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An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Journal of Virology, 2005-10, Vol.79 (20), p.13139-13149

2005

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structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (13), p.4425-4430

2004

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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.2789-2801

2020

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VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus Phylogeny and Susceptibility to Antiviral Capsid-Binding Compounds

Journal of Virology, 2004-04, Vol.78 (7), p.3663-3674

2004

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VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

2020

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Potent Antiviral Synergy between Monoclonal Antibody and Small-Molecule CCR5 Inhibitors of Human Immunodeficiency Virus Type 1

Antimicrobial Agents and Chemotherapy, 2006-10, Vol.50 (10), p.3289-3296

2006

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Activity of Pleconaril against Enteroviruses

Antimicrobial Agents and Chemotherapy, 1999-09, Vol.43 (9), p.2109-2115

1999

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Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073

Antimicrobial Agents and Chemotherapy, 2012-11, Vol.56 (11), p.5568-5574

2012

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In Vitro Antiviral Activity of V-073 against Polioviruses

Antimicrobial Agents and Chemotherapy, 2009-10, Vol.53 (10), p.4501-4503

2009

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In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS) Program

Antimicrobial agents and chemotherapy, 2023-01, Vol.67 (1), p.e0128122-e0128122

2023

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Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses

Antimicrobial Agents and Chemotherapy, 2005-11, Vol.49 (11), p.4492-4499

2005

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Ceftibuten-Ledaborbactam Activity against Multidrug-Resistant and Extended-Spectrum-β-Lactamase-Positive Clinical Isolates of Enterobacterales from a 2018-2020 Global Surveillance Collection

Antimicrobial agents and chemotherapy, 2022-11, Vol.66 (11), p.e0093422-e0093422

2022

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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.10155-10166

2021

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Microbiological Characterization of VNRX-5236, a Broad-Spectrum β-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agent against Strains of Enterobacterales Expressing Extended-Spectrum β-Lactamases and Serine Carbapenemases

Antimicrobial agents and chemotherapy, 2021-07, Vol.65 (8), p.e0055221-e0055221

2021

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Biographical Feature: Marc S. Collett (23 May 1951-11 June 2022): the Battle against Viral Disease Has Lost a Valiant Warrior, and the World Has Lost a Splendid Human Being

Journal of virology, 2023-01, Vol.97 (1), p.e0164322-e0164322

2023

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Structural and Virological Studies of the Stages of Virus Replication That Are Affected by Antirhinovirus Compounds

Journal of Virology, 2004-10, Vol.78 (20), p.11061-11069

2004

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Mechanism of Action of a Pestivirus Antiviral Compound

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.7981-7986

2000

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Attenuated Virulence of Pleconaril-Resistant Coxsackievirus B3 Variants

The Journal of infectious diseases, 1999-06, Vol.179 (6), p.1538-1541

1999

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Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials

Clinical infectious diseases, 2003-06, Vol.36 (12), p.1523-1532

2003

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The structure of coxsackievirus B3 at 3.5 å resolution

Structure (London), 1995-07, Vol.3 (7), p.653-667

1995

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Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

Journal of Virology, 2004-09, Vol.78 (18), p.10202-10205

2004

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Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses

Antiviral research, 2006-02, Vol.69 (2), p.86-97

2006

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N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1442-1444

2007

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Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril

Antiviral research, 2005-12, Vol.68 (3), p.135-138

2005

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Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Journal of medicinal chemistry, 1995-04, Vol.38 (8), p.1355-1371

1995

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An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus Phylogeny and Susceptibility to Antiviral Capsid-Binding Compounds

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

Potent Antiviral Synergy between Monoclonal Antibody and Small-Molecule CCR5 Inhibitors of Human Immunodeficiency Virus Type 1

Activity of Pleconaril against Enteroviruses

Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073

In Vitro Antiviral Activity of V-073 against Polioviruses

In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS) Program

Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses

Ceftibuten-Ledaborbactam Activity against Multidrug-Resistant and Extended-Spectrum-β-Lactamase-Positive Clinical Isolates of Enterobacterales from a 2018-2020 Global Surveillance Collection

Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes

Microbiological Characterization of VNRX-5236, a Broad-Spectrum β-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agent against Strains of Enterobacterales Expressing Extended-Spectrum β-Lactamases and Serine Carbapenemases

Biographical Feature: Marc S. Collett (23 May 1951-11 June 2022): the Battle against Viral Disease Has Lost a Valiant Warrior, and the World Has Lost a Splendid Human Being

Structural and Virological Studies of the Stages of Virus Replication That Are Affected by Antirhinovirus Compounds

Mechanism of Action of a Pestivirus Antiviral Compound

Attenuated Virulence of Pleconaril-Resistant Coxsackievirus B3 Variants

Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials

The structure of coxsackievirus B3 at 3.5 å resolution

Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses

N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors

Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

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