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Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

PLoS pathogens, 2017-11, Vol.13 (11), p.e1006687-e1006687

2017

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Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

Molecular therapy. Nucleic acids, 2014-10, Vol.3 (10), p.e201-e201, Article e201

2014

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Elucidating novel serum biomarkers associated with pulmonary tuberculosis treatment

PloS one, 2013-04, Vol.8 (4), p.e61002-e61002

2013

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Systematic selection of modified aptamer pairs for diagnostic sandwich assays

BioTechniques, 2014-03, Vol.56 (3), p.125-133

2014

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Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection

Journal of clinical microbiology, 2017-02, Vol.55 (2), p.391-402

2017

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Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

Frontiers in microbiology, 2018-09, Vol.9, p.2231-2231

2018

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Identification of Tandem Duplicate Regulatory Small RNAs in Pseudomonas aeruginosa Involved in Iron Homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (26), p.9792-9797

2004

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GeneChip® expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes

Molecular microbiology, 2002-09, Vol.45 (5), p.1277-1287

2002

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Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis

Tuberculosis (Edinburgh, Scotland), 2014-05, Vol.94 (3), p.187-196

2014

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The response of Pseudomonas aeruginosa to iron: genetics, biochemistry and virulence

Molecular microbiology, 1999-11, Vol.34 (3), p.399-413

1999

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Anaerobic metabolism and quorum sensing by Pseudomonas aeruginosa biofilms in chronically infected cystic fibrosis airways: rethinking antibiotic treatment strategies and drug targets

Advanced drug delivery reviews, 2002-12, Vol.54 (11), p.1425-1443

2002

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Effects of the Twin-Arginine Translocase on Secretion of Virulence Factors, Stress Response, and Pathogenesis

Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (12), p.8312-8317

2002

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FpvB, an alternative type I ferripyoverdine receptor of Pseudomonas aeruginosa

Microbiology (Society for General Microbiology), 2004-06, Vol.150 (Pt 6), p.1671-1680

2004

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Autoinducer-Mediated Regulation of Rhamnolipid Biosurfactant Synthesis in Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences - PNAS, 1995-07, Vol.92 (14), p.6424-6428

1995

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Discovery and Analysis of 4H-Pyridopyrimidines, a Class of Selective Bacterial Protein Synthesis Inhibitors

Antimicrobial Agents and Chemotherapy, 2010-11, Vol.54 (11), p.4648-4657

2010

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Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity

Antimicrobial Agents and Chemotherapy, 2009-01, Vol.53 (1), p.86-94

2009

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Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis

Journal of clinical microbiology, 2017-10, Vol.55 (10), p.3057-3071

2017

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Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF‑8 with Modified DNA Aptamers

Biochemistry (Easton), 2019-11, Vol.58 (46), p.4632-4640

2019

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Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated Listeria monocytogenes intracellular hollow-fibre model

Journal of antimicrobial chemotherapy, 2022-09, Vol.77 (10), p.2876-2885

2022

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Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers

Diagnostic microbiology and infectious disease, 2013-07, Vol.76 (3), p.278-285

2013

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Periplasmic Superoxide Dismutase Protects Salmonella from Products of Phagocyte NADPH-Oxidase and Nitric Oxide Synthase

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (25), p.13997-14001

1997

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Transient Loss of High-Level Mupirocin Resistance in Staphylococcus aureus Due to MupA Polymorphism

Antimicrobial Agents and Chemotherapy, 2007-06, Vol.51 (6), p.2247-2248

2007

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Antibacterial Activity of REP8839, a New Antibiotic for Topical Use

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4247-4252

2005

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Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota

Antimicrobial agents and chemotherapy, 2019-12, Vol.64 (1)

2019

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Safety, Tolerability, Systemic Exposure, and Metabolism of CRS3123, a Methionyl-tRNA Synthetase Inhibitor Developed for Treatment of Clostridium difficile, in a Phase 1 Study

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

Elucidating novel serum biomarkers associated with pulmonary tuberculosis treatment

Systematic selection of modified aptamer pairs for diagnostic sandwich assays

Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

Identification of Tandem Duplicate Regulatory Small RNAs in Pseudomonas aeruginosa Involved in Iron Homeostasis

GeneChip® expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes

Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis

The response of Pseudomonas aeruginosa to iron: genetics, biochemistry and virulence

Anaerobic metabolism and quorum sensing by Pseudomonas aeruginosa biofilms in chronically infected cystic fibrosis airways: rethinking antibiotic treatment strategies and drug targets

Effects of the Twin-Arginine Translocase on Secretion of Virulence Factors, Stress Response, and Pathogenesis

FpvB, an alternative type I ferripyoverdine receptor of Pseudomonas aeruginosa

Autoinducer-Mediated Regulation of Rhamnolipid Biosurfactant Synthesis in Pseudomonas aeruginosa

Discovery and Analysis of 4H-Pyridopyrimidines, a Class of Selective Bacterial Protein Synthesis Inhibitors

Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity

Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis

Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF‑8 with Modified DNA Aptamers

Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated Listeria monocytogenes intracellular hollow-fibre model

Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers

Periplasmic Superoxide Dismutase Protects Salmonella from Products of Phagocyte NADPH-Oxidase and Nitric Oxide Synthase

Transient Loss of High-Level Mupirocin Resistance in Staphylococcus aureus Due to MupA Polymorphism

Antibacterial Activity of REP8839, a New Antibiotic for Topical Use

Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota

Safety, Tolerability, Systemic Exposure, and Metabolism of CRS3123, a Methionyl-tRNA Synthetase Inhibitor Developed for Treatment of Clostridium difficile, in a Phase 1 Study

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