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A Five-Step Synthesis of (S)-Macrostomine from (S)-Nicotine

Organic letters, 2010-10, Vol.12 (20), p.4513-4515

2010

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Interactions between 2′‐fluoro‐(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine‐binding protein inform on potent antagonist activity against nicotinic receptors

Acta crystallographica. Section D, Biological crystallography., 2022-03, Vol.78 (3), p.353-362

2022

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Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑7-Hydroxy‑N‑[(1S)‑2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic)

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7525-7545

2018

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Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑N‑[1R)‑1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7546-7559

2018

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Synthesis of Fused-Ring Nicotine Derivatives from (S)-Nicotine

Journal of organic chemistry, 2010-03, Vol.75 (5), p.1706-1716

2010

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2′-Fluoro-3′-(substituted pyridinyl)-7-deschloroepibatidine Analogues

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.836-848

2014

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Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists

ACS medicinal chemistry letters, 2017-07, Vol.8 (7), p.742-745

2017

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Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (17), p.5693-5701

2015

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Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues

ACS chemical neuroscience, 2016-07, Vol.7 (7), p.1004-1012

2016

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

ACS chemical neuroscience, 2017-01, Vol.8 (1), p.115-127

2017

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Synthesis and regioselective substitution of C-6 alkoxy derivatives of ( S)-nicotine

Tetrahedron letters, 2008-01, Vol.49 (3), p.569-572

2008

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Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Cell, 2018-01, Vol.172 (1-2), p.55-67.e15

2018

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Synthesis and Nicotinic Acetylcholine Receptor in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-3′-(substituted phenyl)deschloroepibatidine Analogues of 2′-Fluoro-3′-(4-nitrophenyl)deschloroepibatidine

Journal of medicinal chemistry, 2012-07, Vol.55 (14), p.6512-6522

2012

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Enhanced electrodetection of ascorbic acid in Adansonia digitata fruit by use of surface modified electrodes

Catalysis letters, 2001-01, Vol.72 (1-2), p.125-128

2001

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A Five-Step Synthesis of (S)-Macrostomine from (S)-Nicotine

Interactions between 2′‐fluoro‐(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine‐binding protein inform on potent antagonist activity against nicotinic receptors

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑7-Hydroxy‑N‑[(1S)‑2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic)

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑N‑[1R)‑1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic

Synthesis of Fused-Ring Nicotine Derivatives from (S)-Nicotine

Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2′-Fluoro-3′-(substituted pyridinyl)-7-deschloroepibatidine Analogues

Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists

Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Synthesis and regioselective substitution of C-6 alkoxy derivatives of ( S)-nicotine

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Synthesis and Nicotinic Acetylcholine Receptor in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-3′-(substituted phenyl)deschloroepibatidine Analogues of 2′-Fluoro-3′-(4-nitrophenyl)deschloroepibatidine

Enhanced electrodetection of ascorbic acid in Adansonia digitata fruit by use of surface modified electrodes

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