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Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31

Frontiers in pharmacology, 2024, Vol.15, p.1380655-1380655

2024

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Ion channels and anti-cancer immunity

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2014-03, Vol.369 (1638), p.20130106

2014

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Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (34), p.E8077-E8085

2018

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The Voltage-Gated Hv1 H + Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6216

2023

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KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology

Scientific reports, 2021-07, Vol.11 (1), p.14632-14632, Article 14632

2021

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Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

Pharmaceutics, 2022-11, Vol.14 (12), p.2559

2022

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Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles

Journal of thrombosis and haemostasis, 2022-05, Vol.20 (5), p.1223-1235

2022

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Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy

Frontiers in pharmacology, 2021-01, Vol.11, p.586599-586599

2021

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Peptide Inhibitors of Kv1.5: An Option for the Treatment of Atrial Fibrillation

Pharmaceuticals (Basel, Switzerland), 2021-12, Vol.14 (12), p.1303

2021

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The voltage-gated proton channel hHv1 is functionally expressed in human chorion-derived mesenchymal stem cells

Scientific reports, 2020-04, Vol.10 (1), p.7100-7100, Article 7100

2020

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Pore-modulating toxins exploit inherent slow inactivation to block K⁺ channels

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (37), p.18700-18709

2019

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Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels

Toxicon (Oxford), 2014-09, Vol.87, p.6-16

2014

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Mapping the functional expression of auxiliary subunits of KCa1.1 in glioblastoma

Scientific reports, 2022-12, Vol.12 (1), p.22023-22023, Article 22023

2022

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Cross talk between activation and slow inactivation gates of Shaker potassium channels

The Journal of general physiology, 2006-11, Vol.128 (5), p.547-559

2006

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Optimization of Pichia pastoris Expression System for High-Level Production of Margatoxin

Frontiers in pharmacology, 2021-09, Vol.12, p.733610-733610

2021

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The hEag1 K+ Channel Inhibitor Astemizole Stimulates Ca2+ Deposition in SaOS-2 and MG-63 Osteosarcoma Cultures

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10533

2022

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Periodic Membrane Potential and Ca2+ Oscillations in T Cells Forming an Immune Synapse

International journal of molecular sciences, 2020-02, Vol.21 (5), p.1568

2020

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Of Seven New K+ Channel Inhibitor Peptides of Centruroides bonito, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Toxins, 2023-08, Vol.15 (8), p.506

2023

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Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the KV1.3 Ion Channel Independent of Membrane Cholesterol Extraction

Frontiers in molecular biosciences, 2021-11, Vol.8, p.735357-735357

2021

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Membrane Potential Distinctly Modulates Mobility and Signaling of IL-2 and IL-15 Receptors in T Cells

Biophysical journal, 2018-05, Vol.114 (10), p.2473-2482

2018

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Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides

Cells (Basel, Switzerland), 2023-06, Vol.12 (13), p.1700

2023

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Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

Frontiers in pharmacology, 2021-05, Vol.12, p.592184-592184

2021

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Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K+ Channel KV1.2 and Small- and Intermediate-Conductance Ca2+-Activated K+ Channels KCa2.2 and KCa3.1

Toxins, 2023-01, Vol.15 (1), p.41

2023

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A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

Frontiers in pharmacology, 2021-01, Vol.11, p.563858-563858

2021

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Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31

Ion channels and anti-cancer immunity

Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

The Voltage-Gated Hv1 H + Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells

KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology

Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles

Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy

Peptide Inhibitors of Kv1.5: An Option for the Treatment of Atrial Fibrillation

The voltage-gated proton channel hHv1 is functionally expressed in human chorion-derived mesenchymal stem cells

Pore-modulating toxins exploit inherent slow inactivation to block K⁺ channels

Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels

Mapping the functional expression of auxiliary subunits of KCa1.1 in glioblastoma

Cross talk between activation and slow inactivation gates of Shaker potassium channels

Optimization of Pichia pastoris Expression System for High-Level Production of Margatoxin

The hEag1 K+ Channel Inhibitor Astemizole Stimulates Ca2+ Deposition in SaOS-2 and MG-63 Osteosarcoma Cultures

Periodic Membrane Potential and Ca2+ Oscillations in T Cells Forming an Immune Synapse

Of Seven New K+ Channel Inhibitor Peptides of Centruroides bonito, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the KV1.3 Ion Channel Independent of Membrane Cholesterol Extraction

Membrane Potential Distinctly Modulates Mobility and Signaling of IL-2 and IL-15 Receptors in T Cells

Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K+ Channel KV1.2 and Small- and Intermediate-Conductance Ca2+-Activated K+ Channels KCa2.2 and KCa3.1

Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family

A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

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