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Enriching metabolite fractions for assessment of AHR activation potential: a proof of concept study

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100882, Article 100882

2024

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Utility and limitations of dual cholate shunt assay in preclinical species

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S75-S75

2019

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Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity

Toxicological sciences, 2019-07, Vol.170 (1), p.180-198

2019

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A field‐validated species distribution model to support management of the critically endangered Poweshiek skipperling (Oarisma poweshiek) butterfly in Canada

Conservation science and practice, 2020-03, Vol.2 (3), p.n/a

2020

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P234 - Use of a bile salt export pump knockdown rat susceptibility model to interrogate mechanism of drug induced liver toxicity

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S93-S93

2020

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Image-guided Drainage of Tuboovarian Abscesses of Gastrointestinal or Genitourinary Origin: A Retrospective Analysis

Journal of vascular and interventional radiology, 2011-05, Vol.22 (5), p.678-686

2011

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Intramolecular cross-linking experiments on cytochrome c and ribonuclease A using an isotope multiplet method

Rapid communications in mass spectrometry, 2002-01, Vol.16 (3), p.149-159

2002

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Rapid and Definitive Identification of Cyclic Peptide Soft Spots by Isotope-Labeled Reductive Dimethylation and Mass Spectrometry Fragmentation

Analytical chemistry (Washington), 2024-05, Vol.96 (19), p.7756-7762

2024

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The application of cytokeratin-18 as a biomarker for drug-induced liver injury

Archives of toxicology, 2021-11, Vol.95 (11), p.3435-3448

2021

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Leveraging High-Resolution Ion Mobility-Mass Spectrometry for Cyclic Peptide Soft Spot Identification

Journal of the American Society for Mass Spectrometry, 2024-11, Vol.35 (11), p.2596-2607

2024

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Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities

Toxicological sciences, 2020-05, Vol.175 (1), p.98-112

2020

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AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats

Toxicological sciences, 2019-09, Vol.171 (1), p.46-55

2019

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Effects of LRRK2 Inhibitors in Nonhuman Primates

Toxicologic pathology, 2023-07, Vol.51 (5), p.232-245

2023

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Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury

Chemical research in toxicology, 2019-08, Vol.32 (8), p.1528-1544

2019

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Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14912-14927

2023

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Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice

Toxicology and applied pharmacology, 2020-11, Vol.406, p.115216, Article 115216

2020

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Habitat associations and distribution model for Fuscopannaria leucosticta in Nova Scotia, Canada

The Lichenologist (London), 2018-07, Vol.50 (4), p.487-497

2018

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Physiologically-based modeling of cholate disposition in beagle dog with and without treatment of the liver transporter inhibitor simeprevir

Computational toxicology, 2022-05, Vol.22, p.100224, Article 100224

2022

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Oxidative Modifications of Kynostatin-272, a Potent Human Immunodeficiency Virus Type 1 Protease Inhibitor: Potential Mechanism for Altered Activity in Monocytes/Macrophages

Antimicrobial Agents and Chemotherapy, 2002-02, Vol.46 (2), p.402-408

2002

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Inhibin B Response to Testicular Toxicants Hexachlorophene, Ethane Dimethane Sulfonate, Di-(n-butyl)-phthalate, Nitrofurazone, DL-Ethionine, 17-alpha Ethinylestradiol, 2,5-Hexanedione, or Carbendazim Following Short-Term Dosing in Male Rats: Special Issue on Inhibin B Biomarker Research

Birth defects research. A Clinical and molecular teratology, 2013, Vol.98 (1), p.41-53

2013

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Inhibin B Response to Testicular Toxicants Hexachlorophene, Ethane Dimethane Sulfonate, Di-(n-butyl)-phthalate, Nitrofurazone, DL-Ethionine, 17-alpha Ethinylestradiol, 2,5-Hexanedione, or Carbendazim Following Short-Term Dosing in Male Rats

Birth defects research. Part B. Developmental and reproductive toxicology, 2013-02, Vol.98 (1), p.41-53

2013

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Using natural products to elucidate a multidrug resistance pathway

Pearson, Kara Michelle

2000

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Patterns in reporting and participant inclusion related to race and ethnicity in autism intervention literature: Data from a large-scale systematic review of evidence-based practices

Autism : the international journal of research and practice, 2022-11, Vol.26 (8), p.2026-2040

2022

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Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

PLoS genetics, 2014-05, Vol.10 (5), p.e1004323-e1004323

2014

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Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

Disease models & mechanisms, 2015-03, Vol.8 (3), p.237-251

2015

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Enriching metabolite fractions for assessment of AHR activation potential: a proof of concept study

Utility and limitations of dual cholate shunt assay in preclinical species

Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity

A field‐validated species distribution model to support management of the critically endangered Poweshiek skipperling (Oarisma poweshiek) butterfly in Canada

P234 - Use of a bile salt export pump knockdown rat susceptibility model to interrogate mechanism of drug induced liver toxicity

Image-guided Drainage of Tuboovarian Abscesses of Gastrointestinal or Genitourinary Origin: A Retrospective Analysis

Intramolecular cross-linking experiments on cytochrome c and ribonuclease A using an isotope multiplet method

Rapid and Definitive Identification of Cyclic Peptide Soft Spots by Isotope-Labeled Reductive Dimethylation and Mass Spectrometry Fragmentation

The application of cytokeratin-18 as a biomarker for drug-induced liver injury

Leveraging High-Resolution Ion Mobility-Mass Spectrometry for Cyclic Peptide Soft Spot Identification

Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities

AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats

Effects of LRRK2 Inhibitors in Nonhuman Primates

Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury

Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease

Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice

Habitat associations and distribution model for Fuscopannaria leucosticta in Nova Scotia, Canada

Physiologically-based modeling of cholate disposition in beagle dog with and without treatment of the liver transporter inhibitor simeprevir

Oxidative Modifications of Kynostatin-272, a Potent Human Immunodeficiency Virus Type 1 Protease Inhibitor: Potential Mechanism for Altered Activity in Monocytes/Macrophages

Inhibin B Response to Testicular Toxicants Hexachlorophene, Ethane Dimethane Sulfonate, Di-(n-butyl)-phthalate, Nitrofurazone, DL-Ethionine, 17-alpha Ethinylestradiol, 2,5-Hexanedione, or Carbendazim Following Short-Term Dosing in Male Rats: Special Issue on Inhibin B Biomarker Research

Inhibin B Response to Testicular Toxicants Hexachlorophene, Ethane Dimethane Sulfonate, Di-(n-butyl)-phthalate, Nitrofurazone, DL-Ethionine, 17-alpha Ethinylestradiol, 2,5-Hexanedione, or Carbendazim Following Short-Term Dosing in Male Rats

Using natural products to elucidate a multidrug resistance pathway

Patterns in reporting and participant inclusion related to race and ethnicity in autism intervention literature: Data from a large-scale systematic review of evidence-based practices

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

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