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Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage

Blood, 2016-03, Vol.127 (10), p.1242-1248

2016

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Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

Cell stem cell, 2016-07, Vol.19 (1), p.23-37

2016

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ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Cancer cell, 2012-08, Vol.22 (2), p.180-193

2012

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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Cell, 2017-09, Vol.170 (6), p.1079-1095.e20

2017

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miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity

Nature communications, 2015-11, Vol.6 (1), p.8864-8864, Article 8864

2015

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Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

Cell stem cell, 2007-12, Vol.1 (6), p.635-645

2007

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Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

The Journal of experimental medicine, 2013-11, Vol.210 (12), p.2641-2659

2013

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CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Cell, 2009-07, Vol.138 (2), p.271-285

2009

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SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

Cancer cell, 2015-05, Vol.27 (5), p.617-630

2015

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Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (4), p.1374-1384

2011

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Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47

Science translational medicine, 2010-12, Vol.2 (63), p.63ra94

2010

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Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF

Nature communications, 2020-02, Vol.11 (1), p.666-666, Article 666

2020

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Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.3011-3016

2013

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Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.E5401-E5410

2014

Volltextzugriff (PDF)

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Blood, 2019-05, Vol.133 (19), p.2069-2078

2019

Volltextzugriff (PDF)

CD99 is a therapeutic target on disease stem cells in myeloid malignancies

Science translational medicine, 2017-01, Vol.9 (374)

2017

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ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

eLife, 2018-05, Vol.7

2018

Volltextzugriff (PDF)

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

The Journal of experimental medicine, 2010-03, Vol.207 (3), p.475-489

2010

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PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage

Cell reports (Cambridge), 2016-04, Vol.15 (2), p.423-435

2016

Volltextzugriff (PDF)

Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

PloS one, 2023-05, Vol.18 (5), p.e0282722-e0282722

2023

Volltextzugriff (PDF)

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21505-21510

2010

Volltextzugriff (PDF)

FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

eLife, 2019-12, Vol.8

2019

Volltextzugriff (PDF)

Notch pathway activation targets AML-initiating cell homeostasis and differentiation

The Journal of experimental medicine, 2013-02, Vol.210 (2), p.301-319

2013

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Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage

Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47

Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF

Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes

Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells

CD99 is a therapeutic target on disease stem cells in myeloid malignancies

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage

Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets

FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

Notch pathway activation targets AML-initiating cell homeostasis and differentiation

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