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Macrocycles as protein-protein interaction inhibitors

Biochemical journal, 2017-03, Vol.474 (7), p.1109-1125

2017

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Cell-Penetrating Peptides Escape the Endosome by Inducing Vesicle Budding and Collapse

ACS chemical biology, 2020-09, Vol.15 (9), p.2485-2492

2020

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Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides

Biochemistry (Easton), 2016-05, Vol.55 (18), p.2601-2612

2016

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Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore

Chemical communications (Cambridge, England), 2015-02, Vol.51 (11), p.2162-2165

2015

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Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides

ACS combinatorial science, 2016-01, Vol.18 (1), p.75-85

2016

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Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery

Biochemistry (Easton), 2014-06, Vol.53 (24), p.4034-4046

2014

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Synthesis and screening of one-bead-one-compound cyclic peptide libraries

Methods in molecular biology (Clifton, N.J.), 2015-01, Vol.1248, p.39

2015

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Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization

Angewandte Chemie (International ed.), 2017-02, Vol.56 (6), p.1525-1529

International ed. in English, 2017

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High-Throughput Screening of One-Bead-One-Compound Libraries: Identification of Cyclic Peptidyl Inhibitors against Calcineurin/NFAT Interaction

ACS combinatorial science, 2011-09, Vol.13 (5), p.537-546

2011

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The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders

Molecular therapy. Nucleic acids, 2023-09, Vol.33, p.273-285

2023

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Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

ACS omega, 2023-11, Vol.8 (45), p.42797-42802

2023

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Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides

Current opinion in chemical biology, 2017-06, Vol.38, p.80-86

2017

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Cell-Permeable Bicyclic Peptide Inhibitors against Intracellular Proteins

Journal of the American Chemical Society, 2014-07, Vol.136 (28), p.9830-9833

2014

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Cyclic Peptide Inhibitors of HIV-1 Capsid-Human Lysyl-tRNA Synthetase Interaction

ACS chemical biology, 2012-04, Vol.7 (4), p.761-769

2012

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Cyclic Cell‐Penetrating Peptides with Single Hydrophobic Groups

Chembiochem : a European journal of chemical biology, 2019-08, Vol.20 (16), p.2085-2088

2019

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The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons

The Journal of biological chemistry, 2013-07, Vol.288 (30), p.21955-21971

2013

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Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

Angewandte Chemie (International ed.), 2015-06, Vol.54 (26), p.7602-7606

International ed. in English, 2015

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Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide

Journal of medicinal chemistry, 2019-11, Vol.62 (22), p.10098-10107

2019

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Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library

Journal of the American Chemical Society, 2018-09, Vol.140 (38), p.12102-12110

2018

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Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

ACS chemical biology, 2013-02, Vol.8 (2), p.423-431

2013

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Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Angewandte Chemie (International ed.), 2015-05, Vol.54 (20), p.5874-5878

International ed. in English, 2015

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Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophoreElectronic supplementary information (ESI) available: Experimental details and additional data. See DOI: 10.1039/c4cc09441g

2015-01

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Non‐Peptidic Cell‐Penetrating Motifs for Mitochondrion‐Specific Cargo Delivery

Angewandte Chemie (International ed.), 2018-12, Vol.57 (52), p.17183-17188

International ed. in English, 2018

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The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease

The Journal of biological chemistry, 2013-07, Vol.288 (30), p.21955-21971

2013

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Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif

Bioorganic & medicinal chemistry, 2020-10, Vol.28 (20), p.115711-115711, Article 115711

2020

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Macrocycles as protein-protein interaction inhibitors

Cell-Penetrating Peptides Escape the Endosome by Inducing Vesicle Budding and Collapse

Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore

Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides

Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery

Synthesis and screening of one-bead-one-compound cyclic peptide libraries

Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization

High-Throughput Screening of One-Bead-One-Compound Libraries: Identification of Cyclic Peptidyl Inhibitors against Calcineurin/NFAT Interaction

The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders

Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides

Cell-Permeable Bicyclic Peptide Inhibitors against Intracellular Proteins

Cyclic Peptide Inhibitors of HIV-1 Capsid-Human Lysyl-tRNA Synthetase Interaction

Cyclic Cell‐Penetrating Peptides with Single Hydrophobic Groups

The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons

Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide

Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library

Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophoreElectronic supplementary information (ESI) available: Experimental details and additional data. See DOI: 10.1039/c4cc09441g

Non‐Peptidic Cell‐Penetrating Motifs for Mitochondrion‐Specific Cargo Delivery

The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease

Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif

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