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Conformation and bioactivity. Design and discovery of novel antihypertensive drugs

Current topics in medicinal chemistry, 2004-01, Vol.4 (4), p.385-401

2004

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Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy

Journal of pharmaceutical and biomedical analysis, 2003-04, Vol.31 (5), p.833-844

2003

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An Effort To Understand the Molecular Basis of Hypertension through the Study of Conformational Analysis of Losartan and Sarmesin Using a Combination of Nuclear Magnetic Resonance Spectroscopy and Theoretical Calculations

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1714-1722

1999

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Design and synthesis of small semi-mimetic peptides with immunomodulatory activity based on myelin basic protein (MBP)

Amino acids, 1998-01, Vol.14 (4), p.333-341

1998

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A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity

Amino acids, 1998-01, Vol.15 (3), p.211-220

1998

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Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges: Role of C-Terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2627-2633

2002

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The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II

Bioorganic & medicinal chemistry, 2000, Vol.8 (1), p.1-10

2000

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Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists

Bioorganic & medicinal chemistry, 2001-06, Vol.9 (6), p.1639-1647

2001

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Conformational and biological studies for a pair of novel synthetic AT 1 antagonists: stereoelectronic requirements for antihypertensive efficacy

Journal of pharmaceutical and biomedical analysis, 2003, Vol.31 (5), p.833-844

2003

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Structural comparison between type I and type II antagonists : Possible implications in the drug design of AT1 antagonists

Bioorganic & medicinal chemistry letters, 2000-04, Vol.10 (8), p.755-758

2000

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Conformational and biological studies for a pair of novel synthetic AT sub(1) antagonists: stereoelectronic requirements for antihypertensive efficacy

Journal of pharmaceutical and biomedical analysis, 2003-04, Vol.31 (5), p.833-844

2003

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Fluid balance concepts in medicine: Principles and practice

World journal of nephrology, 2018-01, Vol.7 (1), p.1-28

2018

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Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancers

Cell, 2015-02, Vol.160 (5), p.913-927

2015

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Rediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases

Frontiers in medicine, 2017-06, Vol.4, p.73-73

2017

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Intertwining noncommutativity with gravity and particle physics

The European physical journal. ST, Special topics, 2023-12, Vol.232 (23-24), p.3607-3624

2023

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Gauge theoretic approach to (ordinary) gravity and its fuzzy extensions in three and four dimensions

Journal of physics. A, Mathematical and theoretical, 2022-12, Vol.55 (49), p.493001

2022

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Beta-2 microglobulin clearance in high-flux dialysis and convective dialysis modalities: a meta-analysis of published studies

Nephrology, dialysis, transplantation, 2018-06, Vol.33 (6), p.1025-1039

2018

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Source‐Related Variability of Site Response in the Mygdonian Basin (Greece) from Accelerometric Recordings and 3D Numerical Simulations

Bulletin of the Seismological Society of America, 2017-04, Vol.107 (2), p.787-808

2017

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Imaging the Sources of the March 2021 Seismic Sequence in Thessaly Basin (Central Greece) from Kinematic Slip Inversion and Backprojection of Waveform Envelopes

Bulletin of the Seismological Society of America, 2024-04, Vol.114 (2), p.758-774

2024

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Pseudohyponatremia: Mechanism, Diagnosis, Clinical Associations and Management

Journal of clinical medicine, 2023-06, Vol.12 (12), p.4076

2023

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Hypernatremia in Hyperglycemia: Clinical Features and Relationship to Fractional Changes in Body Water and Monovalent Cations during Its Development

Journal of clinical medicine, 2024-04, Vol.13 (7), p.1957

2024

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581P Homologous recombination deficiency (HRD) in 543 ovarian cancer samples: A single center hands-on experience

Annals of oncology, 2022-09, Vol.33, p.S813

2022

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Conformation and bioactivity. Design and discovery of novel antihypertensive drugs

Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy

An Effort To Understand the Molecular Basis of Hypertension through the Study of Conformational Analysis of Losartan and Sarmesin Using a Combination of Nuclear Magnetic Resonance Spectroscopy and Theoretical Calculations

Design and synthesis of small semi-mimetic peptides with immunomodulatory activity based on myelin basic protein (MBP)

A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity

Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges: Role of C-Terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists

The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II

Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists

Conformational and biological studies for a pair of novel synthetic AT 1 antagonists: stereoelectronic requirements for antihypertensive efficacy

Structural comparison between type I and type II antagonists : Possible implications in the drug design of AT1 antagonists

Conformational and biological studies for a pair of novel synthetic AT sub(1) antagonists: stereoelectronic requirements for antihypertensive efficacy

Fluid balance concepts in medicine: Principles and practice

Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancers

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Rediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

Intertwining noncommutativity with gravity and particle physics

Gauge theoretic approach to (ordinary) gravity and its fuzzy extensions in three and four dimensions

Beta-2 microglobulin clearance in high-flux dialysis and convective dialysis modalities: a meta-analysis of published studies

Source‐Related Variability of Site Response in the Mygdonian Basin (Greece) from Accelerometric Recordings and 3D Numerical Simulations

Correction to: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

Imaging the Sources of the March 2021 Seismic Sequence in Thessaly Basin (Central Greece) from Kinematic Slip Inversion and Backprojection of Waveform Envelopes

Pseudohyponatremia: Mechanism, Diagnosis, Clinical Associations and Management

Hypernatremia in Hyperglycemia: Clinical Features and Relationship to Fractional Changes in Body Water and Monovalent Cations during Its Development

581P Homologous recombination deficiency (HRD) in 543 ovarian cancer samples: A single center hands-on experience

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