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Activation of autophagy protects against acetaminophen-induced hepatotoxicity

Hepatology (Baltimore, Md.), 2012-01, Vol.55 (1), p.222-232

2012

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Mitochondrial dynamics and mitochondrial quality control

Redox biology, 2015-04, Vol.4 (C), p.6-13

2015

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p53 Up‐regulated Modulator of Apoptosis Induction Mediates Acetaminophen‐Induced Necrosis and Liver Injury in Mice

Hepatology (Baltimore, Md.), 2019-05, Vol.69 (5), p.2164-2179

2019

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Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen‐induced hepatocyte necrosis in mice

Hepatology (Baltimore, Md.), 2013-12, Vol.58 (6), p.2099-2108

2013

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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

Gastroenterology (New York, N.Y. 1943), 2018-09, Vol.155 (3), p.865-879.e12

2018

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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Nature communications, 2020-07, Vol.11 (1), p.3612-16, Article 3612

2020

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Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity

The American journal of pathology, 2013-12, Vol.183 (6), p.1815-1825

2013

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Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Hepatology (Baltimore, Md.), 2023-01, Vol.77 (1), p.159-175

2023

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Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice

American journal of physiology: Gastrointestinal and liver physiology, 2015-09, Vol.309 (5), p.G324-G340

2015

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Removal of Acetaminophen-Protein Adducts by Autophagy Protects Against Acetaminophen-Induced Liver Injury in Mice

Journal of hepatology, 2016-08, Vol.65 (2), p.354-362

2016

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Dual Roles of Mammalian Target of Rapamycin in Regulating Liver Injury and Tumorigenesis in Autophagy‐Defective Mouse Liver

Hepatology (Baltimore, Md.), 2019-12, Vol.70 (6), p.2142-2155

2019

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Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol‐impaired TFEB and liver injury in mice

Alcoholism, clinical and experimental research, 2021-10, Vol.45 (10), p.1950-1964

2021

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Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

The Journal of biological chemistry, 2010-09, Vol.285 (36), p.27879-27890

2010

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Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy

Journal of hepatology, 2022-03, Vol.76 (3), p.639-651

2022

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Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

Gastroenterology (New York, N.Y. 1943), 2010-11, Vol.139 (5), p.1740-1752

2010

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Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

The Journal of pharmacology and experimental therapeutics, 2011-11, Vol.339 (2), p.487

2011

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Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

The American journal of pathology, 2019-07, Vol.189 (7), p.1363-1374

2019

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Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis

The American journal of pathology, 2022-01, Vol.192 (1), p.87-103

2022

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Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

Autophagy, 2011-02, Vol.7 (2), p.188-204

2011

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Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability

The American journal of pathology, 2007-08, Vol.171 (2), p.513-524

2007

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The emerging role of autophagy in alcoholic liver disease

Experimental Biology and Medicine, 2011-05, Vol.236 (5), p.546-556

2011

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Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism

Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2273

2021

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Loss of hepatic VMP1 trapped VLDL in the bilayer of endoplasmic reticulum membrane

Liver research, 2023-06, Vol.7 (2), p.161-163

2023

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Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

Redox biology, 2019-04, Vol.22, p.101148, Article 101148

2019

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Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury

Toxicological sciences, 2012-06, Vol.127 (2), p.438-450

2012

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Activation of autophagy protects against acetaminophen-induced hepatotoxicity

Mitochondrial dynamics and mitochondrial quality control

p53 Up‐regulated Modulator of Apoptosis Induction Mediates Acetaminophen‐Induced Necrosis and Liver Injury in Mice

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen‐induced hepatocyte necrosis in mice

Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity

Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice

Removal of Acetaminophen-Protein Adducts by Autophagy Protects Against Acetaminophen-Induced Liver Injury in Mice

Dual Roles of Mammalian Target of Rapamycin in Regulating Liver Injury and Tumorigenesis in Autophagy‐Defective Mouse Liver

Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol‐impaired TFEB and liver injury in mice

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability

The emerging role of autophagy in alcoholic liver disease

Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism

Loss of hepatic VMP1 trapped VLDL in the bilayer of endoplasmic reticulum membrane

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury

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