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Using medical claims database to develop a population disease progression model for leuprorelin-treated subjects with hormone-sensitive prostate cancer

PloS one, 2020-03, Vol.15 (3), p.e0230571-e0230571

2020

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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Rational Clinical Dose Selection of Adeno‐Associated Virus‐Mediated Gene Therapy Based on Allometric Principles

Clinical pharmacology and therapeutics, 2021-09, Vol.110 (3), p.803-807

2021

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Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

Clinical and translational science, 2021-07, Vol.14 (4), p.1231-1249

2021

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Population Pharmacokinetics of Rituximab (Anti-CD20 Monoclonal Antibody) in Rheumatoid Arthritis Patients During a Phase II Clinical Trial

Journal of clinical pharmacology, 2005-07, Vol.45 (7), p.792-801

2005

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Target-mediated drug disposition model for drugs with N > 2 binding sites that bind to a target with one binding site

Journal of pharmacokinetics and pharmacodynamics, 2024-04

2024

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GPU-accelerated compartmental modeling analysis of DCE-MRI data from glioblastoma patients treated with bevacizumab

PloS one, 2015-03, Vol.10 (3), p.e0118421-e0118421

2015

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A Modified Hybrid Wald’s Approximation Method for Efficient Covariate Selection in Population Pharmacokinetic Analysis

The AAPS journal, 2021-03, Vol.23 (2), p.37-37, Article 37

2021

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Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis

Pharmaceutical research, 2006-06, Vol.23 (6), p.1275-1284

2006

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General quasi-equilibrium multivalent binding model to study diverse and complex drug-receptor interactions of biologics

Journal of pharmacokinetics and pharmacodynamics, 2024-08

2024

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Southeast Asian Affairs 1988

M. Ayoob, Chee Yuen Ng, M. Ayoob, Chee Yuen Ng

2018

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Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers

Pharmaceutical research, 2006, Vol.23 (1), p.95-103

2006

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Oxaliplatin Pharmacokinetics and Pharmacodynamics in Adult Cancer Patients with Impaired Renal Function

Clinical cancer research, 2007-08, Vol.13 (16), p.4832-4839

2007

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Incorporation of FcRn-mediated disposition model to describe the population pharmacokinetics of therapeutic monoclonal IgG antibody in clinical patients

Biopharmaceutics & drug disposition, 2016-03, Vol.37 (2), p.107-119

Ng, Chee M.

2016

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Validation of a HPLC/MS method for simultaneous quantification of clonidine, morphine and its metabolites in human plasma

Biomedical chromatography, 2019-07, Vol.33 (7), p.e4527-n/a

2019

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Population pharmacokinetic analysis of AR-67, a lactone stable camptothecin analogue, in cancer patients with solid tumors

Investigational new drugs, 2019-12, Vol.37 (6), p.1218-1230

2019

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Population pharmacokinetics of exendin‐(9‐39) and clinical dose selection in patients with congenital hyperinsulinism

British journal of clinical pharmacology, 2018-03, Vol.84 (3), p.520-532

2018

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The Pharmacokinetics and Pharmacodynamics of Buprenorphine in Neonatal Abstinence Syndrome

Clinical pharmacology and therapeutics, 2018-06, Vol.103 (6), p.1029-1037

2018

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Mechanism-Based Competitive Binding Model to Investigate the Effect of Neonatal Fc Receptor Binding Affinity on the Pharmacokinetic of Humanized Anti-VEGF Monoclonal IgG1 Antibody in Cynomolgus Monkey

The AAPS journal, 2016-07, Vol.18 (4), p.948-959

2016

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Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients: a population pharmacokinetic analysis

Pharmacogenetics and genomics, 2013-05, Vol.23 (5), p.251-261

2013

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Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome

Pharmacotherapy, 2015-07, Vol.35 (7), p.670-680

2015

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Modeling approach to investigate the effect of neonatal Fc receptor binding affinity and anti-therapeutic antibody on the pharmacokinetic of humanized monoclonal anti-tumor necrosis factor-α IgG antibody in cynomolgus monkey

European journal of pharmaceutical sciences, 2014-01, Vol.51, p.51-58

2014

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Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys

Pharmaceutical research, 2015-06, Vol.32 (6), p.1907-1919

2015

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Effectiveness of a clinical pathway with methadone treatment protocol for treatment of neonatal abstinence syndrome following in utero drug exposure to substances of abuse

Pediatric critical care medicine, 2014-02, Vol.15 (2), p.162-169

2014

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Population pharmacokinetics of phenobarbital in infants with neonatal encephalopathy treated with therapeutic hypothermia

Pediatric critical care medicine, 2013-02, Vol.14 (2), p.194-202

2013

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Using medical claims database to develop a population disease progression model for leuprorelin-treated subjects with hormone-sensitive prostate cancer

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Rational Clinical Dose Selection of Adeno‐Associated Virus‐Mediated Gene Therapy Based on Allometric Principles

Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

Population Pharmacokinetics of Rituximab (Anti-CD20 Monoclonal Antibody) in Rheumatoid Arthritis Patients During a Phase II Clinical Trial

Target-mediated drug disposition model for drugs with N > 2 binding sites that bind to a target with one binding site

GPU-accelerated compartmental modeling analysis of DCE-MRI data from glioblastoma patients treated with bevacizumab

A Modified Hybrid Wald’s Approximation Method for Efficient Covariate Selection in Population Pharmacokinetic Analysis

Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis

General quasi-equilibrium multivalent binding model to study diverse and complex drug-receptor interactions of biologics

Southeast Asian Affairs 1988

Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers

Oxaliplatin Pharmacokinetics and Pharmacodynamics in Adult Cancer Patients with Impaired Renal Function

Incorporation of FcRn-mediated disposition model to describe the population pharmacokinetics of therapeutic monoclonal IgG antibody in clinical patients

Validation of a HPLC/MS method for simultaneous quantification of clonidine, morphine and its metabolites in human plasma

Population pharmacokinetic analysis of AR-67, a lactone stable camptothecin analogue, in cancer patients with solid tumors

Population pharmacokinetics of exendin‐(9‐39) and clinical dose selection in patients with congenital hyperinsulinism

The Pharmacokinetics and Pharmacodynamics of Buprenorphine in Neonatal Abstinence Syndrome

Mechanism-Based Competitive Binding Model to Investigate the Effect of Neonatal Fc Receptor Binding Affinity on the Pharmacokinetic of Humanized Anti-VEGF Monoclonal IgG1 Antibody in Cynomolgus Monkey

Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients: a population pharmacokinetic analysis

Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome

Modeling approach to investigate the effect of neonatal Fc receptor binding affinity and anti-therapeutic antibody on the pharmacokinetic of humanized monoclonal anti-tumor necrosis factor-α IgG antibody in cynomolgus monkey

Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys

Effectiveness of a clinical pathway with methadone treatment protocol for treatment of neonatal abstinence syndrome following in utero drug exposure to substances of abuse

Population pharmacokinetics of phenobarbital in infants with neonatal encephalopathy treated with therapeutic hypothermia

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