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Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

Nature communications, 2021-12, Vol.12 (1), p.7171-7171, Article 7171

2021

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Journal of neuroinflammation, 2020-06, Vol.17 (1), p.192-192, Article 192

2020

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N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease

Journal of lipid research, 2019-08, Vol.60 (8), p.1410-1424

2019

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Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model

Scientific reports, 2024-01, Vol.14 (1), p.1042-1042, Article 1042

2024

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4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor

Journal of lipid research, 2021, Vol.62, p.100051, Article 100051

2021

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Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABAA Receptors

Molecular pharmacology, 2016-04, Vol.89 (4), p.399-406

2016

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Click Chemistry Reagent for Identification of Sites of Covalent Ligand Incorporation in Integral Membrane Proteins

Analytical chemistry (Washington), 2017-02, Vol.89 (4), p.2636-2644

2017

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Stereoselective Synthesis of the Side Chains of Mycolactones A and B Featuring Stepwise Double Substitutions of 1,1-Dibromo-1-alkenes

Angewandte Chemie (International ed.), 2006-04, Vol.45 (18), p.2916-2920

2006

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A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

Frontiers in neuroscience, 2018-12, Vol.12, p.923-923

2018

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Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes

Journal of the American Chemical Society, 2003-11, Vol.125 (45), p.13636-13637

2003

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Use of InCl3 as a Cocatalyst and a Cl2Pd(DPEphos)−P(2-Furyl)3 Catalyst System for One-Pot Hydrometalation−Cross-Coupling and Carbometalation−Cross-Coupling Tandem Processes

Organic letters, 2004-05, Vol.6 (10), p.1531-1534

2004

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A unified total synthesis route to 18-trideuterated and/or 19-trideuterated testosterone, androstenedione and progesterone

Steroids, 2024-05, Vol.205, p.109391-109391, Article 109391

2024

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Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications

RSC advances, 2023-12, Vol.13 (51), p.36484-36492

2023

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Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

Science (American Association for the Advancement of Science), 2022-09, Vol.377 (6612), p.1290-1298

2022

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Direct measurements of neurosteroid binding to specific sites on GABA A receptors

British journal of pharmacology, 2024-07

2024

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The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

Nature chemical biology, 2019-10, Vol.15 (10), p.975

2019

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A neuroactive steroid with a therapeutically interesting constellation of actions at GABA A and NMDA receptors

Neuropharmacology, 2021-02, Vol.183, p.108358

2021

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A neuroactive steroid with a therapeutically interesting constellation of actions at GABAA and NMDA receptors

Neuropharmacology, 2021-02, Vol.183, p.108358-108358, Article 108358

2021

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Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts

Investigative ophthalmology & visual science, 2019-08, Vol.60 (10), p.3320-3331

2019

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Identification of Neurosteroid Binding Sites on GABAA Receptors using Photolabeling with Mass Spectrometry

Biophysical journal, 2018-02, Vol.114 (3), p.25a-25a

2018

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Ethylene oligomerization by diimine iron(II) complexes/EAO

Journal of molecular catalysis. A, Chemical, 2000-10, Vol.160 (2), p.243-247

2000

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Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

Neuropharmacology, 2019-01, Vol.144, p.91-103

2019

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Ethylene oligomerization by cobalt(II) diimine complexes/EAO

Applied catalysis. A, General, 2001-02, Vol.209 (1-2), p.11-15

2001

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Validation of Trifluoromethylphenyl Diazirine Cholesterol Analogues As Cholesterol Mimetics and Photolabeling Reagents

ACS chemical biology, 2021-08, Vol.16 (8), p.1493-1507

2021

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Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α 1 β 2 γ 2L GABA A Receptors

Molecular pharmacology, 2016-04, Vol.89 (4), p.399-406

2016

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Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease

Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model

4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor

Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABAA Receptors

Click Chemistry Reagent for Identification of Sites of Covalent Ligand Incorporation in Integral Membrane Proteins

Stereoselective Synthesis of the Side Chains of Mycolactones A and B Featuring Stepwise Double Substitutions of 1,1-Dibromo-1-alkenes

A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes

Use of InCl3 as a Cocatalyst and a Cl2Pd(DPEphos)−P(2-Furyl)3 Catalyst System for One-Pot Hydrometalation−Cross-Coupling and Carbometalation−Cross-Coupling Tandem Processes

A unified total synthesis route to 18-trideuterated and/or 19-trideuterated testosterone, androstenedione and progesterone

Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications

Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

Direct measurements of neurosteroid binding to specific sites on GABA A receptors

The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

A neuroactive steroid with a therapeutically interesting constellation of actions at GABA A and NMDA receptors

A neuroactive steroid with a therapeutically interesting constellation of actions at GABAA and NMDA receptors

Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts

Identification of Neurosteroid Binding Sites on GABAA Receptors using Photolabeling with Mass Spectrometry

Ethylene oligomerization by diimine iron(II) complexes/EAO

Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

Ethylene oligomerization by cobalt(II) diimine complexes/EAO

Validation of Trifluoromethylphenyl Diazirine Cholesterol Analogues As Cholesterol Mimetics and Photolabeling Reagents

Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α 1 β 2 γ 2L GABA A Receptors

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