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Functional characterization of a PROTAC directed against BRAF mutant V600E

Nature chemical biology, 2020-11, Vol.16 (11), p.1170

2020

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Advances in Solution- and Solid-Phase Synthesis toward the Generation of Natural Product-like Libraries

Chemical reviews, 2009-05, Vol.109 (5), p.1999-2060

2009

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Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11129-11147

2021

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Correction to “Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma”

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.886-887

2022

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Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (4), p.1385-1395

2011

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Size Reduction of CdSe/ZnS Quantum Dots by a Peptidic Amyloid Supergelator

ACS applied materials & interfaces, 2012-03, Vol.4 (3), p.1178-1181

2012

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The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia

Oncoimmunology, 2021-01, Vol.10 (1), p.1943234-1943234

2021

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Sorafenib as an Inhibitor of RUVBL2

Biomolecules (Basel, Switzerland), 2020-04, Vol.10 (4), p.605

2020

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The discovery of small molecule chemical probes of Bcl-XL and Mcl-1

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7443-7449

2008

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A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors

Neuro-oncology (Charlottesville, Va.), 2024-07

2024

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Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors

Nature communications, 2014-08, Vol.5 (1), p.4202-4202, Article 4202

2014

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Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells

Journal of molecular biology, 2021-11, Vol.433 (23), p.167294-167294, Article 167294

2021

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A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup ATRTs

Neuro-oncology (Charlottesville, Va.), 2024-07

2024

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Abstract 2377: Design, synthesis, and characterization of 4-aminopyrazole quinazolines as potent inhibitors of G protein-coupled receptor kinase GRK6 for the potential treatment of multiple myeloma

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2377-2377

2018

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PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma

Journal of translational medicine, 2016-03, Vol.14 (66), p.67, Article 67

2016

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Use of Kinase Inhibitors to Correct ΔF508-CFTR Function

Molecular & cellular proteomics, 2012-09, Vol.11 (9), p.745-757

2012

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Abstract 7: Discovery of OICR-10268: A potent and selective BCL6 inhibitor

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.7-7

2019

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The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7443-7449

2008

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One-pot construction of isoindolo[2,1- a]quinoline system

Tetrahedron letters, 2009-12, Vol.50 (48), p.6661-6664

2009

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COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS

Neuro-oncology (Charlottesville, Va.), 2014-07, Vol.16 (suppl 3), p.iii20-iii20

2014

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Abstract 4989: Selective inhibitors of the inositol-requiring enzyme 1 kinase domain

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4989-4989

2012

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The discovery of small molecule chemical probes of Bcl-X sub(L) and Mcl-1

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7443-7449

2008

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The discovery of small molecule chemical probes of Bcl-XLand Mcl-1

Bioorganic & medicinal chemistry, 2008, Vol.16 (15), p.7443-7449

2008

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Functional characterization of a PROTAC directed against BRAF mutant V600E

Advances in Solution- and Solid-Phase Synthesis toward the Generation of Natural Product-like Libraries

Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma

Correction to “Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma”

Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor

Size Reduction of CdSe/ZnS Quantum Dots by a Peptidic Amyloid Supergelator

The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia

Sorafenib as an Inhibitor of RUVBL2

The discovery of small molecule chemical probes of Bcl-XL and Mcl-1

A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors

Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells

A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup ATRTs

Abstract 2377: Design, synthesis, and characterization of 4-aminopyrazole quinazolines as potent inhibitors of G protein-coupled receptor kinase GRK6 for the potential treatment of multiple myeloma

PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma

Use of Kinase Inhibitors to Correct ΔF508-CFTR Function

Abstract 7: Discovery of OICR-10268: A potent and selective BCL6 inhibitor

The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1

One-pot construction of isoindolo[2,1- a]quinoline system

COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS

Abstract 4989: Selective inhibitors of the inositol-requiring enzyme 1 kinase domain

The discovery of small molecule chemical probes of Bcl-X sub(L) and Mcl-1

The discovery of small molecule chemical probes of Bcl-XLand Mcl-1

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