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Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
Nature communications, 2018-01, Vol.9 (1), p.446-14, Article 446
2018
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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
Cancer cell, 2013-08, Vol.24 (2), p.213-228
2013
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The pentose phosphate pathway and cancer
Trends in biochemical sciences (Amsterdam. Regular ed.), 2014-08, Vol.39 (8), p.347-354
2014
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Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm
Clinical and translational gastroenterology, 2017-04, Vol.8 (4), p.e86-e86
2017
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Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
Nature cell biology, 2018-07, Vol.20 (7), p.811
2018
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A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis
Nature communications, 2022-02, Vol.13 (1), p.899-20, Article 899
2022
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Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation
eLife, 2018-04, Vol.7
2018
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Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms
eLife, 2023-01, Vol.12
2023
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Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
Nature communications, 2018-06, Vol.9 (1), p.2539-1, Article 2539
2018
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Systemic Akt1 Deletion after Tumor Onset in p53−/− Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration
Cell reports (Cambridge), 2015-07, Vol.12 (4), p.610-621
2015
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AMPK-Mediated Lysosome Biogenesis in Lung Cancer Growth
Cell metabolism, 2019-02, Vol.29 (2), p.238-240
2019
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A Cell Size Theory of Aging
Developmental cell, 2018-06, Vol.45 (6), p.665-666
2018
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EGFR Pathway Links Amino Acid Levels and Induction of Macropinocytosis
Developmental cell, 2019-08, Vol.50 (3), p.261-263
2019
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TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma
Cancer discovery, 2019-08, Vol.9 (8), p.1064-1079
2019
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Hexokinase 2 as oncotarget
Oncotarget, 2013-11, Vol.4 (11), p.1862-1863
2013
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DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer
Cancer research (Chicago, Ill.), 2013-06, Vol.73 (12), p.3771-3782
2013
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BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis
World journal of hepatology, 2021-03, Vol.13 (3), p.343-361
2021
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mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhibition
Molecular and Cellular Biology, 2009-09, Vol.29 (18), p.5136-5147
2009
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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
Cancer cell, 2013-09, Vol.24 (3), p.399-399
2013
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Baculovirus repeat-containing ubiquitin conjugating enzyme regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis
World journal of hepatology, 2021-03, Vol.13 (3), p.343-361
2021
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mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition
Molecular and cellular biology, 2009-09, Vol.29 (18), p.5136-5147
2009
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