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Blockade of orexin receptors in the infralimbic cortex prevents stress‐induced reinstatement of alcohol‐seeking behaviour in alcohol‐dependent rats

British journal of pharmacology, 2023-06, Vol.180 (11), p.1500-1515

2023

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COX‐2 Inhibition Antagonizes Intra‐Accumbens 2‐Arachidonoylglycerol–Mediated Reduction in Ethanol Self‐Administration in Rats

Alcoholism, clinical and experimental research, 2020-11, Vol.44 (11), p.2158-2165

2020

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Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Addiction biology, 2020-09, Vol.25 (5), p.e12813-n/a

2020

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Ethanol‐induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice

Addiction biology, 2019-11, Vol.24 (6), p.1204-1215

2019

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MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats

Addiction biology, 2015-07, Vol.20 (4), p.643-651

2015

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Phosphorylation of calcium/calmodulin‐dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol‐induced cognitive inflexibility

Addiction biology, 2018-09, Vol.23 (5), p.1117-1129

2018

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Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine‐induced dopamine release in the mouse nucleus accumbens

Addiction biology, 2018-03, Vol.23 (2), p.723-734

2018

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Targeting the orexin system for prescription opioid use disorder: Orexin-1 receptor blockade prevents oxycodone taking and seeking in rats

Neuropharmacology, 2020-03, Vol.164, p.107906-107906, Article 107906

2020

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Understanding the Role of Orexin Neuropeptides in Drug Addiction: Preclinical Studies and Translational Value

Frontiers in behavioral neuroscience, 2022-01, Vol.15, p.787595-787595

2022

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Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal

Addiction biology, 2013-05, Vol.18 (3), p.467-479

2013

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Possible Role of CRF‐Hcrt Interaction in the Infralimbic Cortex in the Emergence and Maintenance of Compulsive Alcohol‐Seeking Behavior

Alcoholism, clinical and experimental research, 2020-02, Vol.44 (2), p.354-367

2020

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Behavioral and Functional Evidence of Metabotropic Glutamate Receptor 2/3 and Metabotropic Glutamate Receptor 5 Dysregulation in Cocaine-Escalated Rats: Factor in the Transition to Dependence

Biological psychiatry (1969), 2010-08, Vol.68 (3), p.240-248

2010

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Orexin-A/Hypocretin-1 Mediates Cocaine-Seeking Behavior in the Posterior Paraventricular Nucleus of the Thalamus via Orexin/Hypocretin Receptor-2

The Journal of pharmacology and experimental therapeutics, 2016-11, Vol.359 (2), p.273-279

2016

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Blockade of Orexin Receptors in the Posterior Paraventricular Nucleus of the Thalamus Prevents Stress-Induced Reinstatement of Reward-Seeking Behavior in Rats With a History of Ethanol Dependence

Frontiers in integrative neuroscience, 2020-11, Vol.14, p.599710-599710

2020

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Cocaine-Seeking Behavior Induced by Orexin A Administration in the Posterior Paraventricular Nucleus of the Thalamus Is Not Long-Lasting: Neuroadaptation of the Orexin System During Cocaine Abstinence

Frontiers in behavioral neuroscience, 2021-02, Vol.15, p.620868-620868

2021

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Differential role of hypothalamic orexin/hypocretin neurons in reward seeking motivated by cocaine versus palatable food

Addiction biology, 2018-01, Vol.23 (1), p.6-15

2018

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Drug Seeking and Relapse: New Evidence of a Role for Orexin and Dynorphin Co-transmission in the Paraventricular Nucleus of the Thalamus

Frontiers in neurology, 2018-08, Vol.9, p.720-720

2018

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Exploring Sex Differences in the Attenuation of Ethanol Drinking by Naltrexone in Dependent Rats During Early and Protracted Abstinence

Alcoholism, clinical and experimental research, 2018-12, Vol.42 (12), p.2466-2478

2018

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Cebranopadol Blocks the Escalation of Cocaine Intake and Conditioned Reinstatement of Cocaine Seeking in Rats

