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An EDS1 heterodimer signalling surface enforces timely reprogramming of immunity genes in Arabidopsis

Nature communications, 2019-02, Vol.10 (1), p.772-772, Article 772

2019

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Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity

The New phytologist, 2011-07, Vol.191 (1), p.107-119

2011

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Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design

Biochimica et biophysica acta, 2010-03, Vol.1804 (3), p.484-492

2010

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The Structure of a Bacterial l-Amino Acid Oxidase from Rhodococcus opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation

Journal of molecular biology, 2007-03, Vol.367 (1), p.234-248

2007

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Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile

Catalysts, 2020-11, Vol.10 (11), p.1281

2020

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Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin

European journal of medicinal chemistry, 2021-03, Vol.214, p.113223, Article 113223

2021

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Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70‐1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners

FASEB bioAdvances, 2023-03, Vol.5 (3), p.114-130

2023

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Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination

Biological chemistry, 2013-11, Vol.394 (11), p.1505-1516

2013

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Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2α Lys198Arg

Frontiers in molecular biosciences, 2022-04, Vol.9, p.831693-831693

2022

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Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity

Journal of molecular biology, 2005-06, Vol.349 (4), p.801-813

2005

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The Three-Dimensional Structure of AKR11B4, a Glycerol Dehydrogenase from Gluconobacter oxydans, Reveals a Tryptophan Residue as an Accelerator of Reaction Turnover

Journal of molecular biology, 2010-12, Vol.404 (3), p.353-362

2010

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The Protein Kinase CK2Andante Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation

Journal of molecular biology, 2014-05, Vol.426 (9), p.1871-1882

2014

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Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α

Pharmaceuticals (Basel, Switzerland), 2017-12, Vol.10 (4), p.98

2017

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The Crystal Structure of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Suggests the Structural Basis of its Metal Dependency

Journal of molecular biology, 2003-03, Vol.327 (2), p.317-328

2003

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Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

ACS omega, 2019-03, Vol.4 (3), p.5471-5478

2019

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A π-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors

Pharmaceuticals (Basel, Switzerland), 2018-02, Vol.11 (1), p.23

2018

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Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor

Pharmaceuticals (Basel, Switzerland), 2017-01, Vol.10 (1), p.9

2017

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Inclining the Purine Base Binding Plane in Protein Kinase CK2 by Exchanging the Flanking Side-chains Generates a Preference for ATP as a Cosubstrate

Journal of molecular biology, 2005-03, Vol.347 (2), p.399-414

2005

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Structural Basis of the Constitutive Activity of Protein Kinase CK2

Constitutive Activity in Receptors and Other Proteins, Part A, 2010, Vol.484, p.515-529

2010

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Crystal Structure of a C-terminal Deletion Mutant of Human Protein Kinase CK2 Catalytic Subunit

Journal of molecular biology, 2003-07, Vol.330 (5), p.925-934

2003

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Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity

Cell host & microbe, 2013-12, Vol.14 (6), p.619-630

2013

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A splicing variant of EDS1 from Vitis vinifera forms homodimers but no heterodimers with PAD4

Protein science, 2023-04, Vol.32 (4), p.e4624-n/a

2023

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Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2‑Aminothiazole Compounds on Protein Kinase CK2

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7766-7772

2020

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The Structure of l-Hydantoinase from Arthobacter aurescens Leads to an Understanding of Dihydropyrimidinase Substrate and Enantio Specificity

Biochemistry (Easton), 2002-07, Vol.41 (27), p.8589-8597

2002

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An EDS1 heterodimer signalling surface enforces timely reprogramming of immunity genes in Arabidopsis

Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity

Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design

The Structure of a Bacterial l-Amino Acid Oxidase from Rhodococcus opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation

Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile

Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin

Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70‐1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners

Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination

Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2α Lys198Arg

Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity

The Three-Dimensional Structure of AKR11B4, a Glycerol Dehydrogenase from Gluconobacter oxydans, Reveals a Tryptophan Residue as an Accelerator of Reaction Turnover

The Protein Kinase CK2Andante Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α

De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway

The Crystal Structure of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Suggests the Structural Basis of its Metal Dependency

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

A π-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor

Inclining the Purine Base Binding Plane in Protein Kinase CK2 by Exchanging the Flanking Side-chains Generates a Preference for ATP as a Cosubstrate

Structural Basis of the Constitutive Activity of Protein Kinase CK2

Crystal Structure of a C-terminal Deletion Mutant of Human Protein Kinase CK2 Catalytic Subunit

Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity

A splicing variant of EDS1 from Vitis vinifera forms homodimers but no heterodimers with PAD4

Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2‑Aminothiazole Compounds on Protein Kinase CK2

The Structure of l-Hydantoinase from Arthobacter aurescens Leads to an Understanding of Dihydropyrimidinase Substrate and Enantio Specificity

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