunity, 2004-10, Vol.72 (10), p.6076-6086

2004

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A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

Biochimie, 2013-03, Vol.95 (3), p.613-621

2013

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GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

BMC genomics, 2005-12, Vol.6 (1), p.178-178, Article 178

2005

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A logic-based diagram of signalling pathways central to macrophage activation

BMC systems biology, 2008-04, Vol.2 (1), p.36-36, Article 36

2008

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Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy

The Journal of infectious diseases, 2021-02, Vol.223 (2), p.225-233

2021

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Extending signaling pathways with protein-interaction networks. Application to apoptosis

Omics (Larchmont, N.Y.), 2012-05, Vol.16 (5), p.245

2012

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Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint

American journal of obstetrics and gynecology, 2006-08, Vol.195 (2), p.406-414.e7

2006

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Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort

Neurology, 2010-04, Vol.74 (16), p.1260

2010

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Training Multidisciplinary Biomedical Informatics Students: Three Years of Experience

Journal of the American Medical Informatics Association : JAMIA, 2008-03, Vol.15 (2), p.246-254

2008

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Vaccination with inactivated murine gammaherpesvirus 68 strongly limits viral replication and latency and protects type I IFN receptor knockout mice from a lethal infection

Vaccine, 2004-03, Vol.22 (11), p.1433-1440

2004

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Regression of a Murine Gammaherpesvirus 68-Positive B-Cell Lymphoma Mediated by CD4 T Lymphocytes

Journal of Virology, 2001-04, Vol.75 (7), p.3480-3482

2001

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The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

Embedding Assessment Literacy Can Enhance Graduate Attribute Development in a Biomedical Sciences Curriculum

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

Discrete Clusters of Virus-Encoded MicroRNAs Are Associated with Complementary Strands of the Genome and the 7.2-Kilobase Stable Intron in Murine Cytomegalovirus

Differential Proteomics Analysis of Synaptic Proteins Identifies Potential Cellular Targets and Protein Mediators of Synaptic Neuroprotection Conferred by the Slow Wallerian Degeneration (Wlds) Gene

Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State

Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection

Chronic Mild Hypoxia Protects Heart-derived H9c2 Cells against Acute Hypoxia/Reoxygenation by Regulating Expression of the SUR2A Subunit of the ATP-sensitive K+ Channel

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis

Expression Profiling Reveals Novel Innate and Inflammatory Responses in the Jejunal Epithelial Compartment during Infection with Trichinella spiralis

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

A logic-based diagram of signalling pathways central to macrophage activation

Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy

Extending signaling pathways with protein-interaction networks. Application to apoptosis

Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint

Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort

Weight changes and adverse pregnancy outcomes with dolutegravir- and tenofovir alafenamide fumarate-containing antiretroviral treatment regimens during pregnancy and postpartum

Training Multidisciplinary Biomedical Informatics Students: Three Years of Experience

Vaccination with inactivated murine gammaherpesvirus 68 strongly limits viral replication and latency and protects type I IFN receptor knockout mice from a lethal infection

Regression of a Murine Gammaherpesvirus 68-Positive B-Cell Lymphoma Mediated by CD4 T Lymphocytes

An interferon regulated microRNA provides cell-intrinsec anti-viral immunity through multihit host-directed targeting of the sterol pathway

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