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Raf kinases: Oncogenesis and drug discovery

International journal of cancer, 2006-11, Vol.119 (10), p.2261-2271

2006

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Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration

Nature cell biology, 2005-08, Vol.7 (8), p.837-843

2005

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Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers

Oncoimmunology, 2021-01, Vol.10 (1), p.1885778-1885778

2021

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MYC is a metastasis gene for non-small-cell lung cancer

PloS one, 2009-06, Vol.4 (6), p.e6029-e6029

2009

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Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

Molecular and Cellular Biology, 2010-10, Vol.30 (19), p.4698-4711

2010

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Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum

PloS one, 2013-03, Vol.8 (3), p.e58259

2013

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Oncogene-induced plasticity and cancer stem cells

Cell cycle (Georgetown, Tex.), 2008-01, Vol.7 (1), p.45-51

2008

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RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development

PloS one, 2010-12, Vol.5 (12), p.e14435-e14435

2010

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In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B

PloS one, 2015-02, Vol.10 (2), p.e0117794-e0117794

2015

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MAPKAP Kinase 3pK Phosphorylates and Regulates Chromatin Association of the Polycomb Group Protein Bmi1

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5178-5187

2005

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Non‐invasive lung cancer diagnosis by detection of GATA6 and NKX2‐1 isoforms in exhaled breath condensate

EMBO molecular medicine, 2016-12, Vol.8 (12), p.1380-1389

2016

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Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression

PloS one, 2010-03, Vol.5 (3), p.e9572-e9572

2010

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Ras oncogenes and their downstream targets

Biochimica et biophysica acta, 2007-08, Vol.1773 (8), p.1177-1195

2007

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Phospho-ERK Staining Is a Poor Indicator of the Mutational Status of BRAF and NRAS in Human Melanoma

Journal of investigative dermatology, 2008-08, Vol.128 (8), p.2003-2012

2008

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Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site

Nature (London), 2015-12, Vol.528 (7583), p.570-574

2015

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Disruption of Tumor Cell Adhesion Promotes Angiogenic Switch and Progression to Micrometastasis in RAF-Driven Murine Lung Cancer

Cancer cell, 2007-08, Vol.12 (2), p.145-159

2007

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E-cadherin Controls Bronchiolar Progenitor Cells and Onset of Preneoplastic Lesions in Mice

Neoplasia (New York, N.Y.), 2012-12, Vol.14 (12), p.1164-IN31

2012

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Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria

Cell, 1996-11, Vol.87 (4), p.629-638

1996

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MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma

Molecular cancer research, 2013-02, Vol.11 (2), p.161-172

2013

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Conditional Expression of Oncogenic C-RAF in Mouse Pulmonary Epithelial Cells Reveals Differential Tumorigenesis and Induction of Autophagy Leading to Tumor Regression

Neoplasia (New York, N.Y.), 2011-11, Vol.13 (11), p.1005-IN17

2011

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A-RAF kinase functions in ARF6 regulated endocytic membrane traffic

PloS one, 2009-02, Vol.4 (2), p.e4647-e4647

2009

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Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer

PloS one, 2009-01, Vol.4 (1), p.e4230

2009

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Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk

Science translational medicine, 2017-11, Vol.9 (416)

2017

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Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer

Oncotarget, 2018-01, Vol.9 (5), p.6518-6535

2018

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Reversible Membrane Interaction of BAD Requires two C-terminal Lipid Binding Domains in Conjunction with 14-3-3 Protein Binding

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.17321-17336

2006

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Raf kinases: Oncogenesis and drug discovery

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration

Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers

MYC is a metastasis gene for non-small-cell lung cancer

Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum

Oncogene-induced plasticity and cancer stem cells

RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development

In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B

MAPKAP Kinase 3pK Phosphorylates and Regulates Chromatin Association of the Polycomb Group Protein Bmi1

Non‐invasive lung cancer diagnosis by detection of GATA6 and NKX2‐1 isoforms in exhaled breath condensate

Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression

Ras oncogenes and their downstream targets

Phospho-ERK Staining Is a Poor Indicator of the Mutational Status of BRAF and NRAS in Human Melanoma

Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site

Disruption of Tumor Cell Adhesion Promotes Angiogenic Switch and Progression to Micrometastasis in RAF-Driven Murine Lung Cancer

E-cadherin Controls Bronchiolar Progenitor Cells and Onset of Preneoplastic Lesions in Mice

Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria

MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma

Conditional Expression of Oncogenic C-RAF in Mouse Pulmonary Epithelial Cells Reveals Differential Tumorigenesis and Induction of Autophagy Leading to Tumor Regression

A-RAF kinase functions in ARF6 regulated endocytic membrane traffic

Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer

Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk

Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer

Reversible Membrane Interaction of BAD Requires two C-terminal Lipid Binding Domains in Conjunction with 14-3-3 Protein Binding

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