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Isocombretastatins A versus Combretastatins A: The Forgotten isoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4538-4542

2009

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p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles

Tetrahedron, 2010-05, Vol.66 (21), p.3775-3787

2010

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Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency

European journal of medicinal chemistry, 2020-08, Vol.199 (31), p.112355, Article 112355

2020

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New Novobiocin Analogues as Antiproliferative Agents in Breast Cancer Cells and Potential Inhibitors of Heat Shock Protein 90

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.6189-6200

2007

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p-Toluenesulfonic acid-mediated cyclization of o-(1-alkynyl)anisoles or thioanisoles: synthesis of 2-arylsubstituted benzofurans and benzothiophenes

Tetrahedron letters, 2009-07, Vol.50 (26), p.3588-3592

2009

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Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors

Organic & biomolecular chemistry, 2013-01, Vol.11 (3), p.430-442

2013

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Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents

ChemMedChem, 2009-11, Vol.4 (11), p.1912-1924

2009

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A Convenient Metal-Free Synthesis of (E)-3-Styrylisocoumarins through Annulation of (E)-1,4-Diarylenynes

Synthesis (Stuttgart), 2016-10, Vol.48 (19), p.3382-3392

2016

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Discovery and hit to lead optimization of novel combretastatin A-4 analogues: dependence of C-linker length and hybridization

Anti-cancer agents in medicinal chemistry, 2013-12, Vol.13 (10), p.1614-1635

2013

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Palladium-Catalyzed Cross-Coupling of 1-Aminoazoles with Aryl Chlorides: Application to the Synthesis of Unsymmetrical N,N′-Diaryl-1-aminoindoles

Advanced synthesis & catalysis, 2012-10, Vol.354 (14-15), p.2829-2839

2012

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Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives

European journal of medicinal chemistry, 2012-06, Vol.52, p.44-50

2012

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Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery

ChemMedChem, 2011-05, Vol.6 (5), p.804-815

2011

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Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells

Cancer letters, 2009-02, Vol.274 (1), p.88-94

2009

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Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (7), p.2495-2498

2008

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Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23

Biochemical and biophysical research communications, 2009-02, Vol.379 (2), p.514-518

2009

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Pd-Catalyzed Reaction of Sterically Hindered Hydrazones with Aryl Halides: Synthesis of Tetra-Substituted Olefins Related to iso-Combretastatin A4

Organic letters, 2010-09, Vol.12 (18), p.4042-4045

2010

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Assessing the chemical diversity of an hsp90 database

European journal of medicinal chemistry, 2010-05, Vol.45 (5), p.2000-2009

2010

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Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells

Human molecular genetics, 2012-11, Vol.21 (21), p.4615-4627

2012

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A General Copper Powder-Catalyzed Ullmann-Type Reaction of 3-Halo-4(1H)-quinolones With Various Nitrogen-Containing Nucleophiles

Journal of organic chemistry, 2011-06, Vol.76 (12), p.4995-5005

2011

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Ortho Substituents Direct Regioselective Addition of Tributyltin Hydride to Unsymmetrical Diaryl (or Heteroaryl) Alkynes: An Efficient Route to Stannylated Stilbene Derivatives

Angewandte Chemie International Edition, 2002-05, Vol.41 (9), p.1578-1580

2002

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Synthetic 2-methoxyestradiol derivatives: structure-activity relationships

Current medicinal chemistry, 2012-08, Vol.19 (24), p.4142-4156

2012

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Cs2CO3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

Tetrahedron letters, 2012-06, Vol.53 (23), p.2860-2863

2012

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An efficient coupling of N-tosylhydrazones with 2-halopyridines: synthesis of 2-α-styrylpyridines endowed with antitumor activity

Organic & biomolecular chemistry, 2013-06, Vol.11 (22), p.3664-3673

2013

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Synthesis and preliminary biological evaluation of new antiproliferative aromatic analogues of 1α,25-dihydroxyvitamin D3

European journal of medicinal chemistry, 2014-10, Vol.86, p.381-393

2014

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A convenient and expeditious synthesis of 3-(N-substituted) aminocoumarins via palladium-catalyzed Buchwald–Hartwig coupling reaction

Tetrahedron letters, 2007-09, Vol.48 (39), p.6928-6932

2007

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Isocombretastatins A versus Combretastatins A: The Forgotten isoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency

New Novobiocin Analogues as Antiproliferative Agents in Breast Cancer Cells and Potential Inhibitors of Heat Shock Protein 90

p-Toluenesulfonic acid-mediated cyclization of o-(1-alkynyl)anisoles or thioanisoles: synthesis of 2-arylsubstituted benzofurans and benzothiophenes

Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors

Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents

A Convenient Metal-Free Synthesis of (E)-3-Styrylisocoumarins through Annulation of (E)-1,4-Diarylenynes

Discovery and hit to lead optimization of novel combretastatin A-4 analogues: dependence of C-linker length and hybridization

Palladium-Catalyzed Cross-Coupling of 1-Aminoazoles with Aryl Chlorides: Application to the Synthesis of Unsymmetrical N,N′-Diaryl-1-aminoindoles

Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives

Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery

Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells

Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)

Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23

Pd-Catalyzed Reaction of Sterically Hindered Hydrazones with Aryl Halides: Synthesis of Tetra-Substituted Olefins Related to iso-Combretastatin A4

Assessing the chemical diversity of an hsp90 database

Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells

A General Copper Powder-Catalyzed Ullmann-Type Reaction of 3-Halo-4(1H)-quinolones With Various Nitrogen-Containing Nucleophiles

Ortho Substituents Direct Regioselective Addition of Tributyltin Hydride to Unsymmetrical Diaryl (or Heteroaryl) Alkynes: An Efficient Route to Stannylated Stilbene Derivatives

Synthetic 2-methoxyestradiol derivatives: structure-activity relationships

Cs2CO3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

An efficient coupling of N-tosylhydrazones with 2-halopyridines: synthesis of 2-α-styrylpyridines endowed with antitumor activity

Synthesis and preliminary biological evaluation of new antiproliferative aromatic analogues of 1α,25-dihydroxyvitamin D3

A convenient and expeditious synthesis of 3-(N-substituted) aminocoumarins via palladium-catalyzed Buchwald–Hartwig coupling reaction

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