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CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8391-8396

2015

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TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Journal of leukocyte biology, 2009-06, Vol.85 (6), p.966-977

2009

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Microbiota-Derived Metabolites, Indole-3-aldehyde and Indole-3-acetic Acid, Differentially Modulate Innate Cytokines and Stromal Remodeling Processes Associated with Autoimmune Arthritis

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2017

2021

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cAMP levels regulate macrophage alternative activation marker expression

Innate immunity (London, England), 2021-02, Vol.27 (2), p.133-142

2021

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5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

The Journal of biological chemistry, 2012-11, Vol.287 (47), p.39776-39788

2012

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Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)

Cytokine (Philadelphia, Pa.), 2015-08, Vol.74 (2), p.171-174

2015

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Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists

The Journal of immunology (1950), 2012-07, Vol.189 (1), p.50-60

2012

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Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

The Journal of immunology (1950), 2015-09, Vol.195 (5), p.2461-2471

2015

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Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages

PLoS neglected tropical diseases, 2015-01, Vol.9 (1), p.e3394-e3394

2015

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Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection

mBio, 2019-05, Vol.10 (3)

2019

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M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

mBio, 2023-10, Vol.14 (5), p.e0120823-e0120823

2023

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Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages

The Journal of immunology (1950), 2013-05, Vol.190 (9), p.4763-4772

2013

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The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

Infection and immunity, 2016-06, Vol.84 (6), p.1796-1805

2016

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The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005803-e1005803

2016

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Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003479-e1003479

2013

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AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

The Journal of biological chemistry, 2017-01, Vol.292 (1), p.292-304

2017

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A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses

The Journal of experimental medicine, 2021-02, Vol.218 (2)

2021

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Defects in Translational Regulation Mediated by the α Subunit of Eukaryotic Initiation Factor 2 Inhibit Antiviral Activity and Facilitate the Malignant Transformation of Human Fibroblasts

Molecular and Cellular Biology, 2004-03, Vol.24 (5), p.2025-2040

2004

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A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination

mBio, 2010-10, Vol.1 (5), p.e00239-e00239

2010

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Inflammation: Species-specific TLR signalling -- insight into human disease

Nature reviews. Rheumatology, 2016-04, Vol.12 (4), p.198

2016

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Epigenetic Mechanisms Governing Innate Inflammatory Responses

Journal of interferon & cytokine research, 2016-07, Vol.36 (7), p.454

2016

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Dissociation of TRIF bias and adjuvanticity

Vaccine, 2020-06, Vol.38 (27), p.4298-4308

2020

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Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice

The Journal of immunology (1950), 2013-01, Vol.190 (1), p.307-316

2013

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Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity

Infection and immunity, 2018-12, Vol.86 (12)

2018

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Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain

Innate immunity (London, England), 2016-07, Vol.22 (5), p.363-372

2016

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CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Microbiota-Derived Metabolites, Indole-3-aldehyde and Indole-3-acetic Acid, Differentially Modulate Innate Cytokines and Stromal Remodeling Processes Associated with Autoimmune Arthritis

cAMP levels regulate macrophage alternative activation marker expression

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)

Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists

Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages

Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection

M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production

AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses

Defects in Translational Regulation Mediated by the α Subunit of Eukaryotic Initiation Factor 2 Inhibit Antiviral Activity and Facilitate the Malignant Transformation of Human Fibroblasts

A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination

Inflammation: Species-specific TLR signalling -- insight into human disease

Epigenetic Mechanisms Governing Innate Inflammatory Responses

Dissociation of TRIF bias and adjuvanticity

Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice

Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity

Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain

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