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Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

The Journal of clinical investigation, 2020-06, Vol.130 (6), p.3087-3097

2020

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Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell Biology

Frontiers in immunology, 2018-10, Vol.9, p.2486-2486

2018

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Engineering and Design of Chimeric Antigen Receptors

Molecular therapy. Methods & clinical development, 2019-03, Vol.12, p.145-156

2019

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Therapeutic intersections: Expanding benefits of CD19 CAR T cells from cancer to autoimmunity

Cell stem cell, 2024-04, Vol.31 (4), p.437-438

2024

Volltextzugriff (PDF)

Advances in cancer immunotherapies

Cell, 2023-04, Vol.186 (8), p.1814-1814.e1

2023

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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

Immunity (Cambridge, Mass.), 2016-06, Vol.44 (6), p.1444-1454

2016

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ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells

Blood, 2014-08, Vol.124 (7), p.1070-1080

2014

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Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Immunity (Cambridge, Mass.), 2016-02, Vol.44 (2), p.380-390

2016

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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies

Cell, 2020-10, Vol.183 (1), p.126-142.e17

2020

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Driving cars to the clinic for solid tumors

Gene therapy, 2018-06, Vol.25 (3), p.165-175

2018

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Sweet Immune Checkpoint Targets to Enhance T Cell Therapy

The Journal of immunology (1950), 2022-01, Vol.208 (2), p.278-285

2022

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Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

Cancer immunology research, 2017-12, Vol.5 (12), p.1152-1161

2017

Volltextzugriff (PDF)

Glycan-directed CAR-T cells

Glycobiology (Oxford), 2018-09, Vol.28 (9), p.656-669

2018

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CAR T-Cell Therapies in Glioblastoma: A First Look

Clinical cancer research, 2018-02, Vol.24 (3), p.535-540

2018

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Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager

Cancer immunology research, 2018-05, Vol.6 (5), p.605-616

2018

Volltextzugriff (PDF)

Distinguishing Truncated and Normal MUC1 Glycoform Targeting from Tn-MUC1-Specific CAR T Cells: Specificity Is the Key to Safety

Immunity (Cambridge, Mass.), 2016-11, Vol.45 (5), p.947-948

2016

Volltextzugriff (PDF)

Chimeric Antigen Receptor T-Cell Therapy: Current Perspective on T Cell-Intrinsic, T Cell-Extrinsic, and Therapeutic Limitations

The cancer journal (Sudbury, Mass.), 2023-01, Vol.29 (1), p.28

2023

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Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma

Science translational medicine, 2015-02, Vol.7 (275), p.275ra22

2015

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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety

Cancer cell, 2022-12, Vol.40 (12), p.1470-1487.e7

2022

Volltextzugriff (PDF)

Combination Therapy for Solid Tumors: Taking a Classic CAR on New Adventures

Cancer cell, 2020-11, Vol.38 (5), p.621-623

2020

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Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

JCI insight, 2018-01, Vol.3 (1)

2018

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Reprogramming T cells to target glycans and overcome glycan‐mediated immunosuppression for cancer therapy

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Posey, Avery D.

2022

Volltextzugriff (PDF)

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Immunity (Cambridge, Mass.), 2016-03, Vol.44 (3), p.712-712

2016

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Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting

Nature communications, 2021-07, Vol.12 (1), p.4365-4365, Article 4365

2021

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The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance

Nature communications, 2022-07, Vol.13 (1), p.4121-17, Article 4121

2022

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Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell Biology

Engineering and Design of Chimeric Antigen Receptors

Therapeutic intersections: Expanding benefits of CD19 CAR T cells from cancer to autoimmunity

Advances in cancer immunotherapies

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies

Driving cars to the clinic for solid tumors

Sweet Immune Checkpoint Targets to Enhance T Cell Therapy

Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

Glycan-directed CAR-T cells

CAR T-Cell Therapies in Glioblastoma: A First Look

Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager

Distinguishing Truncated and Normal MUC1 Glycoform Targeting from Tn-MUC1-Specific CAR T Cells: Specificity Is the Key to Safety

Chimeric Antigen Receptor T-Cell Therapy: Current Perspective on T Cell-Intrinsic, T Cell-Extrinsic, and Therapeutic Limitations

Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma

Expression of inducible factors reprograms CAR-T cells for enhanced function and safety

Combination Therapy for Solid Tumors: Taking a Classic CAR on New Adventures

Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

Reprogramming T cells to target glycans and overcome glycan‐mediated immunosuppression for cancer therapy

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting

The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance

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