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5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

Biochimica et biophysica acta, 2015-04, Vol.1851 (4), p.331-339

2015

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Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

Biochemical and biophysical research communications, 2010-05, Vol.396 (1), p.105-110

2010

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5-Lipoxygenase: mechanisms of regulation

Journal of lipid research, 2009-04, Vol.50, p.S40-S45

2009

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5-Lipoxygenase: regulation of expression and enzyme activity

Trends in biochemical sciences (Amsterdam. Regular ed.), 2007-07, Vol.32 (7), p.332-341

2007

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Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

Journal of allergy and clinical immunology, 2010-11, Vol.126 (5), p.1032-1040.e4

2010

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GM‐CSF– and M‐CSF–primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures

The FASEB journal, 2017-10, Vol.31 (10), p.4370-4381

2017

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Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Cell metabolism, 2008-09, Vol.8 (3), p.237-248

2008

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Time‐resolved in situ assembly of the leukotriene‐synthetic 5‐lipoxygenase/5‐lipoxygenase‐activating protein complex in blood leukocytes

The FASEB journal, 2016-01, Vol.30 (1), p.276-285

2016

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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4

Journal of lipid research, 2016-09, Vol.57 (9), p.1659-1669

2016

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Formation of eicosanoids and other oxylipins in human macrophages

Biochemical pharmacology, 2022-10, Vol.204, p.115210-115210, Article 115210

Radmark, Olof

2022

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ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (50), p.19881-19886

2008

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Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.11371-11376

2014

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Pulmonary sarcoidosis is associated with exosomal vitamin D–binding protein and inflammatory molecules

Journal of allergy and clinical immunology, 2017-04, Vol.139 (4), p.1186-1194

2017

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Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1

Cancer letters, 2019-03, Vol.444, p.1-8

2019

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Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

The Journal of clinical investigation, 2017-08, Vol.127 (8), p.3167-3176

2017

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Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (15), p.8573-8583

2020

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Modulation of microRNA processing by 5‐lipoxygenase

The FASEB journal, 2021-02, Vol.35 (2), p.e21193-n/a

2021

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Human 5-lipoxygenase regulates transcription by association to euchromatin

Biochemical pharmacology, 2022-09, Vol.203, p.115187-115187, Article 115187

2022

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In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis

Pharmacological research, 2014-09, Vol.87, p.1-7

2014

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Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes

The FASEB journal, 2011-10, Vol.25 (10), p.3377-3387

2011

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Lipoxin and resolvin biosynthesis is dependent on 5‐lipoxygenase activating protein

The FASEB journal, 2015-12, Vol.29 (12), p.5029-5043

2015

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mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity

Endocrine-related cancer, 2015-08, Vol.22 (4), p.665-678

2015

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12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15774-15779

2010

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Ribonuclease activity and RNA binding of recombinant human Dicer

The EMBO journal, 2002-11, Vol.21 (21), p.5864-5874

2002

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Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenesis

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (3), p.1238-1243

2003

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5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

5-Lipoxygenase: mechanisms of regulation

5-Lipoxygenase: regulation of expression and enzyme activity

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

GM‐CSF– and M‐CSF–primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Time‐resolved in situ assembly of the leukotriene‐synthetic 5‐lipoxygenase/5‐lipoxygenase‐activating protein complex in blood leukocytes

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4

Formation of eicosanoids and other oxylipins in human macrophages

ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Pulmonary sarcoidosis is associated with exosomal vitamin D–binding protein and inflammatory molecules

Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells

Modulation of microRNA processing by 5‐lipoxygenase

Human 5-lipoxygenase regulates transcription by association to euchromatin

In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes

Lipoxin and resolvin biosynthesis is dependent on 5‐lipoxygenase activating protein

mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity

12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Ribonuclease activity and RNA binding of recombinant human Dicer

Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenesis

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