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Role of Nrf2 in protection against acute kidney injury

Kidney international, 2013-12, Vol.84 (6), p.1090-1095

2013

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Circulating microRNAs as potential markers of human drug‐induced liver injury

Hepatology (Baltimore, Md.), 2011-11, Vol.54 (5), p.1767-1776

2011

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Mechanistic biomarkers provide early and sensitive detection of acetaminophen‐induced acute liver injury at first presentation to hospital

Hepatology (Baltimore, Md.), 2013-08, Vol.58 (2), p.777-787

2013

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New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.236-244

2015

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Alternatively activated macrophages promote resolution of necrosis following acute liver injury

Journal of hepatology, 2020-08, Vol.73 (2), p.349-360

2020

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Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B13:01

Allergy (Copenhagen), 2019-08, Vol.74 (8), p.1533-1548

2019

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Immune pathomechanism of drug hypersensitivity reactions

Journal of allergy and clinical immunology, 2011-03, Vol.127 (3), p.S74-S81

2011

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The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Toxicology in vitro, 2018-12, Vol.53, p.136-147

2018

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Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes

Journal of the American Society of Nephrology, 2014-10, Vol.25 (10), p.2177-2186

2014

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Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-05, Vol.877 (13), p.1229-1239

2009

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Human leukocyte antigen (HLA)‐B57:01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury

Hepatology (Baltimore, Md.), 2013-02, Vol.57 (2), p.727-739

2013

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Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Biochemical journal, 2012-04, Vol.443 (1), p.213-222

2012

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Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Archives of toxicology, 2017-01, Vol.91 (1), p.439-452

2017

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Mass Spectrometric and Functional Aspects of Drug–Protein Conjugation

Chemical research in toxicology, 2016-12, Vol.29 (12), p.1912-1935

2016

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Assessing the Safety of Stem Cell Therapeutics

Cell stem cell, 2011-06, Vol.8 (6), p.618-628

2011

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Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress

Biochemical Society transactions, 2015-08, Vol.43 (4), p.657-662

2015

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Characterization of amoxicillin‐ and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury

Hepatology (Baltimore, Md.), 2015-09, Vol.62 (3), p.887-899

2015

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The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Toxicology in vitro, 2015-06, Vol.29 (4), p.732-740

2015

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Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4217-4227

2017

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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1699-1710

2016

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Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

Molecular cancer, 2011-04, Vol.10 (1), p.37-37, Article 37

2011

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Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1743-1756

2016

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Managing the challenge of chemically reactive metabolites in drug development

Nature reviews. Drug discovery, 2011-04, Vol.10 (4), p.292-306

2011

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Proteome‐wide analyses of human hepatocytes during differentiation and dedifferentiation

Hepatology (Baltimore, Md.), 2013-08, Vol.58 (2), p.799-809

2013

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Kinetic characterization of bile salt transport by human NTCP (SLC10A1)

Toxicology in vitro, 2018-02, Vol.46, p.189-193

2018

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Role of Nrf2 in protection against acute kidney injury

Circulating microRNAs as potential markers of human drug‐induced liver injury

Mechanistic biomarkers provide early and sensitive detection of acetaminophen‐induced acute liver injury at first presentation to hospital

New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Alternatively activated macrophages promote resolution of necrosis following acute liver injury

Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B13:01

Immune pathomechanism of drug hypersensitivity reactions

The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics

Human leukocyte antigen (HLA)‐B57:01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Mass Spectrometric and Functional Aspects of Drug–Protein Conjugation

Assessing the Safety of Stem Cell Therapeutics

Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress

Characterization of amoxicillin‐ and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury

The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Managing the challenge of chemically reactive metabolites in drug development

Proteome‐wide analyses of human hepatocytes during differentiation and dedifferentiation

Kinetic characterization of bile salt transport by human NTCP (SLC10A1)

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