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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

Nature communications, 2020-08, Vol.11 (1), p.4022-4022, Article 4022

2020

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Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria

Nature communications, 2021-03, Vol.12 (1), p.1422-1422, Article 1422

2021

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Automated structure prediction of trans-acyltransferase polyketide synthase products

Nature chemical biology, 2019-08, Vol.15 (8), p.813-821

2019

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Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908

Journal of antibiotics, 2020-03, Vol.73 (3), p.171-174

2020

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Pseudoalteropeptide A, a novel lipopeptide from the marine bacterium Pseudoalteromonas piscicida SWA4_PA4 isolated from marine seaweed

Journal of antibiotics, 2021-02, Vol.74 (2), p.105-110

2021

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Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

Nature chemical biology, 2015-09, Vol.11 (9), p.705-712

2015

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Effect of tolytoxin on tunneling nanotube formation and function

Scientific reports, 2019-04, Vol.9 (1), p.5741-5741, Article 5741

2019

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The Peptide A-3302-B Isolated from a Marine Bacterium Micromonospora sp. Inhibits HSV-2 Infection by Preventing the Viral Egress from Host Cells

International journal of molecular sciences, 2022-01, Vol.23 (2), p.947

2022

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Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source

Angewandte Chemie International Edition, 2018-10, Vol.57 (44), p.14519-14523

International ed. in English, 2018

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A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900

Bioscience, biotechnology, and biochemistry, 2021-03, Vol.85 (4), p.890-894

2021

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Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Chembiochem : a European journal of chemical biology, 2020-02, Vol.21 (4), p.564-571

2020

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N-Succinyltransferase Encoded by a Cryptic Siderophore Biosynthesis Gene Cluster in Streptomyces Modifies Structurally Distinct Antibiotics

mBio, 2022-10, Vol.13 (5), p.e0178922-e0178922

2022

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Yaku’amides A and B, Cytotoxic Linear Peptides Rich in Dehydroamino Acids from the Marine Sponge Ceratopsion sp

Journal of the American Chemical Society, 2010-12, Vol.132 (50), p.17692-17694

2010

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Curacin E from the Brittle Star Ophiocoma scolopendrina

Journal of natural products (Washington, D.C.), 2016-10, Vol.79 (10), p.2754-2757

2016

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Gracilioethers A−C, Antimalarial Metabolites from the Marine Sponge Agelas gracilis

Journal of organic chemistry, 2009-06, Vol.74 (11), p.4203-4207

2009

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Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin

Toxicon (Oxford), 2009-05, Vol.53 (6), p.680-684

2009

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Cytotoxic polyacetylenes related to petroformyne-1 from the marine sponge Petrosia sp

Tetrahedron, 2009-07, Vol.65 (27), p.5204-5208

2009

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Ophiodilactones A and B, Cytotoxic Tetrameric Phenylpropanoids, from the Ophiuroid Ophiocoma scolopendrina

Journal of organic chemistry, 2009-06, Vol.74 (11), p.4396-4399

2009

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Isolation of Salsolinol, a Tetrahydroisoquinoline Alkaloid, from the Marine Sponge Xestospongia cf. vansoesti as a Proteasome Inhibitor

Chemical and Pharmaceutical Bulletin, 2011/02/01, Vol.59(2), pp.287-290

2011

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Penasins A−E, Long-Chain Cytotoxic Sphingoid Bases, from a Marine Sponge Penares sp

Journal of natural products (Washington, D.C.), 2010-11, Vol.73 (11), p.1947-1950

2010

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Inconspicamide, new N-acylated serinol from the marine sponge Stelletta inconspicua

Bioscience, biotechnology, and biochemistry, 2008-11, Vol.72 (11), p.3055-3058

2008

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Atropopeptides are a Novel Family of Ribosomally Synthesized and Posttranslationally Modified Peptides with a Complex Molecular Shape

Angewandte Chemie International Edition, 2022-10, Vol.61 (41), p.e202208361-n/a

International ed. in English, 2022

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Cyanobacterial ent‐Sterol‐Like Natural Products from a Deviated Ubiquinone Pathway

Angewandte Chemie International Edition, 2017-04, Vol.56 (18), p.4987-4990

International ed. in English, 2017

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Exploration, expansion and definition of the atropopeptide family of ribosomally synthesized and posttranslationally modified peptides

Chemical science (Cambridge), 2024-09

2024

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Aranazoles: Extensively Chlorinated Nonribosomal Peptide–Polyketide Hybrids from the Cyanobacterium Fischerella sp. PCC 9339

Organic letters, 2018-09, Vol.20 (17), p.5238-5241

2018

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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria

Automated structure prediction of trans-acyltransferase polyketide synthase products

Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908

Pseudoalteropeptide A, a novel lipopeptide from the marine bacterium Pseudoalteromonas piscicida SWA4_PA4 isolated from marine seaweed

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

Effect of tolytoxin on tunneling nanotube formation and function

The Peptide A-3302-B Isolated from a Marine Bacterium Micromonospora sp. Inhibits HSV-2 Infection by Preventing the Viral Egress from Host Cells

Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source

A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

N-Succinyltransferase Encoded by a Cryptic Siderophore Biosynthesis Gene Cluster in Streptomyces Modifies Structurally Distinct Antibiotics

Yaku’amides A and B, Cytotoxic Linear Peptides Rich in Dehydroamino Acids from the Marine Sponge Ceratopsion sp

Curacin E from the Brittle Star Ophiocoma scolopendrina

Gracilioethers A−C, Antimalarial Metabolites from the Marine Sponge Agelas gracilis

Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin

Cytotoxic polyacetylenes related to petroformyne-1 from the marine sponge Petrosia sp

Ophiodilactones A and B, Cytotoxic Tetrameric Phenylpropanoids, from the Ophiuroid Ophiocoma scolopendrina

Isolation of Salsolinol, a Tetrahydroisoquinoline Alkaloid, from the Marine Sponge Xestospongia cf. vansoesti as a Proteasome Inhibitor

Penasins A−E, Long-Chain Cytotoxic Sphingoid Bases, from a Marine Sponge Penares sp

Inconspicamide, new N-acylated serinol from the marine sponge Stelletta inconspicua

Atropopeptides are a Novel Family of Ribosomally Synthesized and Posttranslationally Modified Peptides with a Complex Molecular Shape

Cyanobacterial ent‐Sterol‐Like Natural Products from a Deviated Ubiquinone Pathway

Exploration, expansion and definition of the atropopeptide family of ribosomally synthesized and posttranslationally modified peptides

Aranazoles: Extensively Chlorinated Nonribosomal Peptide–Polyketide Hybrids from the Cyanobacterium Fischerella sp. PCC 9339

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