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Subclasses of angiotensin II binding sites and their functional significance

Molecular pharmacology, 1990-09, Vol.38 (3), p.370-377

1990

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Structure−Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 1997-07, Vol.40 (15), p.2296-2303

1997

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Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4365-4377

1998

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Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain

The EMBO journal, 1998-10, Vol.17 (20), p.5896-5904

1998

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Structure−Activity Relationships for 1-Phenylbenzimidazoles as Selective ATP Site Inhibitors of the Platelet-Derived Growth Factor Receptor

Journal of medicinal chemistry, 1998-12, Vol.41 (27), p.5457-5465

1998

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Synthesis and structure-activity relationships of 7-substituted 3-(2, 6-dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as selective inhibitors of pp60(c-src)

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.3134-3147

2000

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Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Journal of medicinal chemistry, 1999-07, Vol.42 (13), p.2373-2382

1999

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Functional studies but not receptor binding can distinguish surmountable from insurmountable AT1 antagonism

The Journal of pharmacology and experimental therapeutics, 1995-05, Vol.273 (2), p.753

1995

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2-Substituted Aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

Journal of medicinal chemistry, 1998-08, Vol.41 (17), p.3276-3292

1998

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PDGF receptor protein tyrosine kinase expression in the balloon-injured rat carotid artery

Arteriosclerosis, thrombosis, and vascular biology, 1997-07, Vol.17 (7), p.1283

1997

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Design of a functional hexapeptide antagonist of endothelin

Journal of medicinal chemistry, 1992-08, Vol.35 (17), p.3301-3303

1992

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A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

British journal of pharmacology, 1987-06, Vol.91 (2), p.275-286

1987

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Endothelin and structurally related analogs distinguish between endothelin receptor subtypes

Biochemical and biophysical research communications, 1992-03, Vol.183 (2), p.566-571

1992

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Design of Peptidomimetics That Inhibit the Association of Phosphatidylinositol 3-Kinase with Platelet-Derived Growth Factor-β Receptor and Possess Cellular Activity

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4329-4342

1998

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Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.1915-1926

2001

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Multiple binding modes for the receptor-bound conformations of cyclic AII agonists

Journal of medicinal chemistry, 1993-06, Vol.36 (13), p.1902-1913

1993

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Progress in the development of inhibitors of SH2 domains

Current pharmaceutical design, 2000-01, Vol.6 (1), p.59

2000

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Evidence for NO involvement in regulating vascular reactivity in balloon-injured rat carotid artery

American journal of physiology. Heart and circulatory physiology, 1995-09, Vol.269 (3), p.H988-H996

1995

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In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor

The Journal of pharmacology and experimental therapeutics, 1997-12, Vol.283 (3), p.1433

1997

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Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats

The Journal of pharmacology and experimental therapeutics, 1993-04, Vol.265 (1), p.187

1993

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In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase

The Journal of pharmacology and experimental therapeutics, 1998-07, Vol.286 (1), p.569

1998

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Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure

The Journal of pharmacology and experimental therapeutics, 1991-02, Vol.256 (2), p.568

1991

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INHIBITION OF FGF-1 RECEPTOR TYROSINE KINASE ACTIVITY BY PD 161570, A NEW PROTEIN-TYROSINE KINASE INHIBITOR

Life sciences (1973), 1998, Vol.62 (2), p.143-150

1998

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Derivatives of 5-[[1-4(4-carboxybenzyl)imidazolyl]methylidene]hydantoins as orally active angiotensin II receptor antagonists

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3759-3771

1995

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p21-activated Kinase-1 (PAK1) Inhibition of the Human Scavenger Receptor Class B, Type I Promoter in Macrophages Is Independent of PAK1 Kinase Activity, but Requires the GTPase-binding Domain

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.46807-46814

2001

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Subclasses of angiotensin II binding sites and their functional significance

Structure−Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors

Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain

Structure−Activity Relationships for 1-Phenylbenzimidazoles as Selective ATP Site Inhibitors of the Platelet-Derived Growth Factor Receptor

Synthesis and structure-activity relationships of 7-substituted 3-(2, 6-dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as selective inhibitors of pp60(c-src)

Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Functional studies but not receptor binding can distinguish surmountable from insurmountable AT1 antagonism

2-Substituted Aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

PDGF receptor protein tyrosine kinase expression in the balloon-injured rat carotid artery

Design of a functional hexapeptide antagonist of endothelin

A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

Endothelin and structurally related analogs distinguish between endothelin receptor subtypes

Design of Peptidomimetics That Inhibit the Association of Phosphatidylinositol 3-Kinase with Platelet-Derived Growth Factor-β Receptor and Possess Cellular Activity

Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity

Multiple binding modes for the receptor-bound conformations of cyclic AII agonists

Progress in the development of inhibitors of SH2 domains

Evidence for NO involvement in regulating vascular reactivity in balloon-injured rat carotid artery

In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor

Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase

Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure

INHIBITION OF FGF-1 RECEPTOR TYROSINE KINASE ACTIVITY BY PD 161570, A NEW PROTEIN-TYROSINE KINASE INHIBITOR

Derivatives of 5-[[1-4(4-carboxybenzyl)imidazolyl]methylidene]hydantoins as orally active angiotensin II receptor antagonists

p21-activated Kinase-1 (PAK1) Inhibition of the Human Scavenger Receptor Class B, Type I Promoter in Macrophages Is Independent of PAK1 Kinase Activity, but Requires the GTPase-binding Domain

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