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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

Nature (London), 2020-01, Vol.577 (7792), p.695-700

2020

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Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin

Structure (London), 2012-07, Vol.20 (7), p.1167-1176

2012

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Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

Cell stem cell, 2016-09, Vol.19 (3), p.406-414

2016

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A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Nature communications, 2021-01, Vol.12 (1), p.463-463, Article 463

2021

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Calmodulin limits pathogenic Na+ channel persistent current

The Journal of general physiology, 2017-02, Vol.149 (2), p.277-293

2017

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Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel

Cell reports (Cambridge), 2012-01, Vol.1 (1), p.43-55

2012

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An interaction between the III-IV linker and CTD in NaV1.5 confers regulation of inactivation by CaM and FHF

The Journal of general physiology, 2020-02, Vol.152 (2), p.1

2020

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Current view on regulation of voltage‐gated sodium channels by calcium and auxiliary proteins

Protein science, 2016-09, Vol.25 (9), p.1573-1584

2016

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FGF14 Regulates Presynaptic Ca2+ Channels and Synaptic Transmission

Cell reports (Cambridge), 2013-07, Vol.4 (1), p.66-75

2013

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Fibroblast Growth Factor Homologous Factors Modulate Cardiac Calcium Channels

Circulation research, 2013-08, Vol.113 (4), p.381-388

2013

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α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current

PloS one, 2016-03, Vol.11 (3), p.e0152355-e0152355

2016

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Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

Nature communications, 2024-10, Vol.15 (1), p.8980-14, Article 8980

2024

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Fibroblast Growth Factor Homologous Factor 13 Regulates Na+ Channels and Conduction Velocity in Murine Hearts

Circulation research, 2011-09, Vol.109 (7), p.775-782

2011

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Voltage-Gated Calcium Channels in Nonexcitable Tissues

Annual review of physiology, 2021-02, Vol.83 (1), p.183-203

2021

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CaMKII tethers to L-type Ca²⁺ channels, establishing a local and dedicated integrator of Ca²⁺ signals for facilitation

The Journal of cell biology, 2005-11, Vol.171 (3), p.537-547

2005

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FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons

eLife, 2014-09, Vol.3, p.e04193-e04193

2014

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A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

Cell metabolism, 2012-07, Vol.16 (1), p.33-43

2012

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STIM1–Ca2+signaling modulates automaticity of the mouse sinoatrial node

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (41), p.E5618-E5627

2015

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Calcium Channel Mutations in Cardiac Arrhythmia Syndromes

Current molecular pharmacology, 2015-01, Vol.8 (2), p.133-142

2015

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SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12528-12533

2015

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Increased Ca2+ influx through CaV1.2 drives aortic valve calcification

JCI insight, 2022-03, Vol.7 (5)

2022

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Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction

PLoS genetics, 2012-12, Vol.8 (12), p.e1003113-e1003113

2012

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A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis

PloS one, 2014, Vol.9 (9), p.e106982-e106982

2014

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Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

The Journal of clinical investigation, 2013-04, Vol.123 (4), p.1638-1646

2013

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Ion Channels in Health and Disease

Pitt, Geoffrey S

1, 2016

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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics

Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Calmodulin limits pathogenic Na+ channel persistent current

Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel

An interaction between the III-IV linker and CTD in NaV1.5 confers regulation of inactivation by CaM and FHF

Current view on regulation of voltage‐gated sodium channels by calcium and auxiliary proteins

FGF14 Regulates Presynaptic Ca2+ Channels and Synaptic Transmission

Fibroblast Growth Factor Homologous Factors Modulate Cardiac Calcium Channels

α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current

Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

Fibroblast Growth Factor Homologous Factor 13 Regulates Na+ Channels and Conduction Velocity in Murine Hearts

Voltage-Gated Calcium Channels in Nonexcitable Tissues

CaMKII tethers to L-type Ca²⁺ channels, establishing a local and dedicated integrator of Ca²⁺ signals for facilitation

FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

STIM1–Ca2+signaling modulates automaticity of the mouse sinoatrial node

Calcium Channel Mutations in Cardiac Arrhythmia Syndromes

SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia

Increased Ca2+ influx through CaV1.2 drives aortic valve calcification

Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

Ion Channels in Health and Disease

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