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Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy

Scientific reports, 2020-05, Vol.10 (1), p.7456-7456, Article 7456

2020

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Nanoparticle-Assisted Targeted Delivery of Eye-Specific Genes to Eyes Significantly Improves the Vision of Blind Mice In Vivo

Nano letters, 2014-09, Vol.14 (9), p.5257-5263

2014

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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection

Cell death & disease, 2022-07, Vol.13 (7), p.613-613, Article 613

2022

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Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα

Diabetes (New York, N.Y.), 2017-06, Vol.66 (6), p.1671-1682

2017

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Loss of Neuroprotective Survival Signal in Mice Lacking Insulin Receptor Gene in Rod Photoreceptor Cells

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19781-19792

2008

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A non‐canonical rhodopsin‐mediated insulin receptor signaling pathway in retinal photoreceptor neurons

Cell biology international, 2020-04, Vol.44 (4), p.1020-1027

2020

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Aerobic Glycolysis in the Retina: Functional Roles of Pyruvate Kinase Isoforms

Frontiers in cell and developmental biology, 2020-04, Vol.8, p.266-266

Rajala, Raju V S

2020

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MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization

FEBS letters, 2015-04, Vol.589 (10), p.1143-1149

2015

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Unlocking the role of lactate: metabolic pathways, signaling, and gene regulation in postmitotic retinal cells

Frontiers in ophthalmology, 2023-11, Vol.3, p.1296624

2023

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Age-Related Changes in the Glycolytic Enzymes of M2-Isoform of Pyruvate Kinase and Fructose-1,6-Bisphosphate Aldolase: Implications to Age-Related Macular Degeneration

Aging and disease, 2024-04

2024

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Lipid Nanoparticles for Ocular Gene Delivery

Journal of Functional Biomaterials, 2015-06, Vol.6 (2), p.379-394

2015

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Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa Mice

Retinal Degenerative Diseases, 2018-01, p.491-497

2018

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Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Cell death & disease, 2018-02, Vol.9 (2), p.240-18, Article 240

2018

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Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14

Biomolecules (Basel, Switzerland), 2021-04, Vol.11 (4), p.602

2021

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Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

Biology (Basel, Switzerland), 2020-11, Vol.9 (11), p.384

2020

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Phosphoinositide Lipids in Ocular Tissues

Biology (Basel, Switzerland), 2020-06, Vol.9 (6), p.125

2020

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Enhanced Retinal Insulin Receptor-activated Neuroprotective Survival Signal in Mice Lacking the Protein-tyrosine Phosphatase-1B Gene

The Journal of biological chemistry, 2010-03, Vol.285 (12), p.8894-8904

2010

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Diabetes Reduces Autophosphorylation of Retinal Insulin Receptor and Increases Protein-Tyrosine Phosphatase-1B Activity

Investigative ophthalmology & visual science, 2009-03, Vol.50 (3), p.1033-1040

2009

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Phosphorylated Grb14 Is an Endogenous Inhibitor of Retinal Protein Tyrosine Phosphatase 1B, and Light-Dependent Activation of Src Phosphorylates Grb14

Molecular and Cellular Biology, 2011-10, Vol.31 (19), p.3975-3987

2011

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Impaired Association of Retinal Degeneration-3 with Guanylate Cyclase-1 and Guanylate Cyclase-activating Protein-1 Leads to Leber Congenital Amaurosis-1

The Journal of biological chemistry, 2015-02, Vol.290 (6), p.3488-3499

2015

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Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2022-08, Vol.1867 (8), p.159161-159161, Article 159161

2022

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Loss of human disease protein retinitis pigmentosa GTPase regulator (RPGR) differentially affects rod or cone-enriched retina

Human molecular genetics, 2016-04, Vol.25 (7), p.1345-1356

2016

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Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study

British journal of anaesthesia : BJA, 2018-07, Vol.121 (1), p.281-290

2018

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Insulin receptor regulates photoreceptor CNG channel activity

American journal of physiology: endocrinology and metabolism, 2012-12, Vol.303 (11), p.E1363-E1372

2012

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Phosphoinositide 3-kinase signaling in the vertebrate retina

Journal of lipid research, 2010-01, Vol.51 (1), p.4-22

Rajala, Raju V.S

2010

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Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy

Nanoparticle-Assisted Targeted Delivery of Eye-Specific Genes to Eyes Significantly Improves the Vision of Blind Mice In Vivo

Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection

Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα

Loss of Neuroprotective Survival Signal in Mice Lacking Insulin Receptor Gene in Rod Photoreceptor Cells

A non‐canonical rhodopsin‐mediated insulin receptor signaling pathway in retinal photoreceptor neurons

Aerobic Glycolysis in the Retina: Functional Roles of Pyruvate Kinase Isoforms

MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization

Unlocking the role of lactate: metabolic pathways, signaling, and gene regulation in postmitotic retinal cells

Age-Related Changes in the Glycolytic Enzymes of M2-Isoform of Pyruvate Kinase and Fructose-1,6-Bisphosphate Aldolase: Implications to Age-Related Macular Degeneration

Lipid Nanoparticles for Ocular Gene Delivery

Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa Mice

Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

Phosphoinositide Lipids in Ocular Tissues

Enhanced Retinal Insulin Receptor-activated Neuroprotective Survival Signal in Mice Lacking the Protein-tyrosine Phosphatase-1B Gene

Diabetes Reduces Autophosphorylation of Retinal Insulin Receptor and Increases Protein-Tyrosine Phosphatase-1B Activity

Phosphorylated Grb14 Is an Endogenous Inhibitor of Retinal Protein Tyrosine Phosphatase 1B, and Light-Dependent Activation of Src Phosphorylates Grb14

Impaired Association of Retinal Degeneration-3 with Guanylate Cyclase-1 and Guanylate Cyclase-activating Protein-1 Leads to Leber Congenital Amaurosis-1

Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures

Loss of human disease protein retinitis pigmentosa GTPase regulator (RPGR) differentially affects rod or cone-enriched retina

Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study

Insulin receptor regulates photoreceptor CNG channel activity

Phosphoinositide 3-kinase signaling in the vertebrate retina

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