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Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors

Neuron (Cambridge, Mass.), 2014-03, Vol.81 (5), p.1084-1096

2014

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Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

PLoS genetics, 2017-01, Vol.13 (1), p.e1006536-e1006536

2017

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Glutamate receptor ion channels: structure, regulation, and function

Pharmacological reviews, 2010-09, Vol.62 (3), p.405-496

2010

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Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain

The Journal of neuroscience, 2009-09, Vol.29 (39), p.12045-12058

2009

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Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors

Molecular pharmacology, 2013-05, Vol.83 (5), p.1045-1056

2013

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GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity

Molecular pharmacology, 2016-12, Vol.90 (6), p.689-702

2016

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Prioritizing the development of mouse models for childhood brain disorders

Neuropharmacology, 2016-01, Vol.100, p.2-16

2016

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A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

Nature communications, 2010-10, Vol.1 (7), p.1-8, Article 90

2010

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Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

Molecular pharmacology, 2011-11, Vol.80 (5), p.782-795

2011

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New advances in NMDA receptor pharmacology

Trends in pharmacological sciences (Regular ed.), 2011-12, Vol.32 (12), p.726-733

2011

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Subunit-selective allosteric inhibition of glycine binding to NMDA receptors

The Journal of neuroscience, 2012-05, Vol.32 (18), p.6197-6208

2012

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NMDA receptor channel gating control by the pre-M1 helix

The Journal of general physiology, 2020-04, Vol.152 (4)

2020

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Potentiation of GluN2C/D NMDA Receptor Subtypes in the Amygdala Facilitates the Retention of Fear and Extinction Learning in Mice

Neuropsychopharmacology (New York, N.Y.), 2014-02, Vol.39 (3), p.625-637

2014

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A structurally derived model of subunit‐dependent NMDA receptor function

The Journal of physiology, 2018-09, Vol.596 (17), p.4057-4089

2018

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Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors

Molecular pharmacology, 2013-07, Vol.84 (1), p.114-127

2013

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Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N‑Methyl‑d‑aspartate Receptors

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5351-5381

2013

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The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta

The Journal of pharmacology and experimental therapeutics, 2007-11, Vol.323 (2), p.606-613

2007

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Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N -Methyl-d-aspartate Receptors

ACS chemical neuroscience, 2021-01, Vol.12 (1), p.79-98

2021

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Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

The Journal of pharmacology and experimental therapeutics, 2010-06, Vol.333 (3), p.650-662

2010

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Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N‑Methyl‑d‑aspartate Receptors

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4975-4975

2014

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Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy

Biophysical journal, 2017-02, Vol.112 (3), p.420a-421a

2017

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A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors

Biophysical journal, 2014-01, Vol.106 (2), p.150a-150a

2014

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Activation of Recombinant Rat GluN1/gluN2D NMDA Receptors

Biophysical journal, 2010-01, Vol.98 (3), p.525a-525a

2010

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Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective ModulatorsS

Molecular pharmacology, 2011-11, Vol.80 (5), p.782-795

2011

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ASHP Guidelines on Preventing Diversion of Controlled Substances

American journal of health-system pharmacy, 2017-03, Vol.74 (5), p.325-348

2017

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Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

Glutamate receptor ion channels: structure, regulation, and function

Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain

Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors

GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity

Prioritizing the development of mouse models for childhood brain disorders

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

New advances in NMDA receptor pharmacology

Subunit-selective allosteric inhibition of glycine binding to NMDA receptors

NMDA receptor channel gating control by the pre-M1 helix

Potentiation of GluN2C/D NMDA Receptor Subtypes in the Amygdala Facilitates the Retention of Fear and Extinction Learning in Mice

A structurally derived model of subunit‐dependent NMDA receptor function

Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors

Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N‑Methyl‑d‑aspartate Receptors

The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N -Methyl-d-aspartate Receptors

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N‑Methyl‑d‑aspartate Receptors

Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy

A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors

Activation of Recombinant Rat GluN1/gluN2D NMDA Receptors

Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective ModulatorsS

ASHP Guidelines on Preventing Diversion of Controlled Substances

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