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Believe it or not: how much can we rely on published data on potential drug targets?

Nature reviews. Drug discovery, 2011-09, Vol.10 (9), p.712-712

2011

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Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

Journal for immunotherapy of cancer, 2023-11, Vol.11 (11), p.e007495

2023

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926 BAY 2965501: a highly selective DGK zeta inhibitor for cancer immunotherapy

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1029-A1029

2023

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A novel mouse model that closely mimics human uterine leiomyomas

Fertility and sterility, 2013-03, Vol.99 (3), p.927-935.e6

2013

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Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

PloS one, 2012-05, Vol.7 (5), p.e36125-e36125

2012

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Nervensonographie der unteren Extremitäten

Zeitschrift für Rheumatologie, 2024-02, Vol.83 (1), p.54-67

2024

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A genetics-led approach defines the drug target landscape of 30 immune-related traits

Nature genetics, 2019-07, Vol.51 (7), p.1082-1091

2019

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3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Experimental cell research, 2014-04, Vol.323 (1), p.131-143

2014

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Ultrasound of nerves of the lower extremities

Zeitschrift für Rheumatologie, 2024-02, Vol.83 (1), p.54-67

2024

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Caspase-8 and Apaf-1-independent Caspase-9 Activation in Sendai Virus-infected Cells

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.29817-29824

2002

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Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

Molecular cell, 2020-03, Vol.77 (6), p.1322-1339.e11

2020

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Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.601-612

2020

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Sendai Virus Infection Induces Apoptosis through Activation of Caspase-8 (FLICE) and Caspase-3 (CPP32)

Journal of Virology, 1999-01, Vol.73 (1), p.702-708

1999

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Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2‑d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.928-940

2019

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Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription

Molecular cell, 2021-06, Vol.81 (11), p.2495-2495

2021

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Abstract 1470: Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1470-1470

2021

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Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1288-1288

2019

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Abstract 5873: BAY-3827, a selective inhibitor of AMPK for the evaluation of the role of AMPK in Myc-dependent tumors

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5873-5873

2018

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Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells

The Journal of biological chemistry, 2016-05, Vol.291 (21), p.11252-11267

2016

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Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

Nature communications, 2011-07, Vol.2 (1), p.395, Article 395

2011

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Abstract ND04: BAY 2965501: A highly selective DGK- ζ inhibitor for cancer immuno-therapy with first-in-class potential

Cancer research (Chicago, Ill.), 2023-05, Vol.83 (7_Supplement), p.ND04-ND04

2023

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Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR) inhibitor BAY2416964

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (8_Supplement), p.CT276-CT276

2023

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Abstract 1036: Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1036-1036

2012

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Abstract 3833: Molecular mechanisms by which BAY 80-6946 induces apoptosis in breast tumor cells as single agent or in combination

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3833-3833

2011

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Informations- und Kommunikationsrecht: Lehrbuch für das gesamte IT-Recht

1st ed., 2018

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Believe it or not: how much can we rely on published data on potential drug targets?

Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

926 BAY 2965501: a highly selective DGK zeta inhibitor for cancer immunotherapy

A novel mouse model that closely mimics human uterine leiomyomas

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

Nervensonographie der unteren Extremitäten

A genetics-led approach defines the drug target landscape of 30 immune-related traits

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Ultrasound of nerves of the lower extremities

Caspase-8 and Apaf-1-independent Caspase-9 Activation in Sendai Virus-infected Cells

Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor

Sendai Virus Infection Induces Apoptosis through Activation of Caspase-8 (FLICE) and Caspase-3 (CPP32)

Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2‑d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription

Abstract 1470: Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions

Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor

Abstract 5873: BAY-3827, a selective inhibitor of AMPK for the evaluation of the role of AMPK in Myc-dependent tumors

Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

Abstract ND04: BAY 2965501: A highly selective DGK- ζ inhibitor for cancer immuno-therapy with first-in-class potential

Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR) inhibitor BAY2416964

Abstract 1036: Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

Abstract 3833: Molecular mechanisms by which BAY 80-6946 induces apoptosis in breast tumor cells as single agent or in combination

Informations- und Kommunikationsrecht: Lehrbuch für das gesamte IT-Recht

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