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Inhibitors of the Polo-Box Domain of Polo-Like Kinase 1

Chembiochem : a European journal of chemical biology, 2016-04, Vol.17 (8), p.650-656

2016

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The hydrophobically-tagged MDM2-p53 interaction inhibitor Nutlin-3a-HT is more potent against tumor cells than Nutlin-3a

Chemical communications (Cambridge, England), 2019-11, Vol.55 (95), p.14351-14354

2019

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Polymer Nanocomposite Ultrafiltration Membranes: The Influence of Polymeric Additive, Dispersion Quality and Particle Modification on the Integration of Zinc Oxide Nanoparticles into Polyvinylidene Difluoride Membranes

Membranes (Basel), 2020-08, Vol.10 (9), p.197

2020

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Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b

Scientific reports, 2017-04, Vol.7 (1), p.819-9, Article 819

2017

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iSPAAC: Isomer‐Free Generation of a Bcl‐xL‐Inhibitor in Living Cells

Chemistry : a European journal, 2018-09, Vol.24 (52), p.13762-13766

2018

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Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

Nature chemical biology, 2011-07, Vol.7 (9), p.595

2011

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Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells

Scientific reports, 2017-12, Vol.7 (1), p.17390-10, Article 17390

2017

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FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

Blood, 2012-08, Vol.120 (9), p.1843-1855

2012

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Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5

Chembiochem : a European journal of chemical biology, 2008-03, Vol.9 (5), p.723-727

2008

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Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells

ACS chemical biology, 2015-11, Vol.10 (11), p.2570-2579

2015

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A High-Throughput Fluorescence Polarization-Based Assay for the SH2 Domain of STAT4

Methods and protocols, 2022-11, Vol.5 (6), p.93

2022

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GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis

Frontiers in immunology, 2023-10, Vol.14, p.1165306-1165306

2023

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Polo-Box Domain Inhibitor Poloxin Activates the Spindle Assembly Checkpoint and Inhibits Tumor Growth in Vivo

The American journal of pathology, 2011-10, Vol.179 (4), p.2091-2099

2011

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A high-throughput assay based on fluorescence polarization for inhibitors of the polo-box domain of polo-like kinase 1

Analytical biochemistry, 2008-12, Vol.383 (2), p.205-209

2008

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MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

Acta pharmaceutica Sinica. B, 2019-09, Vol.9 (5), p.1021-1034

2019

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Inhibition of Protein–Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases

Angewandte Chemie (International ed.), 2017-09, Vol.56 (40), p.12048-12050

Berg, Thorsten

International ed. in English, 2017

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A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3

Analytical biochemistry, 2004-07, Vol.330 (1), p.114-118

2004

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Mit organischen Substanzen hemmen

Nachrichten aus der Chemie, 2016-10, Vol.64 (10), p.960-964

Berg, Thorsten

2016

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Die Hemmung von Protein‐Protein‐Wechselwirkungen: neue Ansätze zur Entwicklung von Wirkstoffen gegen Tropenkrankheiten

Angewandte Chemie, 2017-09, Vol.129 (40), p.12214-12216

Berg, Thorsten

2017

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Development of high-throughput assays based on fluorescence polarization for inhibitors of the polo-box domains of polo-like kinases 2 and 3

Analytical biochemistry, 2009-12, Vol.395 (2), p.189-194

2009

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Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

ACS chemical biology, 2012-05, Vol.7 (5), p.805-810

2012

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Aus zwei mach eins – von der Wirkstoffforschung ins Schülerlabor

Nachrichten aus der Chemie, 2023-07, Vol.71 (7-08), p.15-19

2023

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Pan-Specific Inhibitor of the Polo-Box Domains of Polo-like Kinases Arrests Cancer Cells in Mitosis

Chembiochem : a European journal of chemical biology, 2009-05, Vol.10 (7), p.1145-1148

2009

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Selective Inhibition of c-Myc/Max Dimerization by a Pyrazolo[1,5-a]pyrimidine

ChemMedChem, 2007-05, Vol.2 (5), p.627-630

2007

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A high-throughput assay for signal transducer and activator of transcription 5b based on fluorescence polarization

Analytical biochemistry, 2008-04, Vol.375 (2), p.249-254

2008

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Inhibitors of the Polo-Box Domain of Polo-Like Kinase 1

The hydrophobically-tagged MDM2-p53 interaction inhibitor Nutlin-3a-HT is more potent against tumor cells than Nutlin-3a

Polymer Nanocomposite Ultrafiltration Membranes: The Influence of Polymeric Additive, Dispersion Quality and Particle Modification on the Integration of Zinc Oxide Nanoparticles into Polyvinylidene Difluoride Membranes

Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b

iSPAAC: Isomer‐Free Generation of a Bcl‐xL‐Inhibitor in Living Cells

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5

Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells

A High-Throughput Fluorescence Polarization-Based Assay for the SH2 Domain of STAT4

GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis

Polo-Box Domain Inhibitor Poloxin Activates the Spindle Assembly Checkpoint and Inhibits Tumor Growth in Vivo

A high-throughput assay based on fluorescence polarization for inhibitors of the polo-box domain of polo-like kinase 1

MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

Inhibition of Protein–Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases

A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3

Mit organischen Substanzen hemmen

Die Hemmung von Protein‐Protein‐Wechselwirkungen: neue Ansätze zur Entwicklung von Wirkstoffen gegen Tropenkrankheiten

Development of high-throughput assays based on fluorescence polarization for inhibitors of the polo-box domains of polo-like kinases 2 and 3

Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

Aus zwei mach eins – von der Wirkstoffforschung ins Schülerlabor

Pan-Specific Inhibitor of the Polo-Box Domains of Polo-like Kinases Arrests Cancer Cells in Mitosis

Selective Inhibition of c-Myc/Max Dimerization by a Pyrazolo[1,5-a]pyrimidine

A high-throughput assay for signal transducer and activator of transcription 5b based on fluorescence polarization

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