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Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy

Neuron (Cambridge, Mass.), 2015-01, Vol.85 (1), p.88-100

2015

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Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

Nature communications, 2019-12, Vol.10 (1), p.5583-20, Article 5583

2019

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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

Frontiers in molecular neuroscience, 2017-08, Vol.10, p.263-263

2017

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Stress granules at the intersection of autophagy and ALS

Brain research, 2016-10, Vol.1649 (Pt B), p.189-200

2016

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Editorial: Drosophila as a model to study neurodegenerative diseases

Frontiers in neuroscience, 2023-08, Vol.17, p.1275253-1275253

2023

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RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration

Neuron (Cambridge, Mass.), 2018-05, Vol.98 (4), p.754-766.e4

2018

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Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo

Neurobiology of disease, 2020-07, Vol.140, p.104837-104837, Article 104837

2020

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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity

Human molecular genetics, 2016-09, Vol.25 (18), p.3908-3924

2016

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

Nature, 2007-06, Vol.447 (7146), p.860-864

2007

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Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans

Human molecular genetics, 2017-12, Vol.26 (24), p.4916-4928

2017

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Matrin-3 dysfunction in myopathy and motor neuron degeneration

Neural regeneration research, 2022-03, Vol.17 (3), p.575-576

2022

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RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

Acta neuropathologica communications, 2020-08, Vol.8 (1), p.138-138, Article 138

2020

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A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43

Human molecular genetics, 2011-07, Vol.20 (13), p.2510-2523

2011

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LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice

Nature communications, 2023-02, Vol.14 (1), p.603-22, Article 603

2023

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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

eLife, 2021-06, Vol.10

2021

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Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS

Human molecular genetics, 2018-01, Vol.27 (2), p.322-337

2018

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Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

PloS one, 2013-04, Vol.8 (4), p.e61576

2013

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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Stem cell reports, 2018-02, Vol.10 (2), p.375-389

2018

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Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2

eLife, 2023-04, Vol.12

2023

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Further delineation of GEMIN4 related neurodevelopmental disorder with microcephaly, cataract, and renal abnormalities syndrome

American journal of medical genetics. Part A, 2022-10, Vol.188 (10), p.2932-2940

2022

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Skeletal Muscle Pathogenesis in Polyglutamine Diseases

Cells (Basel, Switzerland), 2022-07, Vol.11 (13), p.2105

2022

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HDAC6 at the Intersection of Autophagy, the Ubiquitin-proteasome System, and Neurodegeneration

Autophagy, 2007-11, Vol.3 (6), p.643-645

2007

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RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

Acta neuropathologica communications, 2020-10, Vol.8 (1), p.177-20, Article 177

2020

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Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand

Stress granules at the intersection of autophagy and ALS

Editorial: Drosophila as a model to study neurodegenerative diseases

RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans

Matrin-3 dysfunction in myopathy and motor neuron degeneration

RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43

LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice

Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS

Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2

Further delineation of GEMIN4 related neurodevelopmental disorder with microcephaly, cataract, and renal abnormalities syndrome

Skeletal Muscle Pathogenesis in Polyglutamine Diseases

Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo

HDAC6 at the Intersection of Autophagy, the Ubiquitin-proteasome System, and Neurodegeneration

RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

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