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Gene therapy comes of age

Science (American Association for the Advancement of Science), 2018-01, Vol.359 (6372)

2018

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Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex

Neuroscience research, 2015-04, Vol.93, p.144-157

2015

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Professor Shigetaka Asano: extraordinary Japanese haematologist and bon vivant February 7, 1943 to August 12, 2020

Leukemia, 2020-11, Vol.34 (11), p.3107-3108

2020

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Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance

The Journal of neuroscience, 2014-12, Vol.34 (49), p.16273-16285

2014

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CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

Scientific reports, 2017-06, Vol.7 (1), p.4159-11, Article 4159

2017

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Professor Shigetaka Asano: extraordinary Japanese Haematologist and Bon Vivant February 7, 1943 to August 12, 2020

Bone marrow transplantation (Basingstoke), 2021-03, Vol.56 (3), p.751-752

2021

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Cancer gene therapy using mesenchymal stem cells

International journal of hematology, 2014-04, Vol.99 (4), p.377-382

2014

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Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture

Journal of comparative neurology (1911), 2022-08, Vol.530 (11), p.1950-1965

2022

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Regulatory approval pathways for anticancer drugs in Japan, the EU and the US

International Journal of Hematology, 2016-07, Vol.104 (1), p.73-84

2016

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Drug approval based on randomized phase 3 trials for relapsed malignancy: analysis of oncologic drugs granted accelerated approval, publications and clinical trial databases

Investigational new drugs, 2018-06, Vol.36 (3), p.487-495

2018

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A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease

Molecular therapy, 2010-09, Vol.18 (9), p.1731-1735

2010

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Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study

International journal of hematology, 2013-08, Vol.98 (2), p.206-213

2013

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New Japanese Regulatory Frameworks for Clinical Research and Marketing Authorization of Gene Therapy and Cellular Therapy Products

Current gene therapy, 2017-02, Vol.17 (1), p.17

2017

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Long-Term Two-Photon Calcium Imaging of Neuronal Populations with Subcellular Resolution in Adult Non-human Primates

Cell reports (Cambridge), 2015-12, Vol.13 (9), p.1989-1999

2015

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Bone marrow-derived mesenchymal stem cells (JR-031) for steroid-refractory grade III or IV acute graft-versus-host disease: a phase II/III study

International journal of hematology, 2016-02, Vol.103 (2), p.243-250

2016

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Presynaptic dysregulation of the paraventricular thalamic nucleus causes depression-like behavior

Scientific reports, 2019-11, Vol.9 (1), p.16506-9, Article 16506

2019

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Corticospinal tract development and spinal cord innervation differ between cervical and lumbar targets

The Journal of neuroscience, 2015-01, Vol.35 (3), p.1181-1191

2015

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The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice

European journal of haematology, 2014-08, Vol.93 (2), p.118-128

2014

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Comprehensive analysis of clinical development and regulatory submission promotion schemes for oncologic drugs as the Japanese national projects

Investigational new drugs, 2016-12, Vol.34 (6), p.777-791

2016

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Persistent Expression of Dopamine-Synthesizing Enzymes 15 Years After Gene Transfer in a Primate Model of Parkinson's Disease

Human gene therapy. Clinical development, 2017-06, Vol.28 (2), p.74

2017

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Oxytocin Receptor in the Hypothalamus Is Sufficient to Rescue Normal Thermoregulatory Function in Male Oxytocin Receptor Knockout Mice

Endocrinology (Philadelphia), 2013-11, Vol.154 (11), p.4305-4315

2013

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Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma

Blood, 2010-07, Vol.116 (3), p.406-417

2010

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Mesenchymal Stromal Cells for Graft-Versus-Host Disease : Basic Aspects and Clinical Outcomes

Journal of Clinical and Experimental Hematopathology, 2010, Vol.50(2), pp.79-89

2010

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Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy

The journal of gene medicine, 2009-05, Vol.11 (5), p.373-381

2009

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The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals

Journal of medical virology, 2014-11, Vol.86 (11), p.1990-1997

2014

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Gene therapy comes of age

Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex

Professor Shigetaka Asano: extraordinary Japanese haematologist and bon vivant February 7, 1943 to August 12, 2020

Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance

CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

Professor Shigetaka Asano: extraordinary Japanese Haematologist and Bon Vivant February 7, 1943 to August 12, 2020

Cancer gene therapy using mesenchymal stem cells

Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture

Regulatory approval pathways for anticancer drugs in Japan, the EU and the US

Drug approval based on randomized phase 3 trials for relapsed malignancy: analysis of oncologic drugs granted accelerated approval, publications and clinical trial databases

A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease

Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study

New Japanese Regulatory Frameworks for Clinical Research and Marketing Authorization of Gene Therapy and Cellular Therapy Products

Long-Term Two-Photon Calcium Imaging of Neuronal Populations with Subcellular Resolution in Adult Non-human Primates

Bone marrow-derived mesenchymal stem cells (JR-031) for steroid-refractory grade III or IV acute graft-versus-host disease: a phase II/III study

Presynaptic dysregulation of the paraventricular thalamic nucleus causes depression-like behavior

Corticospinal tract development and spinal cord innervation differ between cervical and lumbar targets

The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice

Comprehensive analysis of clinical development and regulatory submission promotion schemes for oncologic drugs as the Japanese national projects

Persistent Expression of Dopamine-Synthesizing Enzymes 15 Years After Gene Transfer in a Primate Model of Parkinson's Disease

Oxytocin Receptor in the Hypothalamus Is Sufficient to Rescue Normal Thermoregulatory Function in Male Oxytocin Receptor Knockout Mice

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma

Mesenchymal Stromal Cells for Graft-Versus-Host Disease : Basic Aspects and Clinical Outcomes

Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy

The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals

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