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High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

The American journal of clinical nutrition, 2015-03, Vol.101 (3), p.646-658

2015

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Epigenome-Wide Association of Liver Methylation Patterns and Complex Metabolic Traits in Mice

Cell metabolism, 2015-06, Vol.21 (6), p.905-917

2015

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Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Sex-Specific Gene Expression in Brain of Young Mice and Embryos

Nutrients, 2022-03, Vol.14 (5), p.1051

2022

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Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR)

Thrombosis and haemostasis, 1997, Vol.78 (1), p.523-526

Rozen, R

1997

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Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

The Journal of nutrition, 2010-10, Vol.140 (10), p.1736-1741

2010

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Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

Nutrients, 2020-06, Vol.12 (6), p.1716

2020

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High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection

PloS one, 2015-11, Vol.10 (11), p.e0143738-e0143738

2015

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Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice

Nutrients, 2021-12, Vol.14 (1), p.127

2021

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Effects of Common Polymorphisms on the Properties of Recombinant Human Methylenetetrahydrofolate Reductase

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14853-14858

2001

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Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study

American journal of obstetrics and gynecology, 2009-02, Vol.200 (2), p.151.e1-151.e9

2009

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High intake of folic acid disrupts embryonic development in mice

Birth defects research. A Clinical and molecular teratology, 2011-01, Vol.91 (1), p.8-19

2011

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Endoplasmic Reticulum Stress Increases the Expression of Methylenetetrahydrofolate Reductase through the IRE1 Transducer

The Journal of biological chemistry, 2008-02, Vol.283 (6), p.3151-3160

2008

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Strain-Specific Defects in Testicular Development and Sperm Epigenetic Patterns in 5,10-Methylenetetrahydrofolate Reductase-Deficient Mice

Endocrinology (Philadelphia), 2010-07, Vol.151 (7), p.3363-3373

2010

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Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation

Biology of reproduction, 2005-03, Vol.72 (3), p.667-677

2005

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Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase

Molecular genetics and metabolism, 2007-05, Vol.91 (1), p.85-97

2007

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Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations

Circulation (New York, N.Y.), 1996, Vol.93 (1), p.7-9

1996

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Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Journal of cellular biochemistry, 2008-10, Vol.105 (2), p.467-476

2008

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Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase

Anti-cancer drugs, 2009-10, Vol.20 (9), p.787-793

2009

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Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption

American journal of obstetrics and gynecology, 2007-10, Vol.197 (4), p.385.e1-385.e7

2007

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Antisense Inhibition of Methylenetetrahydrofolate Reductase Reduces Cancer Cell Survival In vitro and Tumor Growth In vivo

Clinical cancer research, 2005-03, Vol.11 (5), p.2047-2052

2005

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Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: Risk of placental abruption

Molecular genetics and metabolism, 2007-05, Vol.91 (1), p.104-110

2007

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Methylenetetrahydrofolate Reductase Polymorphism, Plasma Folate, Homocysteine, and Risk of Myocardial Infarction in US Physicians

Circulation (New York, N.Y.), 1996-11, Vol.94 (10), p.2410-2416

1996

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Socio-economic disparities in preterm birth: causal pathways and mechanisms

Paediatric and perinatal epidemiology, 2001-07, Vol.15 (s2), p.104-123

2001

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A Polymorphism of the Methionine Synthase Gene: Association with Plasma Folate, Vitamin B12, Homocyst(e)ine, and Colorectal Cancer Risk

Cancer epidemiology, biomarkers & prevention, 1999-09, Vol.8 (9), p.825-829

1999

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Risk of congenital heart defects is influenced by genetic variation in folate metabolism

Cardiology in the young, 2013-02, Vol.23 (1), p.89-98

2013

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High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

Epigenome-Wide Association of Liver Methylation Patterns and Complex Metabolic Traits in Mice

Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Sex-Specific Gene Expression in Brain of Young Mice and Embryos

Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR)

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection

Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice

Effects of Common Polymorphisms on the Properties of Recombinant Human Methylenetetrahydrofolate Reductase

Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study

High intake of folic acid disrupts embryonic development in mice

Endoplasmic Reticulum Stress Increases the Expression of Methylenetetrahydrofolate Reductase through the IRE1 Transducer

Strain-Specific Defects in Testicular Development and Sperm Epigenetic Patterns in 5,10-Methylenetetrahydrofolate Reductase-Deficient Mice

Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation

Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase

Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption

Antisense Inhibition of Methylenetetrahydrofolate Reductase Reduces Cancer Cell Survival In vitro and Tumor Growth In vivo

Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: Risk of placental abruption

Methylenetetrahydrofolate Reductase Polymorphism, Plasma Folate, Homocysteine, and Risk of Myocardial Infarction in US Physicians

Socio-economic disparities in preterm birth: causal pathways and mechanisms

A Polymorphism of the Methionine Synthase Gene: Association with Plasma Folate, Vitamin B12, Homocyst(e)ine, and Colorectal Cancer Risk

Risk of congenital heart defects is influenced by genetic variation in folate metabolism

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