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Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells

Scientific reports, 2019-07, Vol.9 (1), p.10462-13, Article 10462

2019

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GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity

Nature communications, 2019-10, Vol.10 (1), p.4804-13, Article 4804

2019

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Multi-functional adaptor SKAP1: regulator of integrin activation, the stop-signal, and the proliferation of T cells

Frontiers in immunology, 2023, Vol.14, p.1192838-1192838

2023

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Blocking Mitotic Exit of Ovarian Cancer Cells by Pharmaceutical Inhibition of the Anaphase-Promoting Complex Reduces Chromosomal Instability

Neoplasia (New York, N.Y.), 2019-04, Vol.21 (4), p.363-375

2019

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PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells

Nature communications, 2018-03, Vol.9 (1), p.1106-17, Article 1106

2018

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Sequential Targeting of PLK1 and PARP1 Reverses the Resistance to PARP Inhibitors and Enhances Platin-Based Chemotherapy in BRCA-Deficient High-Grade Serous Ovarian Cancer with KRAS Amplification

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10892

2022

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Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity

Molecular and Cellular Biology, 2010-12, Vol.30 (24), p.5726-5740

2010

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The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells

Cancers, 2021-07, Vol.13 (15), p.3658

2021

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The Prognostic Relevance of the Proliferation Markers Ki-67 and Plk1 in Early-Stage Ovarian Cancer Patients With Serous, Low-Grade Carcinoma Based on mRNA and Protein Expression

Frontiers in oncology, 2020-10, Vol.10, p.558932-558932

2020

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Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells

ACS chemical biology, 2015-11, Vol.10 (11), p.2570-2579

2015

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Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8

Cell research, 2016-08, Vol.26 (8), p.914-934

2016

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Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

BMC research notes, 2018-12, Vol.11 (1), p.869-869, Article 869

2018

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Synthetic lethality in CCNE1 -amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics

Oncotarget, 2018-05, Vol.9 (40), p.25842-25859

2018

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Synergistic Sensitization of High-Grade Serous Ovarian Cancer Cells Lacking Caspase-8 Expression to Chemotherapeutics Using Combinations of Small-Molecule BRD4 and CDK9 Inhibitors

Cancers, 2023-12, Vol.16 (1), p.107

2023

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Rescue of p53 functions by in vitro‐transcribed mRNA impedes the growth of high‐grade serous ovarian cancer

Cancer communications (London, England), 2024-01, Vol.44 (1), p.101-126

2024

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Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy

Cancers, 2022-11, Vol.14 (22), p.5500

2022

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The role of PLK1 in cancer exhibiting chromosomal instability

Molecular & cellular oncology, 2018-11, Vol.5 (6), p.e1485539-e1485539

2018

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Non-mitotic functions of polo-like kinases in cancer cells

Biochimica et biophysica acta. Reviews on cancer, 2021-01, Vol.1875 (1), p.188467, Article 188467

2021

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Targeting polo-like kinase 1: advancements and future directions in anti-cancer drug discovery

Expert opinion on drug discovery, 2024-07, p.1-5

2024

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Erratum: Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Nature (London), 2016-03, Vol.536 (7616), p.359-359

2016

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Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1

Oncogene, 2023-08, Vol.42 (34), p.2590-2590

2023

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A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1

Oncogene, 2022-01, Vol.41 (3), p.372-386

2022

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Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain‑4 (BRD4) by Tuning Kinase Selectivity

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2618-2637

2019

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The regulation of RNA Polymerase II mediated transcription by Caspase-8 in ovarian cancer

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e18082-e18082

2020

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CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Nature (London), 2015-01, Vol.517 (7534), p.386-390

2015

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Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells

GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity

Multi-functional adaptor SKAP1: regulator of integrin activation, the stop-signal, and the proliferation of T cells

Blocking Mitotic Exit of Ovarian Cancer Cells by Pharmaceutical Inhibition of the Anaphase-Promoting Complex Reduces Chromosomal Instability

PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells

Sequential Targeting of PLK1 and PARP1 Reverses the Resistance to PARP Inhibitors and Enhances Platin-Based Chemotherapy in BRCA-Deficient High-Grade Serous Ovarian Cancer with KRAS Amplification

Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity

The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells

The Prognostic Relevance of the Proliferation Markers Ki-67 and Plk1 in Early-Stage Ovarian Cancer Patients With Serous, Low-Grade Carcinoma Based on mRNA and Protein Expression

Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells

Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8

Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

Synthetic lethality in CCNE1 -amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics

Synergistic Sensitization of High-Grade Serous Ovarian Cancer Cells Lacking Caspase-8 Expression to Chemotherapeutics Using Combinations of Small-Molecule BRD4 and CDK9 Inhibitors

Rescue of p53 functions by in vitro‐transcribed mRNA impedes the growth of high‐grade serous ovarian cancer

Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy

The role of PLK1 in cancer exhibiting chromosomal instability

Non-mitotic functions of polo-like kinases in cancer cells

Targeting polo-like kinase 1: advancements and future directions in anti-cancer drug discovery

Erratum: Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1

A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1

Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain‑4 (BRD4) by Tuning Kinase Selectivity

The regulation of RNA Polymerase II mediated transcription by Caspase-8 in ovarian cancer

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

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