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TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Cell, 2020-08, Vol.182 (4), p.886-900.e17

2020

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Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

Immunity (Cambridge, Mass.), 2021-06, Vol.54 (6), p.1320-1337.e4

2021

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Therapy-Induced Senescence Drives Bone Loss

Cancer research (Chicago, Ill.), 2020-03, Vol.80 (5), p.1171-1182

2020

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Regulation of the Immune System Development by Glucocorticoids and Sex Hormones

Frontiers in immunology, 2021-06, Vol.12, p.672853-672853

2021

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Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

eLife, 2020-08, Vol.9

2020

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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

The Journal of experimental medicine, 2016-05, Vol.213 (5), p.827-840

2016

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Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

Scientific reports, 2017-07, Vol.7 (1), p.6630-11, Article 6630

2017

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42. Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing

Journal of bone oncology, 2024-04, Vol.45, p.100580, Article 100580

2024

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Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.950-960

2014

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39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis

Journal of bone oncology, 2024-04, Vol.45, p.100577, Article 100577

2024

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TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells

Frontiers in immunology, 2024-05, Vol.15, p.1368946

2024

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Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma

PloS one, 2021-07, Vol.16 (7), p.e0254426-e0254426

2021

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New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

Journal of medicinal chemistry, 2015-08, Vol.58 (15), p.5789-5807

2015

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How the Immune System Responds to Allergy Immunotherapy

Biomedicines, 2022-11, Vol.10 (11), p.2825

2022

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Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma

Oncoimmunology, 2013-12, Vol.2 (12), p.e26663-e26663

2013

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IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

Journal for immunotherapy of cancer, 2022-03, Vol.10 (3), p.e003858

2022

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Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset

Journal for immunotherapy of cancer, 2022-01, Vol.10 (1)

2022

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Abstract 3925: Cancer-associated fibroblast-derived Dickkopf-1 impairs anti-tumor immunity in breast cancer by suppressing NK cell-mediated cytotoxicity

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.3925-3925

2024

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Abstract 662: Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.662-662

2023

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Abstract LB100: Dickkopf-1 induces breast cancer progression by limiting T cell infiltration into the tumor microenvironment

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.LB100-LB100

2022

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Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption

The FASEB journal, 2021-09, Vol.35 (9), p.e21837-n/a

2021

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Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans -Presentation

Cancer immunology research, 2018-07, Vol.6 (7), p.860-869

2018

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Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Oncoimmunology, 2016-10, Vol.5 (10), p.e1218105-e1218105

2016

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Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56 bright CD16 - subset

Journal for immunotherapy of cancer, 2022-01, Vol.10 (1), p.e003385

2022

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Constitutive activation of NF-[kappa]B inducing kinase -Cre drives spontaneous soft tissue sarcoma

PloS one, 2021-07, Vol.16 (7), p.e0254426

2021

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TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

Therapy-Induced Senescence Drives Bone Loss

Regulation of the Immune System Development by Glucocorticoids and Sex Hormones

Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

42. Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1

39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis

TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells

Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

How the Immune System Responds to Allergy Immunotherapy

Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset

Abstract 3925: Cancer-associated fibroblast-derived Dickkopf-1 impairs anti-tumor immunity in breast cancer by suppressing NK cell-mediated cytotoxicity

Abstract 662: Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing

Abstract LB100: Dickkopf-1 induces breast cancer progression by limiting T cell infiltration into the tumor microenvironment

Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption

Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans -Presentation

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56 bright CD16 - subset

Constitutive activation of NF-[kappa]B inducing kinase -Cre drives spontaneous soft tissue sarcoma

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