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CpG Oligodeoxynucleotides Protect Newborn Mice from a Lethal Challenge with the Neurotropic Tacaribe Arenavirus

Journal of Immunology, 2006-04, Vol.176 (8), p.4940-4949

2006

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Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals

mAbs, 2024, Vol.16 (1), p.2324801-2324801

2024

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Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins

Trends in biotechnology (Regular ed.), 2018-10, Vol.36 (10), p.1068-1084

2018

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Immunotherapy with CpG oligonucleotides and antibodies to TNF-alpha rescues neonatal mice from lethal arenavirus-induced meningoencephalitis

The Journal of immunology (1950), 2008-06, Vol.180 (12), p.8231-8240

2008

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2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3 - LBA: immunogenicity, biomarkers and PK assays)

Bioanalysis, 2017-12, Vol.9 (24), p.1967-1996

2017

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CD4 and CD8 T cells mediate distinct lethal meningoencephalitis in mice challenged with Tacaribe arenavirus

Cellular & molecular immunology, 2017-01, Vol.14 (1), p.90-106

2017

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2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 – Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62)

Bioanalysis, 2019-12, Vol.11 (24), p.2207-2244

2019

Volltextzugriff (PDF)

Neutralizing Antibody Validation Testing and Reporting Harmonization

The AAPS journal, 2023-07, Vol.25 (4), p.69-69, Article 69

2023

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2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays)

Bioanalysis, 2018-12, Vol.10 (24), p.1973-2001

2018

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CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

Infection and Immunity, 2005-09, Vol.73 (9), p.6154-6156

2005

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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity)

Bioanalysis, 2016-12, Vol.8 (23), p.2475-2496

2016

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2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity)

Bioanalysis, 2018-12, Vol.10 (23), p.1897-1917

2018

Volltextzugriff (PDF)

High-throughput real-time PCR for early detection and quantitation of arenavirus Tacaribe

Journal of virological methods, 2009-08, Vol.159 (2), p.239-243

2009

Volltextzugriff (PDF)

2017 White Paper: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs)

Bioanalysis, 2017-12, Vol.9 (23), p.1895-1912

2017

Volltextzugriff (PDF)

Feedback from the European Bioanalysis Forum: focus workshop on current analysis of immunogenicity: best practices and regulatory hurdles

Bioanalysis, 2018-02, Vol.10 (4), p.197-204

2018

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Cross-Reactive Antigen Is Required to Prevent Erosion of Established T Cell Memory and Tumor Immunity: A Heterologous Bacterial Model of Attrition

The Journal of immunology (1950), 2002-08, Vol.169 (3), p.1197-1206

2002

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Increased CD8+ T Cell Memory to Concurrent Infection at the Expense of Increased Erosion of Pre-existing Memory: The Paradoxical Role of IL-15

The Journal of immunology (1950), 2003-11, Vol.171 (10), p.5454-5460

2003

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Design and Development of Thermolytic DNA Oligonucleotide Prodrugs

Annals of the New York Academy of Sciences, 2005-11, Vol.1058 (1), p.26-38

2005

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Severe Schistosomiasis in the Absence of Interleukin-4 (IL-4) Is IL-12 Independent

Infection and Immunity, 2001-01, Vol.69 (1), p.589-592

2001

Volltextzugriff (PDF)

Mycobacterium bovis BCG-Infected Mice Are More Susceptible to Staphylococcal Enterotoxin B-Mediated Toxic Shock than Uninfected Mice despite Reduced In Vitro Splenocyte Responses to Superantigens

Infection and Immunity, 2002-08, Vol.70 (8), p.4148-4157

2002

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Profound effect of the absence of IL-4 on T cell responses during infection with Schistosoma mansoni

Journal of leukocyte biology, 2001-11, Vol.70 (5), p.737-744

2001

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GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune Encephalomyelitis

Journal of Immunology, 2007-01, Vol.178 (1), p.39-48

2007

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Strategies to Determine Assay Format for the Assessment of Neutralizing Antibody Responses to Biotherapeutics

The AAPS journal, 2016-11, Vol.18 (6), p.1335-1350

2016

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CpG Oligodeoxynucleotides Protect Newborn Mice from a Lethal Challenge with the Neurotropic Tacaribe Arenavirus

Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals

Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins

Immunotherapy with CpG oligonucleotides and antibodies to TNF-alpha rescues neonatal mice from lethal arenavirus-induced meningoencephalitis

2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3 - LBA: immunogenicity, biomarkers and PK assays)

CD4 and CD8 T cells mediate distinct lethal meningoencephalitis in mice challenged with Tacaribe arenavirus

Anti-drug Antibody Validation Testing and Reporting Harmonization

Neutralizing Antibody Validation Testing and Reporting Harmonization

2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays)

CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity)

2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity)

High-throughput real-time PCR for early detection and quantitation of arenavirus Tacaribe

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 - Hybrid LBA/LCMS and input from regulatory agencies)

2017 White Paper: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs)

Feedback from the European Bioanalysis Forum: focus workshop on current analysis of immunogenicity: best practices and regulatory hurdles

Cross-Reactive Antigen Is Required to Prevent Erosion of Established T Cell Memory and Tumor Immunity: A Heterologous Bacterial Model of Attrition

Increased CD8+ T Cell Memory to Concurrent Infection at the Expense of Increased Erosion of Pre-existing Memory: The Paradoxical Role of IL-15

Design and Development of Thermolytic DNA Oligonucleotide Prodrugs

Severe Schistosomiasis in the Absence of Interleukin-4 (IL-4) Is IL-12 Independent

Mycobacterium bovis BCG-Infected Mice Are More Susceptible to Staphylococcal Enterotoxin B-Mediated Toxic Shock than Uninfected Mice despite Reduced In Vitro Splenocyte Responses to Superantigens

Profound effect of the absence of IL-4 on T cell responses during infection with Schistosoma mansoni

GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune Encephalomyelitis

Strategies to Determine Assay Format for the Assessment of Neutralizing Antibody Responses to Biotherapeutics

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