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Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.2849

2016

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Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

Nature protocols, 2008-03, Vol.3 (3), p.427-434

2008

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Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

Acta pharmaceutica Sinica. B, 2020-06, Vol.10 (6), p.961-978

2020

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Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells

European journal of medicinal chemistry, 2016-10, Vol.121, p.58-70

2016

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A time-of-drug addition approach to target identification of antiviral compounds

Nature protocols, 2011-06, Vol.6 (6), p.925-933

2011

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Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks

ACS chemical biology, 2017-10, Vol.12 (10), p.2644-2651

2017

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Synthesis and antiviral activity of new pyrazole and thiazole derivatives

European journal of medicinal chemistry, 2009-09, Vol.44 (9), p.3746-3753

2009

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Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

Molecules (Basel, Switzerland), 2017-02, Vol.22 (2), p.303-303

2017

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The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell

International journal of antimicrobial agents, 2016-04, Vol.47 (4), p.311-316

2016

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Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2- d ]pyrimidine non-nucleoside inhibitors

eLife, 2018-07, Vol.7 (2018)

2018

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Fragment-based discovery of sulfur-containing diarylbenzopyrimidines as novel nonnucleoside reverse transcriptase inhibitors

Chinese chemical letters, 2020-03, Vol.31 (3), p.764-768

2020

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Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis

Molecules (Basel, Switzerland), 2023-04, Vol.28 (7), p.3222

2023

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Structure-Based Design of Novel Thiazolone[3,2- a ]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy

Molecules (Basel, Switzerland), 2024-05, Vol.29 (9), p.2120

2024

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Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

European journal of medicinal chemistry, 2021-12, Vol.226, p.113848-113848, Article 113848

2021

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A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication

Journal of medicinal chemistry, 2010-01, Vol.53 (2), p.641-648

2010

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1,2,4-Triazolo[1,5- a ]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

Molecules (Basel, Switzerland), 2020-03, Vol.25 (5), p.1183

2020

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Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy

Molecules (Basel, Switzerland), 2020-02, Vol.25 (5), p.1050

2020

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Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole–Thiourea Scaffold as Antituberculosis Agents

Biological and Pharmaceutical Bulletin, 2016/04/01, Vol.39(4), pp.502-515

2016

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Design strategies of novel NNRTIs to overcome drug resistance

Current medicinal chemistry, 2009-10, Vol.16 (29), p.3903

2009

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Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication

Journal of natural products (Washington, D.C.), 2015-06, Vol.78 (6), p.1277-1283

2015

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Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7538

2022

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Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators

Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7640

2022

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Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction

Molecules (Basel, Switzerland), 2022-09, Vol.27 (18), p.5995

2022

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Covalently Targeted Highly Conserved Tyr318 to Improve the Drug Resistance Profiles of HIV-1 NNRTIs: A Proof-of-Concept Study

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1215

2023

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Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators

Molecules (Basel, Switzerland), 2022-12, Vol.27 (23), p.8415

2022

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Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells

A time-of-drug addition approach to target identification of antiviral compounds

Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2- d ]pyrimidine non-nucleoside inhibitors

Fragment-based discovery of sulfur-containing diarylbenzopyrimidines as novel nonnucleoside reverse transcriptase inhibitors

Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis

Structure-Based Design of Novel Thiazolone[3,2- a ]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication

1,2,4-Triazolo[1,5- a ]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy

Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole–Thiourea Scaffold as Antituberculosis Agents

Design strategies of novel NNRTIs to overcome drug resistance

Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators

Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction

Covalently Targeted Highly Conserved Tyr318 to Improve the Drug Resistance Profiles of HIV-1 NNRTIs: A Proof-of-Concept Study

Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators

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