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Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model

Journal of Alzheimer's disease, 2017-01, Vol.56 (2), p.775-788

2017

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The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

Brain, behavior, and immunity, 2018-10, Vol.73, p.21-33

2018

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Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model

PloS one, 2012-03, Vol.7 (3), p.e32568

2012

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Antibody‐mediated inhibition of tissue‐type plasminogen activator binding to the low‐density lipoprotein receptor‐related protein 1 as a potential beneficial modulator for stroke therapy

Journal of cellular biochemistry, 2023-07, Vol.124 (7), p.1040-1049

2023

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Endocrine Regulation of Microvascular Receptor-Mediated Transcytosis and Its Therapeutic Opportunities: Insights by PCSK9-Mediated Regulation

Pharmaceutics, 2023-04, Vol.15 (4), p.1268

2023

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Brain endothelial LRP1 maintains blood–brain barrier integrity

Fluids and barriers of the CNS, 2021-06, Vol.18 (1), p.1-27, Article 27

2021

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Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation

Glia, 2016-08, Vol.64 (8), p.1363-1380

2016

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The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease

Acta neuropathologica, 2019-02, Vol.137 (2), p.239-257

2019

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Truncated mini LRP1 transports cargo from luminal to basolateral side across the blood brain barrier

Fluids and barriers of the CNS, 2024-09, Vol.21 (1), p.74-23, Article 74

2024

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Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

Biochemical journal, 2015-08, Vol.470 (1), p.91-103

2015

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The LepR-mediated leptin transport across brain barriers controls food reward

Molecular metabolism (Germany), 2018-02, Vol.8, p.13-22

2018

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Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress

Redox biology, 2023-11, Vol.67, p.102943-102943, Article 102943

2023

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The role of lipoprotein receptors on the physiological function of APP

Experimental brain research, 2012-04, Vol.217 (3-4), p.377-387

2012

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Presenilin is the molecular target of acidic γ-secretase modulators in living cells

PloS one, 2012, Vol.7 (1), p.e30484

2012

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Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments

Frontiers in molecular neuroscience, 2017-01, Vol.10, p.21-21

2017

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Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity?

International journal of molecular sciences, 2021-05, Vol.22 (9), p.4998

2021

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A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Nature (London), 2001-11, Vol.414 (6860), p.212-216

2001

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Mechanisms of C-Reactive Protein-Induced Blood-Brain Barrier Disruption

Stroke (1970), 2009-04, Vol.40 (4), p.1458-1466

2009

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FE65 Constitutes the Functional Link between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein

The Journal of neuroscience, 2004-04, Vol.24 (17), p.4259-4265

2004

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APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Cellular and molecular life sciences : CMLS, 2012-04, Vol.69 (8), p.1353-1375

2012

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Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing

Experimental cell research, 2013-08, Vol.319 (13), p.1956-1972

2013

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Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease

Pharmaceutical research, 2017-12, Vol.34 (12), p.2637-2651

2017

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Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier

The Journal of clinical investigation, 2016-01, Vol.126 (1), p.123

2016

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Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

The Journal of clinical investigation, 2016-01, Vol.126 (1), p.123-136

2016

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Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

Acta neuropathologica communications, 2017-06, Vol.5 (1), p.49-49, Article 49

2017

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Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model

Antibody‐mediated inhibition of tissue‐type plasminogen activator binding to the low‐density lipoprotein receptor‐related protein 1 as a potential beneficial modulator for stroke therapy

Endocrine Regulation of Microvascular Receptor-Mediated Transcytosis and Its Therapeutic Opportunities: Insights by PCSK9-Mediated Regulation

Brain endothelial LRP1 maintains blood–brain barrier integrity

Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation

The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease

Truncated mini LRP1 transports cargo from luminal to basolateral side across the blood brain barrier

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

The LepR-mediated leptin transport across brain barriers controls food reward

Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress

The role of lipoprotein receptors on the physiological function of APP

Presenilin is the molecular target of acidic γ-secretase modulators in living cells

Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments

Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity?

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Mechanisms of C-Reactive Protein-Induced Blood-Brain Barrier Disruption

FE65 Constitutes the Functional Link between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing

Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease

Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier

Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

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