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Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

Clinical pharmacokinetics, 2015-07, Vol.54 (7), p.709-735

2015

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Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)

PloS one, 2011-07, Vol.6 (7), p.e22163

2011

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Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation

Pharmacology & therapeutics (Oxford), 2022-10, Vol.238, p.108268-108268, Article 108268

2022

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Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

Handbook of experimental pharmacology, 2011-01 (201), p.105

2011

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Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors

Trends in pharmacological sciences (Regular ed.), 2016-11, Vol.37 (11), p.904-932

2016

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Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

Trends in pharmacological sciences (Regular ed.), 2013-02, Vol.34 (2), p.126-135

2013

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Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

Hepatology (Baltimore, Md.), 2009-10, Vol.50 (4), p.1227-1240

2009

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A phosphotyrosine switch regulates organic cation transporters

Nature communications, 2016-03, Vol.7 (1), p.10880-10880, Article 10880

2016

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Role of ABC Transporters in Fluoropyrimidine-Based Chemotherapy Response

ABC Transporters and Cancer, 2015, Vol.125, p.217-243

2015

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Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors

Fundamental & clinical pharmacology, 2021-10, Vol.35 (5), p.919-929

2021

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Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation

Pharmacological research, 2023-10, Vol.196, p.106941-106941, Article 106941

2023

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ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (24), p.11419-11428

2005

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Expression and immunolocalization of the multidrug resistance proteins, MRP1–MRP6 (ABCC1–ABCC6), in human brain

Neuroscience, 2004, Vol.129 (2), p.349-360

2004

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Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters

Pharmaceutics, 2021-03, Vol.13 (3), p.369

2021

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The role of membrane transporters in drug delivery to brain tumors

Cancer letters, 2007-08, Vol.254 (1), p.11-29

Nies, Anne T

2007

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A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

American journal of physiology: Gastrointestinal and liver physiology, 2000-01, Vol.278 (1), p.G156-G164

2000

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Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7468

2022

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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

BBA - Biomembranes, 1999-12, Vol.1461 (2), p.377-394

1999

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Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

Clinical pharmacokinetics, 2016-05, Vol.55 (5), p.507-524

2016

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Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide

The Journal of biological chemistry, 2000-07, Vol.275 (30), p.23161-23168

2000

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Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics

Drug metabolism reviews, 2011-11, Vol.43 (4), p.499-523

2011

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Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma

International journal of cancer, 2005-06, Vol.115 (3), p.359-367

2005

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The importance of drug transporter characterization to precision medicine

Expert opinion on drug metabolism & toxicology, 2017-04, Vol.13 (4), p.361-365

2017

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Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

The pharmacogenomics journal, 2016-08, Vol.16 (4), p.341-351

2016

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Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1)

Naunyn-Schmiedeberg's archives of pharmacology, 2008-02, Vol.376 (6), p.449-461

2008

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Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)

Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors

Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

A phosphotyrosine switch regulates organic cation transporters

Role of ABC Transporters in Fluoropyrimidine-Based Chemotherapy Response

Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors

Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation

ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier

Expression and immunolocalization of the multidrug resistance proteins, MRP1–MRP6 (ABCC1–ABCC6), in human brain

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters

The role of membrane transporters in drug delivery to brain tumors

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide

Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics

Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma

The importance of drug transporter characterization to precision medicine

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1)

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