The Journal of pharmacology and experimental therapeutics, 2017-09, Vol.362 (3), p.378-384

2017

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LY2444296, a κ-opioid receptor antagonist, selectively reduces alcohol drinking in male and female Wistar rats with a history of alcohol dependence

Scientific reports, 2024-03, Vol.14 (1), p.5804-5804, Article 5804

2024

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Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand

Addiction biology, 2017-07, Vol.22 (4), p.923-932

2017

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N-(2-methyl-6-benzoxazolyl)-N′-1,5-naphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking

Addiction biology, 2014-03, Vol.19 (2), p.233-236

2014

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Stimuli Linked to Ethanol Availability Activate Hypothalamic CART and Orexin Neurons in a Reinstatement Model of Relapse

Biological psychiatry (1969), 2008-01, Vol.63 (2), p.152-157

2008

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Role for Hypocretin in Mediating Stress-Induced Reinstatement of Cocaine-Seeking Behavior

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (52), p.19168-19173

2005

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Targeting the Orexin System for Prescription Opioid Use Disorder

Brain sciences, 2020-04, Vol.10 (4), p.226

2020

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Blockade of orexin receptors in the infralimbic cortex prevents stress‐induced reinstatement of alcohol‐seeking behaviour in alcohol‐dependent rats

COX‐2 Inhibition Antagonizes Intra‐Accumbens 2‐Arachidonoylglycerol–Mediated Reduction in Ethanol Self‐Administration in Rats

Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Ethanol‐induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice

MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats

Phosphorylation of calcium/calmodulin‐dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol‐induced cognitive inflexibility

Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine‐induced dopamine release in the mouse nucleus accumbens

Targeting the orexin system for prescription opioid use disorder: Orexin-1 receptor blockade prevents oxycodone taking and seeking in rats

Understanding the Role of Orexin Neuropeptides in Drug Addiction: Preclinical Studies and Translational Value

Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal

Possible Role of CRF‐Hcrt Interaction in the Infralimbic Cortex in the Emergence and Maintenance of Compulsive Alcohol‐Seeking Behavior

Behavioral and Functional Evidence of Metabotropic Glutamate Receptor 2/3 and Metabotropic Glutamate Receptor 5 Dysregulation in Cocaine-Escalated Rats: Factor in the Transition to Dependence

Orexin-A/Hypocretin-1 Mediates Cocaine-Seeking Behavior in the Posterior Paraventricular Nucleus of the Thalamus via Orexin/Hypocretin Receptor-2

Blockade of Orexin Receptors in the Posterior Paraventricular Nucleus of the Thalamus Prevents Stress-Induced Reinstatement of Reward-Seeking Behavior in Rats With a History of Ethanol Dependence

Cocaine-Seeking Behavior Induced by Orexin A Administration in the Posterior Paraventricular Nucleus of the Thalamus Is Not Long-Lasting: Neuroadaptation of the Orexin System During Cocaine Abstinence

Differential role of hypothalamic orexin/hypocretin neurons in reward seeking motivated by cocaine versus palatable food

Drug Seeking and Relapse: New Evidence of a Role for Orexin and Dynorphin Co-transmission in the Paraventricular Nucleus of the Thalamus

Exploring Sex Differences in the Attenuation of Ethanol Drinking by Naltrexone in Dependent Rats During Early and Protracted Abstinence

Cebranopadol Blocks the Escalation of Cocaine Intake and Conditioned Reinstatement of Cocaine Seeking in Rats

LY2444296, a κ-opioid receptor antagonist, selectively reduces alcohol drinking in male and female Wistar rats with a history of alcohol dependence

Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand

N-(2-methyl-6-benzoxazolyl)-N′-1,5-naphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking

Stimuli Linked to Ethanol Availability Activate Hypothalamic CART and Orexin Neurons in a Reinstatement Model of Relapse

Role for Hypocretin in Mediating Stress-Induced Reinstatement of Cocaine-Seeking Behavior

Targeting the Orexin System for Prescription Opioid Use Disorder

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