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Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

Chemical research in toxicology, 2020-03, Vol.33 (3), p.709-726

2020

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Interstrand DNA–DNA Cross-Link Formation Between Adenine Residues and Abasic Sites in Duplex DNA

Journal of the American Chemical Society, 2014-03, Vol.136 (9), p.3483-3490

2014

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Novel Processes Associated with the Repair of Interstrand Cross-Links Derived from Abasic Sites in Duplex DNA: Roles for the Base Excision Repair Glycosylase NEIL3 and the SRAP Protein HMCES

Chemical research in toxicology, 2024-02, Vol.37 (2), p.199-207

2024

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Ada protein– and sequence context–dependent mutagenesis of alkyl phosphotriester lesions in Escherichia coli cells

The Journal of biological chemistry, 2020-06, Vol.295 (26), p.8775-8783

2020

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Quantification of DNA Lesions Induced by 4‑(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Mammalian Cells

Chemical research in toxicology, 2019-04, Vol.32 (4), p.708-717

2019

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Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells

Nucleic acids research, 2017-06, Vol.45 (11), p.6486

2017

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The Impact of Minor-Groove N 2‑Alkyl-2′-deoxyguanosine Lesions on DNA Replication in Human Cells

ACS chemical biology, 2019-08, Vol.14 (8), p.1708-1716

2019

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A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites

DNA repair, 2017-04, Vol.52, p.1-11

2017

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Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA

Nucleic acids research, 2017-06, Vol.45 (11), p.6275

2017

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Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA

Chemical research in toxicology, 2021-04, Vol.34 (4), p.1124-1132

2021

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A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links

Biochemistry (Easton), 2016-12, Vol.55 (50), p.7033-7041

2016

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Chemical and structural characterization of interstrand cross-links formed between abasic sites and adenine residues in duplex DNA

Nucleic acids research, 2015-04, Vol.43 (7), p.3434

2015

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Characterization of Interstrand DNA–DNA Cross-Links Using the α‑Hemolysin Protein Nanopore

ACS nano, 2015-12, Vol.9 (12), p.11812-11819

2015

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Interstrand DNA Cross-Links Derived from Reaction of a 2‑Aminopurine Residue with an Abasic Site

ACS chemical biology, 2019-07, Vol.14 (7), p.1481-1489

2019

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On the Formation and Properties of Interstrand DNA–DNA Cross-Links Forged by Reaction of an Abasic Site with the Opposing Guanine Residue of 5′-CAp Sequences in Duplex DNA

Journal of the American Chemical Society, 2013-01, Vol.135 (3), p.1015-1025

2013

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The Impact of Minor-Groove N2-Alkyl-2'-deoxyguanosine Lesions on DNA Replication in Human Cells

ACS chemical biology, 2019-08, Vol.14 (8), p.1708-1716

2019

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Characterization of Interstrand DNA–DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ29 DNA Polymerase

Biochemistry (Easton), 2015-07, Vol.54 (27), p.4259-4266

2015

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Chemical Structure and Properties of Interstrand Cross-Links Formed by Reaction of Guanine Residues with Abasic Sites in Duplex DNA

Journal of the American Chemical Society, 2015-03, Vol.137 (11), p.3933-3945

2015

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Effective molarity in a nucleic acid-controlled reaction

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (11), p.2627-2630

2016

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Covalent Adduct Formation between the Antihypertensive Drug Hydralazine and Abasic Sites in Double- and Single-Stranded DNA

Chemical research in toxicology, 2014-12, Vol.27 (12), p.2113-2118

2014

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Effects of Local Sequence, Reaction Conditions, and Various Additives on the Formation and Stability of Interstrand Cross-Links Derived from the Reaction of an Abasic Site with an Adenine Residue in Duplex DNA

ACS omega, 2022-10, Vol.7 (41), p.36888-36901

2022

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Thiol-Activated DNA Damage by α-Bromo-2-cyclopentenone

Chemical research in toxicology, 2011-02, Vol.24 (2), p.217-228

2011

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IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

Neuron (Cambridge, Mass.), 2015-02, Vol.85 (3), p.519-533

2015

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Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

Neuron (Cambridge, Mass.), 2018-07, Vol.99 (1), p.64-82.e7

2018

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MEMOTE for standardized genome-scale metabolic model testing

Nature biotechnology, 2020-03, Vol.38 (3), p.272-276

2020

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Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

Interstrand DNA–DNA Cross-Link Formation Between Adenine Residues and Abasic Sites in Duplex DNA

Novel Processes Associated with the Repair of Interstrand Cross-Links Derived from Abasic Sites in Duplex DNA: Roles for the Base Excision Repair Glycosylase NEIL3 and the SRAP Protein HMCES

Ada protein– and sequence context–dependent mutagenesis of alkyl phosphotriester lesions in Escherichia coli cells

Quantification of DNA Lesions Induced by 4‑(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Mammalian Cells

Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells

The Impact of Minor-Groove N 2‑Alkyl-2′-deoxyguanosine Lesions on DNA Replication in Human Cells

A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites

Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA

Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA

A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links

Chemical and structural characterization of interstrand cross-links formed between abasic sites and adenine residues in duplex DNA

Characterization of Interstrand DNA–DNA Cross-Links Using the α‑Hemolysin Protein Nanopore

Interstrand DNA Cross-Links Derived from Reaction of a 2‑Aminopurine Residue with an Abasic Site

On the Formation and Properties of Interstrand DNA–DNA Cross-Links Forged by Reaction of an Abasic Site with the Opposing Guanine Residue of 5′-CAp Sequences in Duplex DNA

The Impact of Minor-Groove N2-Alkyl-2'-deoxyguanosine Lesions on DNA Replication in Human Cells

Characterization of Interstrand DNA–DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ29 DNA Polymerase

Chemical Structure and Properties of Interstrand Cross-Links Formed by Reaction of Guanine Residues with Abasic Sites in Duplex DNA

Effective molarity in a nucleic acid-controlled reaction

Covalent Adduct Formation between the Antihypertensive Drug Hydralazine and Abasic Sites in Double- and Single-Stranded DNA

Effects of Local Sequence, Reaction Conditions, and Various Additives on the Formation and Stability of Interstrand Cross-Links Derived from the Reaction of an Abasic Site with an Adenine Residue in Duplex DNA

Thiol-Activated DNA Damage by α-Bromo-2-cyclopentenone

IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

MEMOTE for standardized genome-scale metabolic model testing

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