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Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2

Immunity (Cambridge, Mass.), 2020-04, Vol.52 (4), p.591-605.e6

2020

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Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection

Molecular therapy, 2013-05, Vol.21 (5), p.973-985

2013

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In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma

Molecular therapy, 2014-01, Vol.22 (1), p.81-91

2014

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Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

Molecular therapy. Nucleic acids, 2012-01, Vol.1 (1), p.e7-e7, Article e7

2012

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Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy

Molecular therapy. Nucleic acids, 2017-09, Vol.8, p.1-12

2017

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Activity of nucleic acid polymers in rodent models of HBV infection

Antiviral research, 2018-01, Vol.149, p.26-33

2018

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RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy

Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3952-3962

2009

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cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Nature (London), 2013-06, Vol.498 (7454), p.380-384

2013

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Characterization of side reactions during the annealing of small interfering RNAs

Analytical biochemistry, 2011-07, Vol.414 (1), p.47-57

2011

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RNAi-mediated gene silencing in non-human primates

Nature, 2006-05, Vol.441 (7089), p.111-114

2006

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Ag+‑Mediated DNA Base Pairing: Extraordinarily Stable Pyrrolo-dC–Pyrrolo-dC Pairs Binding Two Silver Ions

Journal of organic chemistry, 2013-09, Vol.78 (18), p.9457-9463

2013

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Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

Molecular therapy, 2009-05, Vol.17 (5), p.872-879

2009

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Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (33), p.11915-11920

2008

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Silver Arrays Inside DNA Duplexes Constructed from Silver(I)-Mediated Pyrrolo-dC-Pyrrolo-dC Base Pairs

ChemPlusChem (Weinheim, Germany), 2014-07, Vol.79 (7), p.914-918

2014

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Characterization of small interfering RNA by non-denaturing ion-pair reversed-phase liquid chromatography

Journal of Chromatography A, 2011-08, Vol.1218 (33), p.5609-5617

2011

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Immune sensing of synthetic, bacterial and protozoan RNA by TLR8 requires coordinated processing of RNA substrates by RNaseT2 and RNase2

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.226-226.30

2020

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Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

Cell host & microbe, 2008-09, Vol.4 (3), p.271-282

2008

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2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)

Bioanalysis, 2018-11, Vol.10 (22), p.1781-1801

2018

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Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection

PLoS pathogens, 2008-11, Vol.4 (11), p.e1000201-e1000201

2008

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Purification of small interfering RNA using nondenaturing anion-exchange chromatography

Nucleic acid therapeutics, 2011-12, Vol.21 (6), p.383-393

2011

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Aminomodified Nucleobases: Functionalized Nucleoside Triphosphates Applicable for SELEX

Bioconjugate chemistry, 2003-09, Vol.14 (5), p.919-926

2003

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Abstract 583: RNAi Therapeutics For The Lowering Of Cholesterol

Circulation (New York, N.Y.), 2007-10, Vol.116 (suppl_16)

2007

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Toxicity of functional nano-micro zinc oxide tetrapods: impact of cell culture conditions, cellular age and material properties

PloS one, 2014-01, Vol.9 (1), p.e84983

2014

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Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

BMJ open, 2018-10, Vol.8 (10), p.e023609-e023609

2018

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Rosetta in CASP4: Progress in ab initio protein structure prediction

Proteins, structure, function, and bioinformatics, 2001, Vol.45 (S5), p.119-126

2001

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Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2

Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection

In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma

Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy

Activity of nucleic acid polymers in rodent models of HBV infection

RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Characterization of side reactions during the annealing of small interfering RNAs

RNAi-mediated gene silencing in non-human primates

Ag+‑Mediated DNA Base Pairing: Extraordinarily Stable Pyrrolo-dC–Pyrrolo-dC Pairs Binding Two Silver Ions

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Silver Arrays Inside DNA Duplexes Constructed from Silver(I)-Mediated Pyrrolo-dC-Pyrrolo-dC Base Pairs

Characterization of small interfering RNA by non-denaturing ion-pair reversed-phase liquid chromatography

Immune sensing of synthetic, bacterial and protozoan RNA by TLR8 requires coordinated processing of RNA substrates by RNaseT2 and RNase2

Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)

Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection

Purification of small interfering RNA using nondenaturing anion-exchange chromatography

Aminomodified Nucleobases: Functionalized Nucleoside Triphosphates Applicable for SELEX

Abstract 583: RNAi Therapeutics For The Lowering Of Cholesterol

Toxicity of functional nano-micro zinc oxide tetrapods: impact of cell culture conditions, cellular age and material properties

Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

Rosetta in CASP4: Progress in ab initio protein structure prediction

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