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Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

Nature medicine, 2016-01, Vol.22 (1), p.105-113

2016

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Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms

Frontiers in oncology, 2023-10, Vol.13, p.1223199-1223199

2023

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Asymmetric cell division of stem and progenitor cells during homeostasis and cancer

Cellular and molecular life sciences : CMLS, 2014-02, Vol.71 (4), p.575-597

2014

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Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

Nature medicine, 2014-12, Vol.20 (12), p.1394-1396

2014

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BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas

Clinical cancer research, 2016-11, Vol.22 (21), p.5312-5321

2016

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

BMC medicine, 2008-06, Vol.6 (1), p.14-14, Article 14

2008

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A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium

International journal of cancer, 2019-10, Vol.145 (7), p.1889-1901

2019

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EXPANDS: expanding ploidy and allele frequency on nested subpopulations

Bioinformatics, 2014-01, Vol.30 (1), p.50-60

2014

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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Cell reports (Cambridge), 2022-02, Vol.38 (7), p.110375-110375, Article 110375

2022

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Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Nature communications, 2018-08, Vol.9 (1), p.2862-15, Article 2862

2018

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Regulation of Asymmetric Cell Division in Mammalian Neural Stem and Cancer Precursor Cells

Asymmetric Cell Division in Development, Differentiation and Cancer, 2017-01, Vol.61, p.375-399

2017

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Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (24), p.5355-5366

2015

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Numerical chromosomal instability mediates susceptibility to radiation treatment

Nature communications, 2015-01, Vol.6 (1), p.5990-5990, Article 5990

2015

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Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM

Neuro-oncology (Charlottesville, Va.), 2008-06, Vol.10 (3), p.254-264

2008

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CDC42BPA::BRAF represents a novel fusion in desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma

Neuro-oncology advances, 2024-01, Vol.6 (1), p.vdae050-vdae050

2024

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Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

Oncotarget, 2016-11, Vol.7 (46), p.75839-75853

2016

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BIOL-06. UNDERSTANDING OLIGODENDROCYTE PROGENITOR CELL CONTRIBUTION TO GLIOMAGENESIS USING A NOVEL PHARMACOGENETIC ABLATION TOOL

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i6-i7

2023

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STEM-01. INVESTIGATING ASPM FUNCTION IN REGULATION OF CELL DIVISION MODE OF OLIGODENDROCYTE PROGENITOR CELLS

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi226-vi226

2017

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STEM-05. THE CONSERVED TUMOR SUPPRESSOR LGL1 REGULATES ADULT OLIGODENDROCYTE PROGENITOR CELL DIVISION MODE AND PREVENTS PREMALIGNANT PHENOTYPES

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi227-vi227

2017

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DDDR-19. FIRST-IN-CLASS CANCER THERAPEUTICS TARGETING THE DNA DAMAGE RESPONSE

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v109-v109

2023

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MODL-45. UNDERSTANDING OLIGODENDROCYTE PROGENITOR CELL CONTRIBUTION TO GLIOMAGENESIS USING A NOVEL PHARMACOGENETIC ABLATION TOOL

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v308-v309

2023

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Abstract 916: Asymmetric cell division regulator prevents hyperproliferation in glioma cell-of-origin

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.916-916

2017

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IMG-31. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Suppl 4), p.0-0

2024

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LGG-05. GENERATION OF NOVEL MOUSE MODELS FOR BRAF V600E MUTANT GLIOMAGENESIS TO GAIN MECHANISTIC INSIGHTS INTO TUMOR FORMATION AND PROGRESSION

Neuro-oncology (Charlottesville, Va.), 2021-06, Vol.23 (Supplement_1), p.i32-i32

2021

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Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (22), p.8710-8715

2012

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Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms

Asymmetric cell division of stem and progenitor cells during homeostasis and cancer

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium

EXPANDS: expanding ploidy and allele frequency on nested subpopulations

LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Regulation of Asymmetric Cell Division in Mammalian Neural Stem and Cancer Precursor Cells

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

Numerical chromosomal instability mediates susceptibility to radiation treatment

Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM

CDC42BPA::BRAF represents a novel fusion in desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

BIOL-06. UNDERSTANDING OLIGODENDROCYTE PROGENITOR CELL CONTRIBUTION TO GLIOMAGENESIS USING A NOVEL PHARMACOGENETIC ABLATION TOOL

STEM-01. INVESTIGATING ASPM FUNCTION IN REGULATION OF CELL DIVISION MODE OF OLIGODENDROCYTE PROGENITOR CELLS

STEM-05. THE CONSERVED TUMOR SUPPRESSOR LGL1 REGULATES ADULT OLIGODENDROCYTE PROGENITOR CELL DIVISION MODE AND PREVENTS PREMALIGNANT PHENOTYPES

DDDR-19. FIRST-IN-CLASS CANCER THERAPEUTICS TARGETING THE DNA DAMAGE RESPONSE

MODL-45. UNDERSTANDING OLIGODENDROCYTE PROGENITOR CELL CONTRIBUTION TO GLIOMAGENESIS USING A NOVEL PHARMACOGENETIC ABLATION TOOL

Abstract 916: Asymmetric cell division regulator prevents hyperproliferation in glioma cell-of-origin

IMG-31. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS

LGG-05. GENERATION OF NOVEL MOUSE MODELS FOR BRAF V600E MUTANT GLIOMAGENESIS TO GAIN MECHANISTIC INSIGHTS INTO TUMOR FORMATION AND PROGRESSION

Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

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