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Role of protein kinase CK2 in antitumor drug resistance

Journal of experimental & clinical cancer research, 2019-07, Vol.38 (1), p.287-287, Article 287

2019

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Addiction to protein kinase CK2: A common denominator of diverse cancer cells?

Biochimica et biophysica acta, 2010-03, Vol.1804 (3), p.499-504

2010

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Protein kinase CK2: a potential therapeutic target for diverse human diseases

Signal transduction and targeted therapy, 2021-05, Vol.6 (1), p.183-183, Article 183

2021

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Casein kinase: the triple meaning of a misnomer

Biochemical journal, 2014-06, Vol.460 (2), p.141-156

2014

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The selectivity of inhibitors of protein kinase CK2: an update

Biochemical journal, 2008-11, Vol.415 (3), p.353-365

2008

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Targeting CK2 in cancer: a valuable strategy or a waste of time?

Cell death discovery, 2021-10, Vol.7 (1), p.325-325, Article 325

2021

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Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells

PloS one, 2020-01, Vol.15 (1), p.e0227340

2020

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A novel class of selective CK2 inhibitors targeting its open hinge conformation

European journal of medicinal chemistry, 2020-06, Vol.195, p.112267-112267, Article 112267

2020

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Helicobacter pylori periplasmic receptor CeuE (HP1561) modulates its nickel affinity via organic metallophores

Molecular microbiology, 2014-02, Vol.91 (4), p.724-735

2014

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Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

Biochemical journal, 2009-07, Vol.421 (3), p.387-395

2009

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Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

Biochemical journal, 2002-05, Vol.364 (Pt 1), p.41-47

2002

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The importance of negative determinants as modulators of CK2 targeting. The lesson of Akt2 S131

PloS one, 2018-03, Vol.13 (3), p.e0193479-e0193479

2018

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Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity

Biochemical journal, 2015-11, Vol.471 (3), p.415-430

2015

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Protein Kinase CK2 Protects Multiple Myeloma Cells from ER Stress-Induced Apoptosis and from the Cytotoxic Effect of HSP90 Inhibition through Regulation of the Unfolded Protein Response

Clinical cancer research, 2012-04, Vol.18 (7), p.1888-1900

2012

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Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells

PloS one, 2012-11, Vol.7 (11), p.e49193

2012

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A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia

Neurobiology of disease, 2018-07, Vol.115, p.157-166

2018

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The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells

Oncogenesis (New York, NY), 2019-10, Vol.8 (11), p.61-12, Article 61

2019

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Targeting Protein Kinase CK2: Evaluating CX-4945 Potential for GL261 Glioblastoma Therapy in Immunocompetent Mice

Pharmaceuticals (Basel, Switzerland), 2017-02, Vol.10 (1), p.24

2017

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Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

BMC cancer, 2010-08, Vol.10 (1), p.440-440, Article 440

2010

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Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells

Cellular and molecular life sciences : CMLS, 2009-10, Vol.66 (20), p.3363-3373

2009

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Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2)

PloS one, 2014-02, Vol.9 (2), p.e89176-e89176

2014

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Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6239-6247

2004

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Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (‘casein kinase-2’)

FEBS letters, 2001-05, Vol.496 (1), p.44-48

2001

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Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

Science advances, 2022-09, Vol.8 (35), p.eabo1215-eabo1215

2022

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Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL

PloS one, 2010-10, Vol.5 (10), p.e13552-e13552

2010

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Role of protein kinase CK2 in antitumor drug resistance

Addiction to protein kinase CK2: A common denominator of diverse cancer cells?

Protein kinase CK2: a potential therapeutic target for diverse human diseases

Casein kinase: the triple meaning of a misnomer

The selectivity of inhibitors of protein kinase CK2: an update

Targeting CK2 in cancer: a valuable strategy or a waste of time?

Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells

A novel class of selective CK2 inhibitors targeting its open hinge conformation

Helicobacter pylori periplasmic receptor CeuE (HP1561) modulates its nickel affinity via organic metallophores

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

The importance of negative determinants as modulators of CK2 targeting. The lesson of Akt2 S131

Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity

Protein Kinase CK2 Protects Multiple Myeloma Cells from ER Stress-Induced Apoptosis and from the Cytotoxic Effect of HSP90 Inhibition through Regulation of the Unfolded Protein Response

Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells

A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia

The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells

Targeting Protein Kinase CK2: Evaluating CX-4945 Potential for GL261 Glioblastoma Therapy in Immunocompetent Mice

Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells

Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2)

Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (‘casein kinase-2’)

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL

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