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Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

Cytokine & growth factor reviews, 2014-02, Vol.25 (1), p.1-19

2014

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Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Breast cancer research : BCR, 2018-06, Vol.20 (1), p.54-54, Article 54

2018

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Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Nature communications, 2014-09, Vol.5 (1), p.4715-4715, Article 4715

2014

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Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

Frontiers in immunology, 2022-05, Vol.13, p.892250

2022

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Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells

PLoS computational biology, 2017-02, Vol.13 (2), p.e1005332-e1005332

2017

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Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer

PLoS computational biology, 2015-11, Vol.11 (11), p.e1004612-e1004612

2015

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A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade

Scientific reports, 2019-08, Vol.9 (1), p.11286-17, Article 11286

2019

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Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

Frontiers in pharmacology, 2023-06, Vol.14, p.1163432

2023

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Microcirculation and hemorheology

Annual review of fluid mechanics, 2005-01, Vol.37 (1), p.43-69

2005

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Expression of VEGF receptors on endothelial cells in mouse skeletal muscle

PloS one, 2012-09, Vol.7 (9), p.e44791-e44791

2012

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A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology

PLoS computational biology, 2019-11, Vol.15 (11), p.e1007468-e1007468

2019

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Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

PLoS computational biology, 2022-07, Vol.18 (7), p.e1010254

2022

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Red blood cell aggregation and dissociation in shear flows simulated by lattice Boltzmann method

Journal of biomechanics, 2008-01, Vol.41 (1), p.47-55

2008

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Anti-angiogenic peptides for cancer therapeutics

Current pharmaceutical biotechnology, 2011-08, Vol.12 (8), p.1101-1116

2011

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Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

PloS one, 2013-06, Vol.8 (6), p.e67438-e67438

2013

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A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer

The AAPS journal, 2019-06, Vol.21 (5), p.79-79, Article 79

2019

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Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway

Frontiers in physiology, 2024-02, Vol.15, p.1351753-1351753

2024

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Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases

International journal of molecular sciences, 2019-01, Vol.20 (2), p.421

2019

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Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model

PLoS computational biology, 2017-01, Vol.13 (1), p.e1005272-e1005272

2017

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Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows

Microvascular research, 2009-05, Vol.77 (3), p.265-272

2009

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Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC

Clinical and translational science, 2024-06, Vol.17 (6), p.e13811-n/a

2024

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Lymphatic endothelial cells support tumor growth in breast cancer

Scientific reports, 2014-07, Vol.4 (1), p.5853-5853, Article 5853

2014

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Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence

Genome medicine, 2023-09, Vol.15 (1), p.72-14, Article 72

2023

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Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer

Frontiers in physiology, 2020-10, Vol.11, p.583333-583333

2020

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An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

BMC systems biology, 2017-07, Vol.11 (1), p.68, Article 68

2017

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Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells

Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer

A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

Microcirculation and hemorheology

Expression of VEGF receptors on endothelial cells in mouse skeletal muscle

A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

Red blood cell aggregation and dissociation in shear flows simulated by lattice Boltzmann method

Anti-angiogenic peptides for cancer therapeutics

Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer

Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway

Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases

Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model

Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows

Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC

Lymphatic endothelial cells support tumor growth in breast cancer

Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence

Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer

An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

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