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Cysteine cathepsins: Their biological and molecular significance in cancer stem cells

Seminars in cancer biology, 2018-12, Vol.53, p.168-177

2018

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Lysosomal peptidases in innate immune cells: implications for cancer immunity

Cancer Immunology, Immunotherapy, 2020-02, Vol.69 (2), p.275-283

2020

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ROLE OF GAMMA-ENOLASE IN NEURONAL SPECIFIC SUBTYPE DIFFERENTIATION: THE IMPORTANCE OF ITS REGULATION BY CATHEPSIN X

IBRO neuroscience reports, 2023-10, Vol.15, p.S124-S124

2023

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Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.8167-8179

2014

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Cysteine Cathepsins in Tumor-Associated Immune Cells

Frontiers in immunology, 2019-08, Vol.10, p.2037-2037

2019

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Cysteine Cathepsins in Neurological Disorders

Molecular neurobiology, 2014-04, Vol.49 (2), p.1017-1030

2014

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The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.119-139

2018

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γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells

Cell communication and signaling, 2021-12, Vol.19 (1), p.118-18, Article 118

2021

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Cell models for Alzheimer’s and Parkinson’s disease: At the interface of biology and drug discovery

Biomedicine & pharmacotherapy, 2022-05, Vol.149, p.112924-112924, Article 112924

2022

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The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors

PLoS pathogens, 2020-11, Vol.16 (11), p.e1009013-e1009013

2020

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Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker

Cell & bioscience, 2024-05, Vol.14 (1), p.61-61, Article 61

2024

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Cathepsin X Activity Does Not Affect NK-Target Cell Synapse but Is Rather Distributed to Cytotoxic Granules

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13495

2021

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Stereoselective Activity of 1‑Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.1361-1387

2020

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Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation

Neuropharmacology, 2017-03, Vol.114, p.88-100

2017

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New Insights into the Role of Cysteine Cathepsins in Neuroinflammation

Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (12), p.1796

2021

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Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Scientific reports, 2016-12, Vol.6 (1), p.39495-39495, Article 39495

2016

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Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity

European journal of medicinal chemistry, 2021-01, Vol.209, p.112911-112911, Article 112911

2021

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Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease

Chemical communications (Cambridge, England), 2019-03, Vol.55 (26), p.3765-3768

2019

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Intracellular signaling by cathepsin X: Molecular mechanisms and diagnostic and therapeutic opportunities in cancer

Seminars in cancer biology, 2015-04, Vol.31, p.76-83

2015

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Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation

Molecular neurobiology, 2022-04, Vol.59 (4), p.2258-2276

2022

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Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells

Cancer Immunology, Immunotherapy, 2020-09, Vol.69 (9), p.1869-1880

2020

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Lysosomal cysteine peptidases – Molecules signaling tumor cell death and survival

Seminars in cancer biology, 2015-12, Vol.35, p.168-179

2015

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Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

European journal of medicinal chemistry, 2018-08, Vol.156, p.598-617

2018

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Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration

FEBS open bio, 2022-04, Vol.12 (4), p.708-738

2022

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Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

Frontiers in molecular neuroscience, 2020-11, Vol.13, p.575453-575453

2020

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Cysteine cathepsins: Their biological and molecular significance in cancer stem cells

Lysosomal peptidases in innate immune cells: implications for cancer immunity

ROLE OF GAMMA-ENOLASE IN NEURONAL SPECIFIC SUBTYPE DIFFERENTIATION: THE IMPORTANCE OF ITS REGULATION BY CATHEPSIN X

Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

Cysteine Cathepsins in Tumor-Associated Immune Cells

Cysteine Cathepsins in Neurological Disorders

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells

Cell models for Alzheimer’s and Parkinson’s disease: At the interface of biology and drug discovery

The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors

Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker

Cathepsin X Activity Does Not Affect NK-Target Cell Synapse but Is Rather Distributed to Cytotoxic Granules

Stereoselective Activity of 1‑Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation

New Insights into the Role of Cysteine Cathepsins in Neuroinflammation

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity

Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease

Intracellular signaling by cathepsin X: Molecular mechanisms and diagnostic and therapeutic opportunities in cancer

Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation

Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells

Lysosomal cysteine peptidases – Molecules signaling tumor cell death and survival

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

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