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Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug Discovery

Toxicological sciences, 2019-11, Vol.172 (1), p.89-97

2019

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Acute effects of cardiac contractility modulation stimulation in conventional 2D and 3D human induced pluripotent stem cell-derived cardiomyocyte models

Frontiers in physiology, 2022-11, Vol.13, p.1023563-1023563

2022

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Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis

PloS one, 2009-12, Vol.4 (12), p.e8359-e8359

2009

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Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes

Tissue engineering. Part C, Methods, 2011-12, Vol.17 (12), p.1223

2011

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Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes

Haematologica (Roma), 2012-11, Vol.97 (11), p.1657-1665

2012

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Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Haematologica (Roma), 2013-04, Vol.98 (4), p.514-517

2013

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Abstract 11951: Acute Cardiac Contractility Modulation Assessment in Conventional 2D Monolayers and 3D Engineered Cardiac Tissues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Circulation (New York, N.Y.), 2022-11, Vol.146 (Suppl_1)

2022

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Differential gene expression in human, murine, and cell line-derived macrophages upon polarization

Experimental cell research, 2016-09, Vol.347 (1), p.1-13

2016

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Inotropic assessment in engineered 3D cardiac tissues using human induced pluripotent stem cell-derived cardiomyocytes in the BiowireTM II platform

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106886-106886, Article 106886

2020

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BMP protein‐mediated crosstalk between inflammatory cells and human pluripotent stem cell‐derived cardiomyocytes

Journal of tissue engineering and regenerative medicine, 2017-05, Vol.11 (5), p.1466-1478

2017

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Characteristics of platelet gels combined with silk

Biomaterials, 2014-04, Vol.35 (11), p.3678-3687

2014

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Biowire™ II human engineered cardiac tissues have clinically-relevant responses to inotropic agents as measured by the Cardiotype.Fo Assay

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Inotropic assessment in engineered 3D cardiac tissue using human induced pluripotent stem cell-derived cardiomyocytes

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106856, Article 106856

2020

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Use of human induced pluripotent stem cell-derived engineered cardiac tissues to predict cardiotoxic responses to a chemotherapeutic agent

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106821, Article 106821

2020

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BMP protein-mediated crosstalk between inflammatory cells and human pluripotent stem cell-derived cardiomyocytes: BMP protein-mediated crosstalk between macrophages and hESC-CMs

Journal of tissue engineering and regenerative medicine, 2017-05, Vol.11 (5), p.1466-1478

2017

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Contributions of bone morphogenetic proteins in cardiac repair cells in three‐dimensional in vitro models and angiogenesis

Journal of tissue engineering and regenerative medicine, 2018-02, Vol.12 (2), p.349-359

2018

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Extracellular matrix structure and nano-mechanics determine megakaryocyte function

Blood, 2011-10, Vol.118 (16), p.4449-4453

2011

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Biowire™ II matured human engineered 3D cardiac tissue for drug discovery and cardiotoxicity applications

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.124-124

2018

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3D Model of Thrombopoiesis

Blood, 2010-11, Vol.116 (21), p.1609-1609

2010

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Heterozygous Ala156Val Mutation in the GPIb Alpha (Heterozygous Bernard-Soulier Syndrome Type Bolzano) Induces Macrothrombocytopenia by Hampering Proplatelet Formation

Blood, 2008-11, Vol.112 (11), p.1233-1233

2008

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Relationship between JAK2 V617F Mutation Status, Granulocyte CD177 mRNA Expression and CD177 Soluble Protein Level in Patients with Polycythemia Vera

Blood, 2005-11, Vol.106 (11), p.2578-2578

2005

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Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug Discovery

Acute effects of cardiac contractility modulation stimulation in conventional 2D and 3D human induced pluripotent stem cell-derived cardiomyocyte models

Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis

Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes

Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Abstract 11951: Acute Cardiac Contractility Modulation Assessment in Conventional 2D Monolayers and 3D Engineered Cardiac Tissues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Differential gene expression in human, murine, and cell line-derived macrophages upon polarization

Inotropic assessment in engineered 3D cardiac tissues using human induced pluripotent stem cell-derived cardiomyocytes in the BiowireTM II platform

BMP protein‐mediated crosstalk between inflammatory cells and human pluripotent stem cell‐derived cardiomyocytes

Characteristics of platelet gels combined with silk

Biowire™ II human engineered cardiac tissues have clinically-relevant responses to inotropic agents as measured by the Cardiotype.Fo Assay

Inotropic assessment in engineered 3D cardiac tissue using human induced pluripotent stem cell-derived cardiomyocytes

Use of human induced pluripotent stem cell-derived engineered cardiac tissues to predict cardiotoxic responses to a chemotherapeutic agent

BMP protein-mediated crosstalk between inflammatory cells and human pluripotent stem cell-derived cardiomyocytes: BMP protein-mediated crosstalk between macrophages and hESC-CMs

Contributions of bone morphogenetic proteins in cardiac repair cells in three‐dimensional in vitro models and angiogenesis

Extracellular matrix structure and nano-mechanics determine megakaryocyte function

Biowire™ II matured human engineered 3D cardiac tissue for drug discovery and cardiotoxicity applications

3D Model of Thrombopoiesis

Heterozygous Ala156Val Mutation in the GPIb Alpha (Heterozygous Bernard-Soulier Syndrome Type Bolzano) Induces Macrothrombocytopenia by Hampering Proplatelet Formation

Relationship between JAK2 V617F Mutation Status, Granulocyte CD177 mRNA Expression and CD177 Soluble Protein Level in Patients with Polycythemia Vera

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