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Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

The European respiratory journal, 2015-05, Vol.45 (5), p.1434-1445

2015

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Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Nature (London), 2011-01, Vol.469 (7329), p.175-180

2011

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Covalent inhibitor reactivity prediction by the electrophilicity index—in and out of scope

Journal of computer-aided molecular design, 2021-04, Vol.35 (4), p.531-539

2021

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Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1

Nature communications, 2023-09, Vol.14 (1), p.5696-12, Article 5696

2023

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Fast native-SAD phasing for routine macromolecular structure determination

Nature methods, 2015-02, Vol.12 (2), p.131-133

2015

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Molecular Recognition of the Protein Phosphatase 1 Glycogen Targeting Subunit by Glycogen Phosphorylase

The Journal of biological chemistry, 2008-04, Vol.283 (14), p.8913-8918

2008

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Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme

The EMBO journal, 2005-10, Vol.24 (20), p.3670-3680

2005

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The cryo-electron microscopy structure of huntingtin

Nature (London), 2018-03, Vol.555 (7694), p.117-120

2018

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A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides

Journal of chemical information and modeling, 2019-08, Vol.59 (8), p.3565-3571

2019

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BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity

Journal of chemical information and modeling, 2020-06, Vol.60 (6), p.2915-2923

2020

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Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability

Bioorganic & medicinal chemistry letters, 2024-11, Vol.112, p.129930, Article 129930

2024

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Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design

Acta crystallographica. Section D, Biological crystallography., 2023-10, Vol.79 (10), p.871-880

2023

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C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins

Naunyn-Schmiedeberg's archives of pharmacology, 2007-02, Vol.374 (5-6), p.347-360

2007

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Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists

Structure (London), 2019-03, Vol.27 (3), p.427-438.e5

2019

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Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex

Structure (London), 2021-08, Vol.29 (8), p.804-809.e5

2021

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A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems

Protein expression and purification, 2012-04, Vol.82 (2), p.308-316

2012

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Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism

ACS chemical biology, 2022-04, Vol.17 (4), p.816-821

2022

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Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

Crystal growth & design, 2014-04, Vol.14 (4), p.2034-2047

2014

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Crystal Structure of Glucokinase Regulatory Protein

Biochemistry (Easton), 2013-05, Vol.52 (20), p.3523-3531

2013

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Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib

ACS chemical biology, 2016-06, Vol.11 (6), p.1595-1602

2016

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The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling

ACS medicinal chemistry letters, 2011-06, Vol.2 (6), p.414-418

2011

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Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase

Structure (London), 2001-10, Vol.9 (10), p.955-965

2001

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Erratum: Corrigendum: Fast native-SAD phasing for routine macromolecular structure determination

Nature methods, 2015-06, Vol.12 (7), p.692-692

2015

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Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase: Insight into Domain Movements upon Kinase Activation

Structure (London), 2001-10, Vol.9 (10), p.955-965

2001

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Structure of a nanobody--stabilized active state of the [β.sub.2] adrenoceptor

Nature (London), 2011-01, Vol.469 (7329), p.175

2011

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Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Covalent inhibitor reactivity prediction by the electrophilicity index—in and out of scope

Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1

Fast native-SAD phasing for routine macromolecular structure determination

Molecular Recognition of the Protein Phosphatase 1 Glycogen Targeting Subunit by Glycogen Phosphorylase

Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme

The cryo-electron microscopy structure of huntingtin

A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides

BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity

Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability

Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design

C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins

Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists

Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex

A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems

Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

Crystal Structure of Glucokinase Regulatory Protein

Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib

The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling

Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase

Erratum: Corrigendum: Fast native-SAD phasing for routine macromolecular structure determination

Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase: Insight into Domain Movements upon Kinase Activation

Structure of a nanobody--stabilized active state of the [β.sub.2] adrenoceptor

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