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Structure Activity of 3-Aryl-1,3-diketo-Containing Compounds as HIV-1 Integrase Inhibitors

Journal of medicinal chemistry, 2002-07, Vol.45 (15), p.3184-3194

2002

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Azido-Containing Diketo Acid Derivatives Inhibit Human Immunodeficiency Virus Type 1 Integrase In Vivo and Influence the Frequency of Deletions at Two-Long-Terminal-Repeat-Circle Junctions

Journal of Virology, 2004-04, Vol.78 (7), p.3210-3222

2004

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Exploration of the Activity of 7-Pyrrolidino-8-methoxyisothiazoloquinolones against Methicillin-Resistant Staphylococcus aureus (MRSA)

Journal of medicinal chemistry, 2011-05, Vol.54 (9), p.3268-3282

2011

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Isothiazoloquinolones with Enhanced Antistaphylococcal Activities against Multidrug-Resistant Strains: Effects of Structural Modifications at the 6-, 7-, and 8-Positions

Journal of medicinal chemistry, 2007-01, Vol.50 (2), p.199-210

2007

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Metal-Dependent Inhibition of HIV-1 Integrase

Journal of medicinal chemistry, 2002-12, Vol.45 (26), p.5661-5670

2002

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Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S)

Molecular pharmacology, 2003-09, Vol.64 (3), p.600-609

2003

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Integration Requires a Specific Interaction of the Donor DNA Terminal 5′-Cytosine with Glutamine 148 of the HIV-1 Integrase Flexible Loop

The Journal of biological chemistry, 2006-01, Vol.281 (1), p.461-467

2006

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Azido-Containing aryl β-Diketo acid HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (6), p.1215-1219

2003

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Practical Synthesis and Molecular Structure of a Potent Broad-Spectrum Antibacterial Isothiazoloquinolone

Organic process research & development, 2007-05, Vol.11 (3), p.389-398

2007

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Efficient Synthesis of the γ-Amino-β-hydroxy Acid Subunit of Hapalosin

Journal of organic chemistry, 1999-06, Vol.64 (12), p.4551-4554

1999

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Utilization of a Peptide Lead for the Discovery of a Novel PTP1B-Binding Motif

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.2869-2878

2001

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Structural Determinants for HIV-1 Integrase Inhibition by β-Diketo Acids

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.12596-12603

2002

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Integration Requires a Specific Interaction of the Donor DNA Terminal 5â²-Cytosine with Glutamine 148 of the HIV-1 Integrase Flexible Loop

The Journal of biological chemistry, 2006-01, Vol.281 (1), p.461

2006

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Hydroxy-assisted chemo- and stereo-selective epoxidation catalysed by a titanium silicate molecular sieve (TS-1)/H2O2 system

Journal of the Chemical Society. Chemical communications, 1995 (13), p.1315

1995

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Metal-Dependent Inhibition of HIV-1 Integrase by Î²-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)

Molecular pharmacology, 2003-09, Vol.64 (3), p.600

2003

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Structural Determinants for HIV-1 Integrase Inhibition by Î²-Diketo Acids

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.12596

2002

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ChemInform Abstract: Efficient Synthesis of the γ-Amino-β-hydroxy Acid Subunit (I) of Hapalosin

ChemInform, 1999-09, Vol.30 (38), p.no-no

1999

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ChemInform Abstract: Asymmetric Synthesis of (S)-Massoialactone

ChemInform, 2000-02, Vol.31 (7), p.no-no

2000

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ChemInform Abstract: Heterogeneous Catalytic Asymmetric Aminohydroxylation of Olefins Using Polymer-Supported Cinchona Alkaloids

ChemInform, 1999-10, Vol.30 (42), p.no-no

1999

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ChemInform Abstract: Total Synthesis of Hapalosin (I) and Two Ring Expanded Analogues (II)

ChemInform, 2001-02, Vol.32 (9), p.no-no

2001

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ChemInform Abstract: Regio- and Stereoselective Hydrogenolysis of Optically Active Diols via Transfer Hydrogenation: Synthesis of α-Arylpropionic Acids

ChemInform, 1999-06, Vol.30 (24), p.no-no

1999

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Azido-Containing Aryl β-Diketo Acid HIV-1 Integrase Inhibitors

ChemInform, 2003-07, Vol.34 (29), p.no-no

2003

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Inhibition of Human Immunodeficiency Virus Type 1 Integration by Diketo Derivatives

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3292-3297

2002

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Structure Activity of 3-Aryl-1,3-diketo-Containing Compounds as HIV-1 Integrase Inhibitors

Azido-Containing Diketo Acid Derivatives Inhibit Human Immunodeficiency Virus Type 1 Integrase In Vivo and Influence the Frequency of Deletions at Two-Long-Terminal-Repeat-Circle Junctions

Exploration of the Activity of 7-Pyrrolidino-8-methoxyisothiazoloquinolones against Methicillin-Resistant Staphylococcus aureus (MRSA)

Isothiazoloquinolones with Enhanced Antistaphylococcal Activities against Multidrug-Resistant Strains: Effects of Structural Modifications at the 6-, 7-, and 8-Positions

Metal-Dependent Inhibition of HIV-1 Integrase

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S)

Integration Requires a Specific Interaction of the Donor DNA Terminal 5′-Cytosine with Glutamine 148 of the HIV-1 Integrase Flexible Loop

Azido-Containing aryl β-Diketo acid HIV-1 integrase inhibitors

Practical Synthesis and Molecular Structure of a Potent Broad-Spectrum Antibacterial Isothiazoloquinolone

Efficient Synthesis of the γ-Amino-β-hydroxy Acid Subunit of Hapalosin

Utilization of a Peptide Lead for the Discovery of a Novel PTP1B-Binding Motif

Structural Determinants for HIV-1 Integrase Inhibition by β-Diketo Acids

Integration Requires a Specific Interaction of the Donor DNA Terminal 5â²-Cytosine with Glutamine 148 of the HIV-1 Integrase Flexible Loop

Hydroxy-assisted chemo- and stereo-selective epoxidation catalysed by a titanium silicate molecular sieve (TS-1)/H2O2 system

Metal-Dependent Inhibition of HIV-1 Integrase by Î²-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)

Structural Determinants for HIV-1 Integrase Inhibition by Î²-Diketo Acids

ChemInform Abstract: Efficient Synthesis of the γ-Amino-β-hydroxy Acid Subunit (I) of Hapalosin

ChemInform Abstract: Asymmetric Synthesis of (S)-Massoialactone

ChemInform Abstract: Heterogeneous Catalytic Asymmetric Aminohydroxylation of Olefins Using Polymer-Supported Cinchona Alkaloids

ChemInform Abstract: Total Synthesis of Hapalosin (I) and Two Ring Expanded Analogues (II)

ChemInform Abstract: Regio- and Stereoselective Hydrogenolysis of Optically Active Diols via Transfer Hydrogenation: Synthesis of α-Arylpropionic Acids

Azido-Containing Aryl β-Diketo Acid HIV-1 Integrase Inhibitors

Inhibition of Human Immunodeficiency Virus Type 1 Integration by Diketo Derivatives

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